(Q36187725)

English

Early intervention with gene-modified mesenchymal stem cells overexpressing interleukin-4 enhances anti-inflammatory responses and functional recovery in experimental autoimmune demyelination

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Early intervention with gene-modified mesenchymal stem cells overexpressing interleukin-4 enhances anti-inflammatory responses and functional recovery in experimental autoimmune demyelination (English)

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

1 reference

based on heuristic

inferred from title

mesenchymal stem cell

1 reference

based on heuristic

inferred from title

author name string

Natalie L Payne

1

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Ashanti Dantanarayana

2

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Guizhi Sun

3

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Leon Moussa

4

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Sally Caine

5

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Courtney McDonald

6

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Daniella Herszfeld

7

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Claude C A Bernard

8

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Christopher Siatskas

9

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

language of work or name

1 reference

based on heuristic

inferred from title

publication date

1 May 2012

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Cell Adhesion and Migration

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

6

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

3

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

179-189

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Cytokines and effector T cell subsets causing autoimmune CNS disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3427232

1 October 2017

Vascular inflammation in central nervous system diseases: adhesion receptors controlling leukocyte-endothelial interactions.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3427232

1 October 2017

Mesenchymal stem cells: mechanisms of inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3427232

1 October 2017

Peripheral CD4+ T-cell differentiation regulated by networks of cytokines and transcription factors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3427232

1 October 2017

The prospect of stem cells as multi-faceted purveyors of immune modulation, repair and regeneration in multiple sclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3427232

1 October 2017

Mechanisms of neuronal dysfunction and degeneration in multiple sclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3427232

1 October 2017

How are T(H)2-type immune responses initiated and amplified?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3427232

1 October 2017

Chemokines and chemokine receptors: standing at the crossroads of immunobiology and neurobiology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3427232

1 October 2017

Human mesenchymal stem cells self-renew and differentiate according to a deterministic hierarchy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3427232

1 October 2017

Neuroprotective mesenchymal stem cells are endowed with a potent antioxidant effect in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3427232

1 October 2017

Allogeneic mesenchymal stem cells for treatment of experimental autoimmune encephalomyelitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3427232

1 October 2017

Autoimmune T cell responses in the central nervous system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3427232

1 October 2017

Mesenchymal stromal cells ameliorate experimental autoimmune encephalomyelitis by inhibiting CD4 Th17 T cells in a CC chemokine ligand 2-dependent manner

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3427232

1 October 2017

Human bone marrow-derived mesenchymal stem cells induce Th2-polarized immune response and promote endogenous repair in animal models of multiple sclerosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3427232

1 October 2017

Down-regulation of Gfi-1 expression by TGF-beta is important for differentiation of Th17 and CD103+ inducible regulatory T cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3427232

1 October 2017

The promise of stem cell and regenerative therapies for multiple sclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3427232

1 October 2017

Replicative senescence of mesenchymal stem cells: a continuous and organized process

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3427232

1 October 2017

T cells and NKT cells in the pathogenesis of asthma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3427232

1 October 2017

Multiple sclerosis: a battle between destruction and repair

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3427232

1 October 2017

Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3427232

1 October 2017

Gene therapy strategies towards immune tolerance to treat the autoimmune diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3427232

1 October 2017

A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3427232

1 October 2017

Cytokines in multiple sclerosis: from bench to bedside

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3427232

1 October 2017

The neurite outgrowth inhibitor Nogo A is involved in autoimmune-mediated demyelination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3427232

1 October 2017

The regulation of immunoglobulin E class-switch recombination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3427232

1 October 2017

Myelin oligodendrocyte glycoprotein-specific T cell receptor transgenic mice develop spontaneous autoimmune optic neuritis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3427232

1 October 2017

Alternative activation of macrophages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3427232

1 October 2017

T-cell signalling and autoimmunity: molecular mechanisms of disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3427232

1 October 2017

Delivery to the central nervous system of a nonreplicative herpes simplex type 1 vector engineered with the interleukin 4 gene protects rhesus monkeys from hyperacute autoimmune encephalomyelitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3427232

1 October 2017

Specific Th2 cells accumulate in the central nervous system of mice protected against experimental autoimmune encephalomyelitis by copolymer 1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3427232

1 October 2017

Targeting rare populations of murine antigen-specific T lymphocytes by retroviral transduction for potential application in gene therapy for autoimmune disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3427232

1 October 2017

Multilineage potential of adult human mesenchymal stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3427232

1 October 2017

Local delivery of interleukin 4 by retrovirus-transduced T lymphocytes ameliorates experimental autoimmune encephalomyelitis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3427232

1 October 2017

Cytokine-induced immune deviation as a therapy for inflammatory autoimmune disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3427232

1 October 2017

Adult human mesenchymal cells proliferate and migrate in response to chemokines expressed in demyelination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3427232

2 July 2018

Lentiviral-transduced human mesenchymal stem cells persistently express therapeutic levels of enzyme in a xenotransplantation model of human disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3427232

2 July 2018

In vivo distribution of human adipose-derived mesenchymal stem cells in novel xenotransplantation models

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3427232

2 July 2018

IL-4 directs the development of Th2-like helper effectors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3427232

2 July 2018

Mesenchymal stem cells ameliorate experimental autoimmune encephalomyelitis inducing T-cell anergy.

1 reference

https://api.crossref.org/works/10.4161%2FCAM.20341

21 January 2018

Bone marrow stromal cells reduce axonal loss in experimental autoimmune encephalomyelitis mice.

