(Q36196462)

12 August 2017

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title

Nitric oxide donor drugs: an update on pathophysiology and therapeutic potential (English)

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12 August 2017

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Roberto Scatena

1

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12 August 2017

Patrizia Bottoni

series ordinal

2

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12 August 2017

Giuseppe E Martorana

series ordinal

3

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12 August 2017

Bruno Giardina

series ordinal

4

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12 August 2017

language of work or name

English

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publication date

1 July 2005

1 reference

Expert Opinion on Investigational Drugs

12 August 2017

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12 August 2017

14

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12 August 2017

7

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12 August 2017

835-846

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Implications of inducible nitric oxide synthase expression and enzyme activity

12 August 2017

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.7.835

The L-arginine-nitric oxide pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.7.835

Biosynthesis and action of nitric oxide in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.7.835

Nitric oxide donor drugs: current status and future trends

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.7.835

Nitric oxide and cellular respiration

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.7.835

Control of cytochrome c oxidase activity by nitric oxide

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.7.835

Nitric oxide in health and disease of the respiratory system

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.7.835

S-nitrosylation: spectrum and specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.7.835

Free radicals in the physiological control of cell function

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.7.835

Nitric oxide-releasing drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.7.835

Nitric oxide donors and cardiovascular agents modulating the bioactivity of nitric oxide: an overview

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.7.835

Identification of the enzymatic mechanism of nitroglycerin bioactivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.7.835

Nitrates and NO release: contemporary aspects in biological and medicinal chemistry.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.7.835

Role of Mitochondrial Aldehyde Dehydrogenase in Nitrate Tolerance

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.7.835

Nitrate tolerance, oxidative stress, and mitochondrial function: another worrisome chapter on the effects of organic nitrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.7.835

Therapy with NO donors-antiatherogenic and antioxidant actions

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.7.835

NO donors, part 8 [1]: synthesis and vasodilating activities of substituted benzylnitrates compared to cyclohexylmethylnitrate and GTN.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.7.835

The study on organic nitrates, part V. New derivatives of piperazine potential NO donors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.7.835

Therapeutic potential of endothelin receptor antagonists and nitric oxide donors in pulmonary hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.7.835

The biochemistry and physiology of S-nitrosothiols

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.7.835

Chemical synthesis and microvascular effects of new nitric oxide donors in humans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.7.835

Characterisation of GEA 3175 on human platelets; comparison with S-nitroso-N-acetyl-D,L-penicillamine

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.7.835

A novel S-nitrosothiol causes prolonged and selective inhibition of platelet adhesion at sites of vascular injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.7.835

Inhibition of thrombosis by a novel platelet selective S-nitrosothiol compound without hemodynamic side effects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.7.835

Nitrosoglutathione modulation of platelet activation and nitric oxide synthase expression in promotion of flap survival after ischemia/reperfusion injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.7.835

The nitric oxide donor S-nitroso-N-acetylpenicillamine (SNAP) increases free radical generation and degrades left ventricular function after myocardial ischemia-reperfusion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.7.835

S-nitrosothiol-induced rapid cytochrome c release, caspase activation and mitochondrial permeability transition in perfused heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.7.835

S-nitrosoalbumin-mediated relaxation is enhanced by ascorbate and copper: effects in pregnancy and preeclampsia plasma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.7.835

Inhibition of SARS-coronavirus infection in vitro by S-nitroso-N-acetylpenicillamine, a nitric oxide donor compound

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.7.835

Essential roles of S-nitrosothiols in vascular homeostasis and endotoxic shock

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.7.835

Nitric oxide and BCNU chemoresistance in C6 glioma cells: role of S-nitrosoglutathione

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.7.835

Topically applied S-nitrosothiol-containing hydrogels as experimental and pharmacological nitric oxide donors in human skin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.7.835

Progress toward clinical application of the nitric oxide-releasing diazeniumdiolates

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.7.835

Inhibition of rat platelet aggregation by the diazeniumdiolate nitric oxide donor MAHMA NONOate

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.7.835

Inhaled diazeniumdiolates (NONOates) as selective pulmonary vasodilators

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.7.835

Polymers incorporating nitric oxide releasing/generating substances for improved biocompatibility of blood-contacting medical devices

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.7.835

Nitric oxide-releasing biopolymers inhibit thrombus formation in a sheep model of arteriovenous bridge grafts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.7.835

Nitric oxide-releasing hydrophobic polymers: preparation, characterization, and potential biomedical applications

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.7.835

Augmentation of intrapericardial nitric oxide level by a prolonged-release nitric oxide donor reduces luminal narrowing after porcine coronary angioplasty

