(Q36173568)

12 August 2017

1 reference

title

Nonclinical proarrhythmia models: predicting Torsades de Pointes (English)

1 reference

12 August 2017

1 reference

Chris L Lawrence

1

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12 August 2017

Chris E Pollard

series ordinal

2

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12 August 2017

Tim G Hammond

series ordinal

3

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12 August 2017

Jean-Pierre Valentin

series ordinal

4

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12 August 2017

1 July 2005

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Journal of Pharmacological and Toxicological Methods

12 August 2017

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12 August 2017

52

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12 August 2017

1

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12 August 2017

46-59

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Unique topographical distribution of M cells underlies reentrant mechanism of torsade de pointes in the long-QT syndrome

12 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2005.04.011

Comparative assessment of prurifloxacin, sparfloxacin, gatifloxacin and levofloxacin in the rabbit model of proarrhythmia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2005.04.011

T peak-Tend interval as an index of transmural dispersion of repolarization.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2005.04.011

Arrhythmogenic mechanisms of QT prolonging drugs: is QT prolongation really the problem?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2005.04.011

Cellular mechanisms underlying the long QT syndrome.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2005.04.011

Assessing predictors of drug-induced torsade de pointes.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2005.04.011

Proarrhythmic potential of halofantrine, terfenadine and clofilium in a modified in vivo model of torsade de pointes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2005.04.011

Proarrhythmia of azimilide and other class III antiarrhythmic agents in the adrenergically stimulated rabbit

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2005.04.011

Mortality in patients after a recent myocardial infarction: a randomized, placebo-controlled trial of azimilide using heart rate variability for risk stratification

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2005.04.011

Mexiletine antagonizes effects of sotalol on QT interval duration and its proarrhythmic effects in a canine model of torsade de pointes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2005.04.011

In vivo experimental approach for the risk assessment of fluoroquinolone antibacterial agents-induced long QT syndrome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2005.04.011

Experimental models of torsade de pointes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2005.04.011

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2005.04.011

Proarrhythmic effects of intravenous quinidine, amiodarone, D-sotalol, and almokalant in the anesthetized rabbit model of torsade de pointes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2005.04.011

Differential effect of HERG blocking agents on cardiac electrical alternans in the guinea pig.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2005.04.011

Electrophysiological effects of myocardial stretch and mechanical determinants of stretch-activated arrhythmias

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2005.04.011

Instability and triangulation of the action potential predict serious proarrhythmia, but action potential duration prolongation is antiarrhythmic

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2005.04.011

Phase 2 prolongation, in the absence of instability and triangulation, antagonizes class III proarrhythmia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2005.04.011

Blinded test in isolated female rabbit heart reliably identifies action potential duration prolongation and proarrhythmic drugs: importance of triangulation, reverse use dependence, and instability

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2005.04.011

Female gender does not influence the magnitude of ibutilide-induced repolarization delay and incidence of torsades de pointes in an in vivo rabbit model of the acquired long QT syndrome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2005.04.011

Clofilium in the isolated perfused rabbit heart: a new model to study proarrhythmia induced by class III antiarrhythmic drugs

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2005.04.011

Respective role of sympathetic tone and of cardiac pauses in the genesis of 62 cases of ventricular fibrillation recorded during Holter monitoring.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2005.04.011

Spontaneous sequences of onset of torsade de pointes in patients with acquired prolonged repolarization: quantitative analysis of Holter recordings.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2005.04.011

Ionic bases for electrophysiological distinctions among epicardial, midmyocardial, and endocardial myocytes from the free wall of the canine left ventricle

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2005.04.011

QT and JT dispersion in the drug-induced long QT syndrome in anaesthetized rabbits is accurately detected by a three-lead surface ECG measurement

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2005.04.011

New insight into repolarization abnormalities in patients with congenital long QT syndrome: the increased transmural dispersion of repolarization

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2005.04.011

Divergent proarrhythmic potential of macrolide antibiotics despite similar QT prolongation: fast phase 3 repolarization prevents early afterdepolarizations and torsade de pointes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2005.04.011

Comparison of the in vitro electrophysiologic and proarrhythmic effects of amiodarone and sotalol in a rabbit model of acute atrioventricular block

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2005.04.011

Transmural dispersion of repolarization as a key factor of arrhythmogenicity in a novel intact heart model of LQT3

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2005.04.011

Nature, significance, and mechanisms of electrical heterogeneities in ventricle

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2005.04.011

Relationships between preclinical cardiac electrophysiology, clinical QT interval prolongation and torsade de pointes for a broad range of drugs: evidence for a provisional safety margin in drug development

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2005.04.011

Electrical alternans and vulnerability to ventricular arrhythmias

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2005.04.011

Tridimensional activation patterns of acquired torsade-de-pointes tachycardias in dogs with chronic AV-block

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2005.04.011

Asynchronous development of electrical remodeling and cardiac hypertrophy in the complete AV block dog.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2005.04.011

Regulatory advice on evaluation of the proarrhythmic potential of drugs

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2005.04.011

Increased short-term variability of repolarization predicts d-sotalol-induced torsades de pointes in dogs

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2005.04.011

Electrophysiological safety of sertindole in dogs with normal and remodeled hearts

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2005.04.011

Review of the predictive value of the Langendorff heart model (Screenit system) in assessing the proarrhythmic potential of drugs

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2005.04.011

Azimilide and dofetilide produce similar electrophysiological and proarrhythmic effects in a canine model of Torsade de Pointes arrhythmias

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2005.04.011

Assessment of the pro-arrhythmic potential of anti-arrhythmic drugs: an experimental approach

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2005.04.011

Cellular basis of biventricular hypertrophy and arrhythmogenesis in dogs with chronic complete atrioventricular block and acquired torsade de pointes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2005.04.011

Enhanced susceptibility for acquired torsade de pointes arrhythmias in the dog with chronic, complete AV block is related to cardiac hypertrophy and electrical remodeling

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2005.04.011

Reproducible induction of early afterdepolarizations and torsade de pointes arrhythmias by d-sotalol and pacing in dogs with chronic atrioventricular block.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2005.04.011

Repolarization alternans: implications for the mechanism and prevention of sudden cardiac death

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2005.04.011

Cellular basis for the normal T wave and the electrocardiographic manifestations of the long-QT syndrome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2005.04.011

Phase 2 early afterdepolarization as a trigger of polymorphic ventricular tachycardia in acquired long-QT syndrome : direct evidence from intracellular recordings in the intact left ventricular wall

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2005.04.011

Drug induced QT prolongation and torsades de pointes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2005.04.011

Electrophysiologic features of torsades de pointes: insights from a new isolated rabbit heart model

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2005.04.011

Differential effects of D-sotalol, quinidine, and amiodarone on dispersion of ventricular repolarization in the isolated rabbit heart

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2005.04.011

Torsade de pointes and sudden death induced by thiopental and isoflurane anesthesia in dogs with cardiac electrical remodeling

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2005.04.011

Detection of proarrhythmia in the female rabbit heart: blinded validation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2005.04.011

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/J.VASCN.2005.04.011

1 reference

12 August 2017

1 reference