1 reference

https://api.crossref.org/works/10.4161%2FCAM.20341

21 January 2018

Mesenchymal stem cells effectively modulate pathogenic immune response in experimental autoimmune encephalomyelitis

1 reference

https://api.crossref.org/works/10.4161%2FCAM.20341

21 January 2018

Human mesenchymal stem cells infiltrate the spinal cord, reduce demyelination, and localize to white matter lesions in experimental autoimmune encephalomyelitis.

1 reference

https://api.crossref.org/works/10.4161%2FCAM.20341

21 January 2018

Helper T cell diversity and plasticity

1 reference

https://api.crossref.org/works/10.4161%2FCAM.20341

21 January 2018

IL4 gene delivery to the CNS recruits regulatory T cells and induces clinical recovery in mouse models of multiple sclerosis.

1 reference

https://api.crossref.org/works/10.4161%2FCAM.20341

21 January 2018

Central nervous system gene therapy with interleukin-4 inhibits progression of ongoing relapsing-remitting autoimmune encephalomyelitis in Biozzi AB/H mice.

1 reference

https://api.crossref.org/works/10.4161%2FCAM.20341

21 January 2018

Lentiviral vectors for sustained transgene expression in human bone marrow-derived stromal cells

1 reference

https://api.crossref.org/works/10.4161%2FCAM.20341

21 January 2018

Interleukin-10 delivery via mesenchymal stem cells: a novel gene therapy approach to prevent lung ischemia-reperfusion injury.

1 reference

https://api.crossref.org/works/10.4161%2FCAM.20341

21 January 2018

IL-10-transduced bone marrow mesenchymal stem cells can attenuate the severity of acute graft-versus-host disease after experimental allogeneic stem cell transplantation.

1 reference

https://api.crossref.org/works/10.4161%2FCAM.20341

21 January 2018

Mesenchymal stem cells overexpressing interleukin-10 attenuate collagen-induced arthritis in mice.

1 reference

https://api.crossref.org/works/10.4161%2FCAM.20341

21 January 2018

Molecular trafficking mechanisms of multipotent mesenchymal stem cells derived from human bone marrow and placenta

1 reference

https://api.crossref.org/works/10.4161%2FCAM.20341

21 January 2018

Human mesenchymal stem cells abrogate experimental allergic encephalomyelitis after intraperitoneal injection, and with sparse CNS infiltration

1 reference

https://api.crossref.org/works/10.4161%2FCAM.20341

21 January 2018

Laquinimod (ABR-215062) suppresses the development of experimental autoimmune encephalomyelitis, modulates the Th1/Th2 balance and induces the Th3 cytokine TGF-beta in Lewis rats

1 reference

https://api.crossref.org/works/10.4161%2FCAM.20341

21 January 2018

Human bone marrow stromal cell treatment improves neurological functional recovery in EAE mice

1 reference

https://api.crossref.org/works/10.4161%2FCAM.20341

21 January 2018

Adipose-derived mesenchymal stem cells ameliorate chronic experimental autoimmune encephalomyelitis

1 reference

https://api.crossref.org/works/10.4161%2FCAM.20341

21 January 2018

Human adipose tissue-derived mesenchymal stem cells protect kidneys from cisplatin nephrotoxicity in rats.

1 reference

https://api.crossref.org/works/10.4161%2FCAM.20341

21 January 2018

Systemic transplantation of human adipose stem cells attenuated cerebral inflammation and degeneration in a hemorrhagic stroke model.

1 reference

https://api.crossref.org/works/10.4161%2FCAM.20341

21 January 2018

Induction of a multiple sclerosis-like disease in mice with an immunodominant epitope of myelin oligodendrocyte glycoprotein.

1 reference

https://api.crossref.org/works/10.4161%2FCAM.20341

21 January 2018

A critical role for IL-4 in regulating disease severity in experimental allergic encephalomyelitis as demonstrated in IL-4-deficient C57BL/6 mice and BALB/c mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3427232

23 September 2018

Combination of gene delivery and DNA vaccination to protect from and reverse Th1 autoimmune disease via deviation to the Th2 pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/22568986

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oral tolerance to myelin basic protein and natural recovery from experimental autoimmune encephalomyelitis are associated with downregulation of inflammatory cytokines and differential upregulation of transforming growth factor beta, interleukin 4,

1 reference

https://pubmed.ncbi.nlm.nih.gov/22568986

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-4 (B-cell stimulatory factor-1) augments the in vivo generation of cytotoxic cells in immunosuppressed animals

1 reference

https://pubmed.ncbi.nlm.nih.gov/22568986

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vivo administration of IL-4 induces TGF-beta-producing cells and protects animals from experimental autoimmune encephalomyelitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22568986

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential expression of inflammatory cytokines parallels progression of central nervous system pathology in two clinically distinct models of multiple sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22568986

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Central nervous system delivery of interleukin 4 by a nonreplicative herpes simplex type 1 viral vector ameliorates autoimmune demyelination

1 reference

https://pubmed.ncbi.nlm.nih.gov/22568986

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IL-4 modulation of CD4+CD25+ T regulatory cell-mediated suppression

1 reference

https://pubmed.ncbi.nlm.nih.gov/22568986

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Allogeneic marrow stromal cells are immune rejected by MHC class I- and class II-mismatched recipient mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/22568986

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human bone marrow stromal cells express a distinct set of biologically functional chemokine receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/22568986

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CNS-derived interleukin-4 is essential for the regulation of autoimmune inflammation and induces a state of alternative activation in microglial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/22568986

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MHC expression kinetics and immunogenicity of mesenchymal stromal cells after short-term IFN-γ challenge

1 reference

https://pubmed.ncbi.nlm.nih.gov/22568986

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.4161/CAM.20341

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

ResearchGate publication ID

0 references

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