(Q36164957)

12 August 2017

ROCK2 primes the endothelium for vascular hyperpermeability responses by raising baseline junctional tension (English)

1 reference

12 August 2017

0 references

Nebojsa Nick Knezevic

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25869521%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Mohammad Tauseef

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25869521%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

author name string

Cora M L Beckers

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25869521%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Erik T Valent

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25869521%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Ramaswamy Krishnan

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25869521%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Kavitha Rajendran

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25869521%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

C Corey Hardin

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25869521%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Jurjan Aman

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25869521%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Jan van Bezu

9

1 reference

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9 June 2020

Paul Sweetnam

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25869521%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Victor W M van Hinsbergh

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25869521%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Dolly Mehta

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25869521%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Geerten P van Nieuw Amerongen

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25869521%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

publication date

11 April 2015

1 reference

12 August 2017

Vascular Pharmacology

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25869521%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

volume

70

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25869521%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

page(s)

45-54

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25869521%20AND%20SRC:MED&resulttype=core&format=json

Rac1 functions as a reversible tension modulator to stabilize VE-cadherin trans-interaction

9 June 2020

cites work

1 reference

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An EMMPRIN-γ-catenin-Nm23 complex drives ATP production and actomyosin contractility at endothelial junctions

2 October 2017

1 reference

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Differential regulation of lung endothelial permeability in vitro and in situ

2 October 2017

1 reference

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Fluid shear stress on endothelial cells modulates mechanical tension across VE-cadherin and PECAM-1.

2 October 2017

1 reference

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Mechanosensitive systems at the cadherin-F-actin interface

2 October 2017

1 reference

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The tension mounts: stress fibers as force-generating mechanotransducers

2 October 2017

1 reference

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ROCK1 & 2 perform overlapping and unique roles in angiogenesis and angiosarcoma tumor progression

2 October 2017

1 reference

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E-cadherin is under constitutive actomyosin-generated tension that is increased at cell-cell contacts upon externally applied stretch

2 October 2017

1 reference

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Vinculin associates with endothelial VE-cadherin junctions to control force-dependent remodeling

2 October 2017

1 reference

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Inhibition of Rho kinases increases directional motility of microvascular endothelial cells

2 October 2017

1 reference

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Collective cell guidance by cooperative intercellular forces

2 October 2017

1 reference

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Cell-ECM traction force modulates endogenous tension at cell-cell contacts.

2 October 2017

1 reference

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The suppression of myosin light chain (MLC) phosphorylation during the response to lipopolysaccharide (LPS): beneficial or detrimental to endothelial barrier?

2 October 2017

1 reference

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Spatially restricted activation of RhoA signalling at epithelial junctions by p114RhoGEF drives junction formation and morphogenesis

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4606924

Shroom2 regulates contractility to control endothelial morphogenesis

2 October 2017

1 reference

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Rho-associated coiled-coil-forming kinases (ROCKs): potential targets for the treatment of atherosclerosis and vascular disease

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4606924

RhoA/ROCK signaling is essential for multiple aspects of VEGF-mediated angiogenesis.

2 October 2017

1 reference

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Role of GTPases in control of microvascular permeability

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4606924

Protein kinase C activation disrupts epithelial apical junctions via ROCK-II dependent stimulation of actomyosin contractility

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4606924

ROCK isoform regulation of myosin phosphatase and contractility in vascular smooth muscle cells

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4606924

Activation of sphingosine kinase-1 reverses the increase in lung vascular permeability through sphingosine-1-phosphate receptor signaling in endothelial cells

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4606924

Comparative gene expression profiling in three primary human cell lines after treatment with a novel inhibitor of Rho kinase or atorvastatin

2 October 2017

1 reference

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Nonmuscle myosin II is responsible for maintaining endothelial cell basal tone and stress fiber integrity

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4606924

ROCK1 mediates leukocyte recruitment and neointima formation following vascular injury

2 October 2017

1 reference

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Thrombin-induced endothelial barrier disruption in intact microvessels: role of RhoA/Rho kinase-myosin phosphatase axis.

2 October 2017

1 reference

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Differential role of Rho GTPases in endothelial barrier regulation dependent on endothelial cell origin.

2 October 2017

1 reference

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Universal physical responses to stretch in the living cell

2 October 2017

1 reference

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Rho kinases in cardiovascular physiology and pathophysiology

2 October 2017

1 reference

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Signaling mechanisms regulating endothelial permeability

2 October 2017

1 reference

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Suppression of RhoA activity by focal adhesion kinase-induced activation of p190RhoGAP: role in regulation of endothelial permeability

2 October 2017

1 reference

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Inhibition of vessel permeability by TNP-470 and its polymer conjugate, caplostatin

2 October 2017

1 reference

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ROCK-I regulates closure of the eyelids and ventral body wall by inducing assembly of actomyosin bundles

2 October 2017

1 reference

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Targeted disruption of the mouse rho-associated kinase 2 gene results in intrauterine growth retardation and fetal death

2 October 2017

1 reference

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Rocks: multifunctional kinases in cell behaviour

2 October 2017

1 reference

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The epidemiology of sepsis in the United States from 1979 through 2000

2 October 2017

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Substrate stiffening promotes endothelial monolayer disruption through enhanced physical forces

2 October 2017

1 reference

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Involvement of Rho kinase in endothelial barrier maintenance

2 July 2018

1 reference

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Sphingosine 1-phosphate rapidly increases endothelial barrier function independently of VE-cadherin but requires cell spreading and Rho kinase

2 July 2018

1 reference

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RhoGDI-1 modulation of the activity of monomeric RhoGTPase RhoA regulates endothelial barrier function in mouse lungs

2 July 2018

1 reference

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Role of RhoA and Rho kinase in lysophosphatidic acid-induced endothelial barrier dysfunction

2 July 2018

1 reference

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F-actin-anchored focal adhesions distinguish endothelial phenotypes of human arteries and veins

2 July 2018

1 reference

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ROCKII Ser1366 phosphorylation reflects the activation status.

23 September 2018

1 reference

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Pretreatment of Rho kinase inhibitor inhibits systemic inflammation and prevents endotoxin-induced acute lung injury in mice.

23 September 2018

1 reference

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Broken barriers: a new take on sepsis pathogenesis.

23 September 2018

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Functional overlap and regulatory links shape genetic interactions between signaling pathways.

23 September 2018

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Activation of Rho kinase isoforms in lung endothelial cells during inflammation

23 September 2018

1 reference

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Functional selectivity of G protein signaling by agonist peptides and thrombin for the protease-activated receptor-1.

23 September 2018

1 reference

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Role of protein kinase Czeta in thrombin-induced endothelial permeability changes: inhibition by angiopoietin-1.

23 September 2018

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Role of Rho GTPases in thrombin-induced lung vascular endothelial cells barrier dysfunction

23 September 2018

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Activation of RhoA by thrombin in endothelial hyperpermeability: role of Rho kinase and protein tyrosine kinases

23 September 2018

1 reference

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STIMulating stress fibers in endothelial cells

7 January 2021

1 reference

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ROCK induced inflammation of the microcirculation during endotoxemia mediated by nitric oxide synthase

7 January 2021

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Exposing Contingency Plans for Kinase Networks

7 January 2021

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10.1016/J.VPH.2015.03.017

7 January 2021

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25869521%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25869521%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

PubMed publication ID

25869521

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25869521%20AND%20SRC:MED&resulttype=core&format=json