(Q36159210)

English

β-Adrenergic receptors stimulate interleukin-6 production through Epac-dependent activation of PKCδ/p38 MAPK signalling in neonatal mouse cardiac fibroblasts

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scholarly article

1 reference

Europe PubMed Central

12 August 2017

β-Adrenergic receptors stimulate interleukin-6 production through Epac-dependent activation of PKCδ/p38 MAPK signalling in neonatal mouse cardiac fibroblasts (English)

1 reference

Europe PubMed Central

12 August 2017

author name string

Chao Chen

1

1 reference

Europe PubMed Central

12 August 2017

Jianhai Du

2

1 reference

Europe PubMed Central

12 August 2017

Wei Feng

3

1 reference

Europe PubMed Central

12 August 2017

Yao Song

4

1 reference

Europe PubMed Central

12 August 2017

Zhizhen Lu

5

1 reference

Europe PubMed Central

12 August 2017

Ming Xu

6

1 reference

Europe PubMed Central

12 August 2017

Zijian Li

7

1 reference

Europe PubMed Central

12 August 2017

Youyi Zhang

8

1 reference

Europe PubMed Central

12 August 2017

language of work or name

0 references

publication date

1 May 2012

1 reference

Europe PubMed Central

12 August 2017

British Journal of Pharmacology

1 reference

Europe PubMed Central

12 August 2017

166

1 reference

Europe PubMed Central

12 August 2017

2

1 reference

Europe PubMed Central

12 August 2017

676-688

1 reference

Europe PubMed Central

12 August 2017

Guide to Receptors and Channels (GRAC), 5th edition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417497

2 October 2017

Interleukin 6 mediates myocardial fibrosis, concentric hypertrophy, and diastolic dysfunction in rats

1 reference

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IGF-1 increases macrophage motility via PKC/p38-dependent alphavbeta3-integrin inside-out signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417497

2 October 2017

Epac: defining a new mechanism for cAMP action

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417497

2 October 2017

Stimulation of adenosine A(2B) receptors induces interleukin-6 secretion in cardiac fibroblasts via the PKC-delta-P38 signalling pathway.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417497

2 October 2017

LPA induces IL-6 secretion from aortic smooth muscle cells via an LPA1-regulated, PKC-dependent, and p38alpha-mediated pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417497

2 October 2017

Role of the cAMP-binding protein Epac in cardiovascular physiology and pathophysiology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417497

2 October 2017

The cAMP binding protein Epac regulates cardiac myofilament function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417497

2 October 2017

Metabolites of an Epac-selective cAMP analog induce cortisol synthesis by adrenocortical cells through a cAMP-independent pathway

1 reference

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Cytokine production through PKC/p38 signaling pathways, not through JAK/STAT1 pathway, in mast cells stimulated with IFNgamma

1 reference

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2 October 2017

Epac mediates PACAP-dependent long-term depression in the hippocampus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417497

2 October 2017

Increased interleukin-6 but not tumour necrosis factor-alpha predicts mortality in the population of elderly heart failure patients

1 reference

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2 October 2017

Epac mediates beta-adrenergic receptor-induced cardiomyocyte hypertrophy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417497

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Novel role of protein kinase C-delta Tyr 311 phosphorylation in vascular smooth muscle cell hypertrophy by angiotensin II.

1 reference

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2 October 2017

Rottlerin: an inappropriate and ineffective inhibitor of PKCdelta

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417497

2 October 2017

Exchange protein activated by cAMP (Epac) mediates cAMP activation of p38 MAPK and modulation of Ca2+-dependent K+ channels in cerebellar neurons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417497

2 October 2017

Serotonin via 5-HT7 receptors activates p38 mitogen-activated protein kinase and protein kinase C epsilon resulting in interleukin-6 synthesis in human U373 MG astrocytoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417497

2 October 2017

Distinctive activation mechanisms and functions for protein kinase Cdelta

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417497

2 October 2017

PKA-dependent activation of PKC, p38 MAPK and IKK in macrophage: implication in the induction of inducible nitric oxide synthase and interleukin-6 by dibutyryl cAMP.

