(Q36161798)

12 August 2017

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title

Kainic acid-mediated excitotoxicity as a model for neurodegeneration (English)

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12 August 2017

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Qun Wang

1

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12 August 2017

Sue Yu

2

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12 August 2017

Agnes Simonyi

3

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12 August 2017

Grace Y Sun

4

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12 August 2017

Albert Y Sun

5

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12 August 2017

1 January 2005

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12 August 2017

Molecular Neurobiology

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12 August 2017

31

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12 August 2017

3-16

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12 August 2017

1-3

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https://scigraph.springernature.com/pub.10.1385/mn:31:1-3:003

12 August 2017

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cites work

Nitric oxide, mitochondria, and cell death

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12 December 2020

Neuroprotection abilities of cytosolic phospholipase A2 inhibitors in kainic acid-induced neurodegeneration

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12 December 2020

Cytokine induction of iNOS and sPLA2 in immortalized astrocytes (DITNC): response to genistein and pyrrolidine dithiocarbamate

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12 December 2020

Protective effect of resveratrol on oxidative damage in male and female stroke-prone spontaneously hypertensive rats

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12 December 2020

Dendritic localization of Ca(2+)-permeable AMPA/kainate channels in hippocampal pyramidal neurons

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12 December 2020

Protective effects of resveratrol on hydrogen peroxide-induced apoptosis in rat pheochromocytoma (PC12) cells

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12 December 2020

Nuclear factor kappaB activation is mediated by NMDA and non-NMDA receptor and L-type voltage-gated Ca(2+) channel following severe global ischemia in rat hippocampus

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12 December 2020

Nitric oxide synthase induction in astroglial cell cultures: effect on heat shock protein 70 synthesis and oxidant/antioxidant balance

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12 December 2020

Neurochemical consequences of kainate-induced toxicity in brain: involvement of arachidonic acid release and prevention of toxicity by phospholipase A(2) inhibitors

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12 December 2020

Heparan sulfate proteoglycan expression in cerebrovascular amyloid beta deposits in Alzheimer's disease and hereditary cerebral hemorrhage with amyloidosis (Dutch) brains.

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12 December 2020

Role of PKC and MAPK in cytosolic PLA2 phosphorylation and arachadonic acid release in primary murine astrocytes

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12 December 2020

Ethanol and oxidative stress

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12 December 2020

Oxidant-mediated AA release from astrocytes involves cPLA(2) and iPLA(2).

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12 December 2020

Okadaic acid induces hyperphosphorylated forms of tau protein in human brain slices.

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12 December 2020

Dietary vitamin E and physical exercise: II. Antioxidant status and lipofuscin-like substances in aging rat heart

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12 December 2020

Biochemical diagnosis of Alzheimer disease by measuring the cerebrospinal fluid ratio of phosphorylated tau protein to beta-amyloid peptide42.

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12 December 2020

Effects of nimesulide on kainate-induced in vitro oxidative damage in rat brain homogenates

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12 December 2020

Platelet activating factor (PAF) antagonists on cytokine induction of iNOS and sPLA2 in immortalized astrocytes (DITNC).

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12 December 2020

Different effects of genistein and resveratrol on oxidative DNA damage in vitro

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12 December 2020

Down-regulation of GluR2 is associated with Ca2+-dependent protease activities in kainate-induced apoptotic cell death in cultured [correction of culturd] rat hippocampal neurons

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12 December 2020

Expression of C5a receptor in mouse brain: role in signal transduction and neurodegeneration.

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12 December 2020

Secreted phospholipase A2-induced neurotoxicity and epileptic seizures after intracerebral administration: an unexplained heterogeneity as emphasized with paradoxin and crotoxin.

