(Q36171637)

English

Facultative sterol uptake in an ergosterol-deficient clinical isolate of Candida glabrata harboring a missense mutation in ERG11 and exhibiting cross-resistance to azoles and amphotericin B.

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Europe PubMed Central

PMC publication ID

12 August 2017

Facultative sterol uptake in an ergosterol-deficient clinical isolate of Candida glabrata harboring a missense mutation in ERG11 and exhibiting cross-resistance to azoles and amphotericin B. (English)

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Candida glabrata

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author name string

Claire M Hull

1

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Josie E Parker

2

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Europe PubMed Central

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12 August 2017

Oliver Bader

3

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Europe PubMed Central

PMC publication ID

12 August 2017

Michael Weig

4

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Uwe Gross

5

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Andrew G S Warrilow

6

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Europe PubMed Central

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12 August 2017

Diane E Kelly

7

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Europe PubMed Central

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12 August 2017

Steven L Kelly

8

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12 August 2017

language of work or name

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publication date

21 May 2012

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Europe PubMed Central

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12 August 2017

Antimicrobial Agents and Chemotherapy

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Europe PubMed Central

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12 August 2017

56

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PMC publication ID

12 August 2017

8

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Europe PubMed Central

PMC publication ID

12 August 2017

4223-4232

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Azole drugs are imported by facilitated diffusion in Candida albicans and other pathogenic fungi

1 reference

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1 October 2017

From Saccharomyces cerevisiae to Candida glabratain a few easy steps: important adaptations for an opportunistic pathogen

1 reference

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1 October 2017

Complementation of a Saccharomyces cerevisiae ERG11/CYP51 (Sterol 14α-Demethylase) Doxycycline-Regulated Mutant and Screening of the Azole Sensitivity of Aspergillus fumigatus Isoenzymes CYP51A and CYP51B

1 reference

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1 October 2017

Identification and Characterization of Four Azole-Resistant erg3 Mutants of Candida albicans

1 reference

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1 October 2017

A clinical isolate of Candida albicans with mutations in ERG11 (encoding sterol 14alpha-demethylase) and ERG5 (encoding C22 desaturase) is cross resistant to azoles and amphotericin B.

1 reference

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Sterol biosynthesis and sterol uptake in the fungal pathogen Pneumocystis carinii

1 reference

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1 October 2017

Structural basis of human CYP51 inhibition by antifungal azoles

1 reference

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Acquisition of flucytosine, azole, and caspofungin resistance in Candida glabrata bloodstream isolates serially obtained from a hematopoietic stem cell transplant recipient.

1 reference

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Hypersusceptibility to azole antifungals in a clinical isolate of Candida glabrata with reduced aerobic growth

1 reference

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1 October 2017

Gain of function mutations in CgPDR1 of Candida glabrata not only mediate antifungal resistance but also enhance virulence

1 reference

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Epidemiology of invasive candidiasis: a persistent public health problem

1 reference

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1 October 2017

Isolation of cholesterol-dependent Candida glabrata from clinical specimens

1 reference

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1 October 2017

Mechanisms of azole resistance in clinical isolates of Candida glabrata collected during a hospital survey of antifungal resistance

1 reference

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1 October 2017

Cholesterol import by Aspergillus fumigatus and its influence on antifungal potency of sterol biosynthesis inhibitors

1 reference

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1 October 2017

Rare and emerging opportunistic fungal pathogens: concern for resistance beyond Candida albicans and Aspergillus fumigatus.

1 reference

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1 October 2017

Candida glabrata erg1 mutant with increased sensitivity to azoles and to low oxygen tension

1 reference

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1 October 2017

Mechanisms of azole resistance in petite mutants of Candida glabrata

1 reference

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1 October 2017

Inactivation of transcription factor gene ACE2 in the fungal pathogen Candida glabrata results in hypervirulence

1 reference

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1 October 2017

Phenotypic switching and mating type switching of Candida glabrata at sites of colonization

1 reference

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1 October 2017

Lathosterolosis: an inborn error of human and murine cholesterol synthesis due to lathosterol 5-desaturase deficiency

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3421581

1 October 2017

The enzymes, regulation, and genetics of bile acid synthesis

1 reference

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1 October 2017

Metabolic control analysis and engineering of the yeast sterol biosynthetic pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3421581

1 October 2017

In vitro activities of ravuconazole and voriconazole compared with those of four approved systemic antifungal agents against 6,970 clinical isolates of Candida spp.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3421581

1 October 2017

Amphotericin B: spectrum and resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3421581

1 October 2017

In vitro and in vivo effects of 14alpha-demethylase (ERG11) depletion in Candida glabrata

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3421581

1 October 2017

Role of ATP-binding-cassette transporter genes in high-frequency acquisition of resistance to azole antifungals in Candida glabrata.

1 reference

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Bloodstream infections due to Candida species: SENTRY antimicrobial surveillance program in North America and Latin America, 1997-1998.

1 reference

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1 October 2017

Purification, reconstitution, and inhibition of cytochrome P-450 sterol delta22-desaturase from the pathogenic fungus Candida glabrata.

1 reference

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Candida glabrata: review of epidemiology, pathogenesis, and clinical disease with comparison to C. albicans

1 reference

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1 October 2017

A yeast sterol auxotroph (erg25) is rescued by addition of azole antifungals and reduced levels of heme

1 reference

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Deletion of the Candida glabrata ERG3 and ERG11 genes: effect on cell viability, cell growth, sterol composition, and antifungal susceptibility

1 reference

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A single amino acid substitution converts cytochrome P450(14DM) to an inactive form, cytochrome P450SG1: complete primary structures deduced from cloned DNAS.

1 reference

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2 July 2018

The Candida glabrata putative sterol transporter gene CgAUS1 protects cells against azoles in the presence of serum

1 reference

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23 September 2018

Reduced susceptibility to polyenes associated with a missense mutation in the ERG6 gene in a clinical isolate of Candida glabrata with pseudohyphal growth

1 reference

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Amphotericin B and caspofungin resistance in Candida glabrata isolates recovered from a critically ill patient

1 reference

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Sterol uptake in Candida glabrata: rescue of sterol auxotrophic strains

1 reference

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1 reference

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23 September 2018

Requirement of heme to replace the sparking sterol function in the yeast Saccharomyces cerevisiae

1 reference

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Mode of action and resistance to azole antifungals associated with the formation of 14 alpha-methylergosta-8,24(28)-dien-3 beta,6 alpha-diol.

1 reference

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1 reference

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12 December 2020

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10.1128/AAC.06253-11

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

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