1 reference

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A new phospholipase-C-calcium signalling pathway mediated by cyclic AMP and a Rap GTPase

1 reference

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2 October 2017

Mechanisms underlying extracellular ATP-evoked interleukin-6 release in mouse microglial cell line, MG-5

1 reference

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Phosphorylation sites of protein kinase C delta in H2O2-treated cells and its activation by tyrosine kinase in vitro

1 reference

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2 October 2017

Requirements of protein kinase cdelta for catalytic function. Role of glutamic acid 500 and autophosphorylation on serine 643

1 reference

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A simplified system for generating recombinant adenoviruses

1 reference

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2 October 2017

Interleukin-6 spillover in the peripheral circulation increases with the severity of heart failure, and the high plasma level of interleukin-6 is an important prognostic predictor in patients with congestive heart failure

1 reference

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Novel bradykinin signalling events in PC-12 cells: stimulation of the cAMP pathway leads to cAMP-mediated translocation of protein kinase Cepsilon

1 reference

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2 October 2017

Identification of serine 643 of protein kinase C-delta as an important autophosphorylation site for its enzymatic activity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417497

2 October 2017

cAMP-dependent protein kinase: framework for a diverse family of regulatory enzymes

1 reference

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Cathepsin L is involved in proteolytic processing of the Hendra virus fusion protein

1 reference

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PKCepsilon induces interleukin-6 expression through the MAPK pathway in 3T3-L1 adipocytes

1 reference

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Cholecystokinin-stimulated protein kinase C-delta kinase activation, tyrosine phosphorylation, and translocation are mediated by Src tyrosine kinases in pancreatic acinar cells

1 reference

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Modulation of zeta-protein kinase C by cyclic AMP in PC12 cells occurs through phosphorylation by protein kinase A.

1 reference

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2 July 2018

Epac stimulation induces rapid increases in connexin43 phosphorylation and function without preconditioning effect.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417497

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Steel factor enhances supraoptimal antigen-induced IL-6 production from mast cells via activation of protein kinase C-beta.

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Cyclic nucleotide analogs as probes of signaling pathways.

1 reference

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Angiotensin II-induced extracellular signal-regulated kinase 1/2 activation is mediated by protein kinase Cdelta and intracellular calcium in adult rat cardiac fibroblasts

1 reference

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Epidermal growth factor receptor phosphorylates protein kinase C {delta} at Tyr332 to form a trimeric complex with p66Shc in the H2O2-stimulated cells

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23 September 2018

Noncanonical cAMP pathway and p38 MAPK mediate beta2-adrenergic receptor-induced IL-6 production in neonatal mouse cardiac fibroblasts.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417497

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Regulation of protein kinase C delta by phorbol ester, endothelin-1, and platelet-derived growth factor in cardiac myocytes

1 reference

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23 September 2018

cAMP-binding protein Epac induces cardiomyocyte hypertrophy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417497

23 September 2018

Effect of adenosine triphosphate on phosphate uptake in renal proximal tubule cells: involvement of PKC and p38 MAPK.

1 reference

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Specific gene inhibition by adenovirus-mediated expression of small interfering RNA

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Epac: a new cAMP target and new avenues in cAMP research

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417497

23 September 2018

Translocation of protein kinase C isoforms to subcellular targets in ischemic and anesthetic preconditioning

1 reference

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Regulation of protein kinase C isozyme and calcineurin expression in isoproterenol induced cardiac hypertrophy

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Interleukin-6 family of cytokines mediates isoproterenol-induced delayed STAT3 activation in mouse heart.

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23 September 2018

Cross-regulation of novel protein kinase C (PKC) isoform function in cardiomyocytes. Role of PKC epsilon in activation loop phosphorylations and PKC delta in hydrophobic motif phosphorylations

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Oncostatin M-induced IL-6 expression in murine fibroblasts requires the activation of protein kinase Cdelta

1 reference

https://pubmed.ncbi.nlm.nih.gov/22103274

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Therapeutic use of dopamine and beta-blockers modulates plasma interleukin-6 levels in patients with congestive heart failure

1 reference

https://pubmed.ncbi.nlm.nih.gov/22103274

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacologic preconditioning induced by beta-adrenergic stimulation is mediated by activation of protein kinase C

1 reference

https://pubmed.ncbi.nlm.nih.gov/22103274

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epac1 and cAMP-dependent Protein Kinase Holoenzyme Have Similar cAMP Affinity, but Their cAMP Domains Have Distinct Structural Features and Cyclic Nucleotide Recognition

1 reference

https://pubmed.ncbi.nlm.nih.gov/22103274

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The cAMP binding protein Epac modulates Ca2+ sparks by a Ca2+/calmodulin kinase signalling pathway in rat cardiac myocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/22103274

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antibody against interleukin-6 receptor attenuates left ventricular remodelling after myocardial infarction in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/22103274

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chronic beta-adrenergic stimulation induces myocardial proinflammatory cytokine expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/22103274

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1111/J.1476-5381.2011.01785.X

1 reference

Europe PubMed Central

12 August 2017

1 reference

Europe PubMed Central

12 August 2017

1 reference

Europe PubMed Central

12 August 2017

ResearchGate publication ID

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