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12 December 2020

Up-regulated production and activation of the complement system in Alzheimer's disease brain

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12 December 2020

Amelioration of oxidative stress by antioxidants and resveratrol in PC12 cells

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12 December 2020

Molecular biology of glutamate receptors in the central nervous system and their role in excitotoxicity, oxidative stress and aging

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12 December 2020

Toxic neuronal apoptosis and modifications of tau and APP gene and protein expressions

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12 December 2020

Mitochondrial dysfunction and reactive oxygen species in excitotoxicity and apoptosis: implications for the pathogenesis of neurodegenerative diseases

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12 December 2020

CNS oxidative stress associated with the kainic acid rodent model of experimental epilepsy

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12 December 2020

Reduced susceptibility to kainic acid-induced excitoxicity in T-cell deficient CD4/CD8(-/-) and middle-aged C57BL/6 mice

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12 December 2020

Microglial activation and increased synthesis of complement component C1q precedes blood-brain barrier dysfunction in rats

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12 December 2020

Distribution of perlecan in mouse hippocampus following intracerebroventricular kainate injections.

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12 December 2020

Ethanol and oxidative mechanisms in the brain

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12 December 2020

Kainate exacerbates beta-amyloid toxicity in rat hippocampus

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12 December 2020

Oxidative damage causes formation of lipofuscin-like substances in the hippocampus of the senescence-accelerated mouse after kainate treatment

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12 December 2020

Neuronal localization of C1q in preclinical Alzheimer's disease

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12 December 2020

Status epilepticus decreases glutamate receptor 2 mRNA and protein expression in hippocampal pyramidal cells before neuronal death

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12 December 2020

Oxidative stress and neurodegenerative disorders

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12 December 2020

Mechanisms of cell death in neurodegenerative disorders.

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12 December 2020

Neuropharmacology of AMPA and kainate receptors

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12 December 2020

Molecular mechanisms of calcium-dependent neurodegeneration in excitotoxicity

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12 December 2020

The biochemical mechanisms of the excitotoxicity of kainic acid. Free radical formation

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12 December 2020

The "French Paradox" and beyond: neuroprotective effects of polyphenols

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12 December 2020

Neuronal apoptosis is associated with a decrease in tau mRNA expression.

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12 December 2020

Inhibition of C1q-beta-amyloid binding protects hippocampal cells against complement mediated toxicity

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12 December 2020

The GluR2 (GluR-B) hypothesis: Ca(2+)-permeable AMPA receptors in neurological disorders

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12 December 2020

Antioxidant activity of resveratrol in red wine

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12 December 2020

Distinct involvement of NF-kappaB and p38 mitogen-activated protein kinase pathways in serum deprivation-mediated stimulation of inducible nitric oxide synthase and its inhibition by 4-hydroxynonenal

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12 December 2020

Cyclooxygenase-2 modulates brain inflammation-related gene expression in central nervous system radiation injury

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12 December 2020

Characterization of neuronal death induced by focally evoked limbic seizures in the C57BL/6 mouse

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12 December 2020

Glutamate as a neurotransmitter in the brain: review of physiology and pathology

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12 December 2020

The role of excitotoxicity in neurodegenerative disease: implications for therapy

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12 December 2020

Phospholipase A2 and its role in brain tissue.

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12 December 2020

Astrocytes as mediators of immune and inflammatory responses in the CNS.

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12 December 2020

Oxidized lipoproteins activate NF-kappaB binding activity and apoptosis in PC12 cells

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12 December 2020

Ethanol-induced cell death by lipid peroxidation in PC12 cells

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12 December 2020

Molecular mechanisms of glutamate-dependent neurodegeneration in ischemia and traumatic brain injury

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12 December 2020

Agrin is a major heparan sulfate proteoglycan accumulating in Alzheimer's disease brain.

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12 December 2020

Complement C1q expression induced by Abeta in rat hippocampal organotypic slice cultures

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12 December 2020

Resveratrol protects against global cerebral ischemic injury in gerbils

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12 December 2020

Effects of resveratrol on the rat brain respiratory chain.

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12 December 2020

Markers of apoptosis and models of programmed cell death in Alzheimer's disease.

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12 December 2020

Distribution of amyloid beta-protein immunoreactivity in the hippocampus of rats injected with kainate

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12 December 2020

Excitotoxins, aging, and environmental neurotoxins: implications for understanding human neurodegenerative diseases

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12 December 2020

Heterogeneity of Ca2+-permeable AMPA/kainate channel expression in hippocampal pyramidal neurons: fluorescence imaging and immunocytochemical assessment.

