(Q36162950)

12 August 2017

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title

Vascular endothelin in hypertension (English)

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12 August 2017

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Ernesto L Schiffrin

1

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12 August 2017

1 June 2005

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12 August 2017

Vascular Pharmacology

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12 August 2017

43

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12 August 2017

19-29

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12 August 2017

1

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Endothelium-restricted overexpression of human endothelin-1 causes vascular remodeling and endothelial dysfunction

12 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2005.03.004

Myocardial fibrosis in DOCA-salt hypertensive rats: effect of endothelin ET(A) receptor antagonism

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2005.03.004

Fibrosis, matrix metalloproteinases, and inflammation in the heart of DOCA-salt hypertensive rats: role of ET(A) receptors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2005.03.004

Endothelin receptors in human coronary artery and aorta

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VPH.2005.03.004

Activation of resistance arteries with endothelin-1: from vasoconstriction to functional adaptation and remodeling.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2005.03.004

Endothelin ETA receptor-subtype specific antagonism does not mitigate the acute systemic or renal effects of exogenous angiotensin II in humans

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2005.03.004

Release of endothelin from the porcine aorta. Inhibition by endothelium-derived nitric oxide

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2005.03.004

Force-independent expression of c-fos mRNA by endothelin-1 in rat intact small mesenteric arteries

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2005.03.004

ETA receptor blockade decreases vascular superoxide generation in DOCA-salt hypertension

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2005.03.004

Ethnic differences in the vasoconstrictor activity of endogenous endothelin-1 in hypertensive patients

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2005.03.004

Role of endothelin in the increased vascular tone of patients with essential hypertension

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2005.03.004

Improved endothelium-dependent vasodilation after blockade of endothelin receptors in patients with essential hypertension

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2005.03.004

Endothelin and pulmonary hypertension

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2005.03.004

ET(A) and ET(B) receptors modulate the proliferation of human pulmonary artery smooth muscle cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2005.03.004

Endothelin-1 attenuates omega3 fatty acid-induced apoptosis by inhibition of caspase 3.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2005.03.004

PPARalpha activator effects on Ang II-induced vascular oxidative stress and inflammation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2005.03.004

Structure, endothelial function, cell growth, and inflammation in blood vessels of angiotensin II-infused rats: role of peroxisome proliferator-activated receptor-gamma

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2005.03.004

Synthesis and degradation of endothelin-1.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2005.03.004

Endothelin-receptor antagonists in pulmonary hypertension

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2005.03.004

Racial differences in plasma endothelin-1 concentrations in individuals with essential hypertension

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2005.03.004

Distribution of endothelin receptors in saphenous veins of African Americans: implications of racial differences

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2005.03.004

Genes encoding endothelin-converting enzyme-1 and endothelin-1 interact to influence blood pressure in women: the EVA study.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2005.03.004

Differential binding of transcription factor E2F-2 to the endothelin-converting enzyme-1b promoter affects blood pressure regulation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2005.03.004

Endothelin-A receptor antagonism reduces blood pressure and increases renal blood flow in hypertensive patients with chronic renal failure: a comparison of selective and combined endothelin receptor blockade.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2005.03.004

Saphenous vein endothelin system expression and activity in African American patients

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2005.03.004

Direct and sympathetically mediated venoconstriction in essential hypertension. Enhanced responses to endothelin-1.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2005.03.004

Chronic endothelin receptor antagonism prevents coronary vasa vasorum neovascularization in experimental hypercholesterolemia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2005.03.004

Characterization of a coronary vasoconstrictor produced by cultured endothelial cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2005.03.004

Plasma endothelin-1 level is related to renal function and smoking status but not to blood pressure: an epidemiological study

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2005.03.004

Involvement of nuclear factor-kappaB and apoptosis signal-regulating kinase 1 in G-protein-coupled receptor agonist-induced cardiomyocyte hypertrophy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2005.03.004

Angiotensin II induces endothelin-1 gene expression via extracellular signal-regulated kinase pathway in rat aortic smooth muscle cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2005.03.004

Targeted and natural (piebald-lethal) mutations of endothelin-B receptor gene produce megacolon associated with spotted coat color in mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2005.03.004

Treatment of pulmonary arterial hypertension

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2005.03.004

Chronic blockade of endothelin receptors improves ischemia-induced angiogenesis in rat hindlimbs through activation of vascular endothelial growth factor-no pathway

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2005.03.004

Preproendothelin-1 gene polymorphism is related to a change in vascular reactivity in the human mammary artery in vitro

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2005.03.004

Effect of peroxisome proliferator-activated receptor-alpha and -gamma activators on vascular remodeling in endothelin-dependent hypertension

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2005.03.004

Structure and mechanical properties of resistance arteries in hypertension: role of adhesion molecules and extracellular matrix determinants

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2005.03.004

Oxidative stress increases synthesis of big endothelin-1 by activation of the endothelin-1 promoter

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2005.03.004

Oxidative stress increases endothelin-1 synthesis in human coronary artery smooth muscle cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2005.03.004

Endothelin-1 as a target for therapeutic intervention in prostate cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2005.03.004

Myocardial ultrasonic backscatter in hypertension: relation to aldosterone and endothelin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2005.03.004

The effect of an endothelin-receptor antagonist, bosentan, on blood pressure in patients with essential hypertension. Bosentan Hypertension Investigators

