(Q36150485)

12 August 2017

1 reference

title

Development of 2A peptide-based strategies in the design of multicistronic vectors (English)

1 reference

12 August 2017

Andrea L Szymczak

1

1 reference

PubMed ID

15934839

12 August 2017

Dario A A Vignali

series ordinal

2

1 reference

PubMed ID

15934839

12 August 2017

language of work or name

English

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publication date

1 May 2005

1 reference

Expert Opinion on Biological Therapy

12 August 2017

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12 August 2017

5

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12 August 2017

627-638

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12 August 2017

5

1 reference

Glioma cells transduced with an Escherichia coli CD/HSV-1 TK fusion gene exhibit enhanced metabolic suicide and radiosensitivity

12 August 2017

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.5.627

Construction and characterization of retroviral vectors expressing biologically active human interleukin-12.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.5.627

Viral vectors for gene transfer: a review of their use in the treatment of human diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.5.627

Viral vectors for gene therapy: the art of turning infectious agents into vehicles of therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.5.627

Development of herpes simplex virus replication-defective multigene vectors for combination gene therapy applications

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.5.627

Polycistronic viral vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.5.627

Transcriptional control: an essential component of cancer gene therapy strategies?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.5.627

Comparison of promoter suppression in avian and murine retrovirus vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.5.627

Expression of Complete Chicken Thymidine Kinase Gene Inserted in a Retrovirus Vector

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.5.627

Efficient retrovirus-mediated transfer and expression of a human adenosine deaminase gene in diploid skin fibroblasts from an adenosine deaminase-deficient human

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.5.627

Transcriptional interference in avian retroviruses—implications for the promoter insertion model of leukaemogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.5.627

Factors affecting long-term stability of Moloney murine leukemia virus-based vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.5.627

Factors affecting retroviral vector function and structural integrity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.5.627

cis-acting regulatory elements within gag genes of avian retroviruses

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.5.627

High mutation rate of a spleen necrosis virus-based retrovirus vector

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.5.627

A new set of positive/negative selectable markers for mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.5.627

Limitations on the use of fused green fluorescent protein to investigate structure-function relationships for the cauliflower mosaic virus movement protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.5.627

Fusagene vectors: a novel strategy for the expression of multiple genes from a single cistron.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.5.627

Internal initiation of translation of eukaryotic mRNA directed by a sequence derived from poliovirus RNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.5.627

Retroviral vectors containing putative internal ribosome entry sites: development of a polycistronic gene transfer system and applications to human gene therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.5.627

Internal ribosome entry sites in eukaryotic mRNA molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.5.627

Characterization of an internal ribosomal entry segment within the 5' leader of avian reticuloendotheliosis virus type A RNA and development of novel MLV-REV-based retroviral vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.5.627

The 5' untranslated region of Rhopalosiphum padi virus contains an internal ribosome entry site which functions efficiently in mammalian, plant, and insect translation systems.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.5.627

Polypurine (A)-rich sequences promote cross-kingdom conservation of internal ribosome entry

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.5.627

The encephalomyocarditis virus internal ribosome entry site allows efficient coexpression of two genes from a recombinant provirus in cultured cells and in embryos

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.5.627

Retroviral coexpression of a multidrug resistance gene (MDR1) and human alpha-galactosidase A for gene therapy of Fabry disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.5.627

The internal ribosomal entry site of the encephalomyocarditis virus enables reliable coexpression of two transgenes in human primary T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.5.627

A retroviral vector that allows efficient co-expression of two genes and the versatility of alternate selection markers

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.5.627

Internal ribosomal entry site-containing retroviral vectors with green fluorescent protein and drug resistance markers

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.5.627

Stably transmitted triple-promoter retroviral vectors and their use in transformation of primary mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.5.627

Generation of mammalian cells stably expressing multiple genes at predetermined levels.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.5.627

Use and comparison of different internal ribosomal entry sites (IRES) in tricistronic retroviral vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.5.627

Alternative ways to think about mRNA sequences and proteins that appear to promote internal initiation of translation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.5.627

Picornavirus internal ribosome entry segments: comparison of translation efficiency and the requirements for optimal internal initiation of translation in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.5.627

Comparison of picornaviral IRES-driven internal initiation of translation in cultured cells of different origins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.5.627

Recognition of picornavirus internal ribosome entry sites within cells; influence of cellular and viral proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.5.627

IRES-dependent second gene expression is significantly lower than cap-dependent first gene expression in a bicistronic vector

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.5.627

Improved vectors for stable expression of foreign genes in mammalian cells by use of the untranslated leader sequence from EMC virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.5.627

Dicistronic transcription units for gene expression in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.5.627

Retrovector encoding a green fluorescent protein-herpes simplex virus thymidine kinase fusion protein serves as a versatile suicide/reporter for cell and gene therapy applications

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.5.627

Composition and arrangement of genes define the strength of IRES-driven translation in bicistronic mRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.5.627

Translation of the human c-myc P0 tricistronic mRNA involves two independent internal ribosome entry sites.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.5.627

A 9-nt segment of a cellular mRNA can function as an internal ribosome entry site (IRES) and when present in linked multiple copies greatly enhances IRES activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.5.627

Development of multigene and regulated lentivirus vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.5.627

Identification of two short internal ribosome entry sites selected from libraries of random oligonucleotides

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.5.627

Reconstitution of a metabolic pathway with triple-cistronic IRES-containing retroviral vectors for correction of tetrahydrobiopterin deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.5.627

Tricistronic viral vectors co-expressing interleukin-12 (1L-12) and CD80 (B7-1) for the immunotherapy of cancer: preclinical studies in myeloma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.5.627

Construction and characterization of polycistronic retrovirus vectors for sustained and high-level co-expression of apolipoprotein A-I and lecithin-cholesterol acyltransferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.5.627

Efficient tumor regression induced by genetically engineered tumor cells secreting interleukin-2 and membrane-expressing allogeneic MHC class I antigen

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.5.627

Skipping the co-expression problem: the new 2A "CHYSEL" technology

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.5.627

Cleavage of foot-and-mouth disease virus polyprotein is mediated by residues located within a 19 amino acid sequence

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.5.627

The 'cleavage' activities of foot-and-mouth disease virus 2A site-directed mutants and naturally occurring '2A-like' sequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.5.627

Retroviral vector-mediated expression of HoxB4 in hematopoietic cells using a novel coexpression strategy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.5.627

Recombinant AAV vectors containing the foot and mouth disease virus 2A sequence confer efficient bicistronic gene expression in cultured cells and rat substantia nigra neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.5.627

Tricistronic and tetracistronic retroviral vectors for gene transfer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.5.627

Co-translational, intraribosomal cleavage of polypeptides by the foot-and-mouth disease virus 2A peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.5.627

Stable, stoichiometric delivery of diverse protein functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.5.627

Use of the 2A sequence from foot-and-mouth disease virus in the generation of retroviral vectors for gene therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.5.627

Construction and characterization of pentacistronic retrovirus vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.5.627

The T cell antigen receptor: insights into organelle biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.5.627

The majority of immunogenic epitopes generate CD4+ T cells that are dependent on MHC class II-bound peptide-flanking residues

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.5.627

21 January 2018

Identifiers

DOI

10.1517/14712598.5.5.627

1 reference

12 August 2017

1 reference

PubMed ID

15934839