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12 December 2020

Kainic acid and decorticating lesions stimulate the synthesis of C1q protein in adult rat brain.

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12 December 2020

The effects of excitotoxicity on the expression of the amyloid precursor protein gene in the brain and its modulation by neuroprotective agents

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12 December 2020

Local injection of kainic acid causes widespread degeneration of NADPH-d neurons and induction of NADPH-d in neurons, endothelial cells and reactive astrocytes.

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12 December 2020

Resveratrol protects against neurotoxicity induced by kainic acid

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12 December 2020

Resveratrol inhibition of lipid peroxidation

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12 December 2020

The distribution of beta-amyloid precursor protein in rat cortex after systemic kainate-induced seizures.

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12 December 2020

Kainic acid: insights into excitatory mechanisms causing selective neuronal degeneration

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12 December 2020

Leupeptin causes an accumulation of lipofuscin-like substances and other signs of aging in kidneys of young rats: further evidence for the protease inhibitor model of aging

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12 December 2020

Inflammatory activation of human brain endothelial cells by hypoxic astrocytes in vitro is mediated by IL-1beta

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12 December 2020

Caspase-3-dependent neuronal death in the hippocampus following kainic acid treatment.

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12 December 2020

Glutamate toxicity enhances tau gene expression in neuronal cultures

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12 December 2020

Biological effects of resveratrol

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12 December 2020

Dual role of glutamatergic neurotransmission on amyloid beta(1-42) aggregation and neurotoxicity in embryonic avian retina

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12 December 2020

Mitochondrial dysfunction and oxidative stress in aging and neurodegenerative disease

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12 December 2020

Involvement of nitric oxide in kainic acid-induced excitotoxicity in rat brain

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12 December 2020

Kainate receptors in hippocampal CA3 subregion: evidence for a role in regulating neurotransmitter release

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12 December 2020

Ca2+-Zn2+ permeable AMPA or kainate receptors: possible key factors in selective neurodegeneration

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12 December 2020

Beta-amyloid stimulation of inducible nitric-oxide synthase in astrocytes is interleukin-1beta- and tumor necrosis factor-alpha (TNFalpha)-dependent, and involves a TNFalpha receptor-associated factor- and NFkappaB-inducing kinase-dependent signalin

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12 December 2020

Accumulation of heparan sulfate proteoglycans in cerebellar senile plaques.

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12 December 2020

Modulation of cell death by mouse genotype: differential vulnerability to excitatory amino acid-induced lesions

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12 December 2020

Age dependence of seizure-induced oxidative stress

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12 December 2020

Selective reduction of GluR2 protein in adult hippocampal CA3 neurons following status epilepticus but prior to cell loss.

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12 December 2020

Oxidative mechanisms involved in kainate-induced cytotoxicity in cortical neurons

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12 December 2020

Neuroprotective abilities of resveratrol and other red wine constituents against nitric oxide-related toxicity in cultured hippocampal neurons

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12 December 2020

Pathophysiology of perinatal brain damage

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12 December 2020

In vivo role of caspases in excitotoxic neuronal death: generation and analysis of transgenic mice expressing baculoviral caspase inhibitor, p35, in postnatal neurons

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12 December 2020

Selective vulnerability to kainate-induced oxidative damage in different rat brain regions.

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12 December 2020

Kainic acid-induced excitotoxicity in neurons and glial cells

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12 December 2020

Changes in nitric oxide synthesis and epileptic activity in the contralateral hippocampus of rats following intrahippocampal kainate injection

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12 December 2020

In situ nick end-labeling detects necrosis of hippocampal pyramidal cells induced by kainic acid.

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12 December 2020

Oxidized lipoproteins may play a role in neuronal cell death in Alzheimer disease

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12 December 2020

Identifiers

DOI

10.1385/MN:31:1-3:003

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Dimensions Publication ID

12 August 2017

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