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2005.03.004

Elevated blood pressure and craniofacial abnormalities in mice deficient in endothelin-1

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2005.03.004

Increased endothelin-1 content in blood vessels of deoxycorticosterone acetate-salt hypertensive but not in spontaneously hypertensive rats

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2005.03.004

Cardiac microvasculature in DOCA-salt hypertensive rats : effect of endothelin ET(A) receptor antagonism

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2005.03.004

Effect of a nonselective endothelin antagonist on vascular remodeling in deoxycorticosterone acetate-salt hypertensive rats. Evidence for a role of endothelin in vascular hypertrophy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2005.03.004

Effect of endothelin antagonism on blood pressure and vascular structure in renovascular hypertensive rats

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2005.03.004

Endothelin-1 increases vascular superoxide via endothelin(A)-NADPH oxidase pathway in low-renin hypertension

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2005.03.004

Hydrogen peroxide regulation of bovine endothelin-converting enzyme-1.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2005.03.004

Physiological fluid shear stress causes downregulation of endothelin-1 mRNA in bovine aortic endothelium

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2005.03.004

Involvement of nuclear factor-kappaB in endothelin-A-receptor-induced proliferation and inhibition of apoptosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2005.03.004

Stimulatory interaction between vascular endothelial growth factor and endothelin-1 on each gene expression.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2005.03.004

Endothelin-A receptors mediate renal hemodynamic effects of exogenous Angiotensin II in humans

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2005.03.004

Venous smooth muscle contains vasoconstrictor ETB-like receptors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2005.03.004

Role of endogenous endothelin in chronic heart failure: effect of long-term treatment with an endothelin antagonist on survival, hemodynamics, and cardiac remodeling

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2005.03.004

Effect of bosentan on NF-kappaB, inflammation, and tissue factor in angiotensin II-induced end-organ damage

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2005.03.004

Endothelin-converting enzyme inhibition ameliorates angiotensin II-induced cardiac damage

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2005.03.004

Heterodimerization of endothelin-converting enzyme-1 isoforms regulates the subcellular distribution of this metalloprotease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2005.03.004

Darusentan: an effective endothelinA receptor antagonist for treatment of hypertension

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2005.03.004

Permissive role of nitric oxide in endothelin-induced migration of endothelial cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2005.03.004

ET(A) receptor antagonist prevents blood pressure elevation and vascular remodeling in aldosterone-infused rats

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2005.03.004

Cardiac and vascular fibrosis and hypertrophy in aldosterone-infused rats: role of endothelin-1.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2005.03.004

Chronic treatment with a superoxide dismutase mimetic prevents vascular remodeling and progression of hypertension in salt-loaded stroke-prone spontaneously hypertensive rats

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2005.03.004

Endothelin antagonism on aldosterone-induced oxidative stress and vascular remodeling

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2005.03.004

Leptin induces endothelin-1 in endothelial cells in vitro

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2005.03.004

Role for endothelin-1 in angiotensin II-mediated hypertension

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2005.03.004

Blockade of angiotensin II type 1 receptor and not of endothelin receptor prevents hypertension and cardiovascular disease in transgenic (mREN2)27 rats via adrenocortical steroid-independent mechanisms

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2005.03.004

Renal damage is not improved by blockade of endothelin receptors in primary renin-dependent hypertension

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2005.03.004

Endothelin: potential role in hypertension and vascular hypertrophy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2005.03.004

State-of-the-Art lecture. Role of endothelin-1 in hypertension.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2005.03.004

Enhanced expression of endothelin-1 gene in resistance arteries in severe human essential hypertension

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2005.03.004

Peroxisome proliferator-activated receptors: vascular and cardiac effects in hypertension

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2005.03.004

Endothelin-1 as an autocrine/paracrine apoptosis survival factor for endothelial cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2005.03.004

Redox regulation of MAPK pathways and cardiac hypertrophy in adult rat cardiac myocyte

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2005.03.004

The Lys198Asn polymorphism in the endothelin-1 gene is associated with blood pressure in overweight people

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2005.03.004

Endothelin A receptor blockade decreases expression of growth factors and collagen and improves matrix metalloproteinase-2 activity in kidneys from stroke-prone spontaneously hypertensive rats

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2005.03.004

Angiotensin II and endothelin-1 regulate MAP kinases through different redox-dependent mechanisms in human vascular smooth muscle cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2005.03.004

A fourth isoform of endothelin-converting enzyme (ECE-1) is generated from an additional promoter molecular cloning and characterization

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2005.03.004

Endothelin-A receptor antagonist-mediated vasodilatation is attenuated by inhibition of nitric oxide synthesis and by endothelin-B receptor blockade.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2005.03.004

Simulated ischemia in flow-adapted endothelial cells leads to generation of reactive oxygen species and cell signaling

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2005.03.004

A novel potent vasoconstrictor peptide produced by vascular endothelial cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2005.03.004

Threshold concentrations of endothelin-1 potentiate contractions to norepinephrine and serotonin in human arteries. A new mechanism of vasospasm?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2005.03.004

Endothelin-1 production is enhanced by rotenone, a mitochondrial complex I inhibitor, in cultured rat cardiomyocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2005.03.004

10.1016/J.VPH.2005.03.004

7 January 2021

Identifiers

DOI

1 reference

12 August 2017

1 reference

PubMed ID

15955745