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.7.835

Effects of diazeniumdiolates (NONOates) and methylene blue on the reduction of postoperative adhesion in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.7.835

Nitric oxide and chemically induced hepatotoxicity: beneficial effects of the liver-selective nitric oxide donor, V-PYRRO/NO.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.7.835

JS-K, a novel non-ionic diazeniumdiolate derivative, inhibits Hep 3B hepatoma cell growth and induces c-Jun phosphorylation via multiple MAP kinase pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.7.835

Nitric-oxide-donating NSAIDs as agents for cancer prevention

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.7.835

In vitro and in vivo evaluation of NCX 4040 cytotoxic activity in human colon cancer cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.7.835

Evaluation of the antitumoral potential of different nitric oxide-donating non-steroidal anti-inflammatory drugs (NO-NSAIDs) on human urological tumor cell lines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.7.835

Nitric oxide donating nonsteroidal anti-inflammatory drugs induce apoptosis in human prostate cancer cell systems and human prostatic stroma via caspase-3

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.7.835

Nitric oxide-releasing non steroidal anti-inflammatory drugs: a new generation of anti-tumoral molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.7.835

Gastrointestinal safety of NO-aspirin (NCX-4016) in healthy human volunteers: a proof of concept endoscopic study

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.7.835

Co-administration of nitric oxide-aspirin (NCX-4016) and aspirin prevents platelet and monocyte activation and protects against gastric damage induced by aspirin in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.7.835

Nitric oxide-releasing aspirin derivative, NCX 4016, promotes reparative angiogenesis and prevents apoptosis and oxidative stress in a mouse model of peripheral ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.7.835

Potential cardioprotective actions of no-releasing aspirin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.7.835

Efficacy and age-related effects of nitric oxide-releasing aspirin on experimental restenosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.7.835

Nitric oxide-releasing aspirin inhibits vasoconstriction in perfused tail artery of normotensive and spontaneously hypertensive rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.7.835

Antiinflammatory, gastrosparing, and antiplatelet properties of new NO-donor esters of aspirin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.7.835

The effects and metabolic fate of nitroflurbiprofen in healthy volunteers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.7.835

A nitric oxide releasing derivative of flurbiprofen inhibits experimental autoimmune encephalomyelitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.7.835

A nitric oxide-donating flurbiprofen derivative reduces neuroinflammation without interacting with galantamine in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.7.835

The effects of sham and full spinalization on the antinociceptive effects of NCX-701 (nitroparacetamol) in monoarthritic rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.7.835

Gastrointestinal safety of AZD3582, a cyclooxygenase inhibiting nitric oxide donator: proof of concept study in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.7.835

The CINOD, AZD3582, exhibits an improved gastrointestinal safety profile compared with naproxen in healthy volunteers

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.7.835

A common pathway of nitric oxide release from AZD3582 and glyceryl trinitrate

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.7.835

Comparative effects of inhaled budesonide and the NO-donating budesonide derivative, NCX 1020, against leukocyte influx and airway hyperreactivity following lipopolysaccharide challenge

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.7.835

Synthesis of nitro esters of prednisolone, new compounds combining pharmacological properties of both glucocorticoids and nitric oxide

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.7.835

21-NO-prednisolone is a novel nitric oxide-releasing derivative of prednisolone with enhanced anti-inflammatory properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.7.835

Enhanced anti-inflammatory potency of a nitric oxide-releasing derivative of flunisolide: role of nuclear factor-kappaB

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.7.835

Potent antiarthritic properties of a glucocorticoid derivative, NCX-1015, in an experimental model of arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.7.835

A nitric oxide-releasing salbutamol elicits potent relaxant and anti-inflammatory activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.7.835

In vitro effects of a novel class of nitric oxide (NO) donating compounds on isolated human erectile tissue

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.7.835

Development of a new class of potential antiatherosclerosis agents: NO-donor antioxidants.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.7.835

Liver delivery of NO by NCX-1000 protects against acute liver failure and mitochondrial dysfunction induced by APAP in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.7.835

NCX-1000, a nitric oxide-releasing derivative of ursodeoxycholic acid, ameliorates portal hypertension and lowers norepinephrine-induced intrahepatic resistance in the isolated and perfused rat liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.7.835

NCX-1000, a NO-releasing derivative of ursodeoxycholic acid, selectively delivers NO to the liver and protects against development of portal hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.7.835

A new furoxan NO-donor rabeprazole derivative and related compounds

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.7.835

10.1517/13543784.14.7.835

21 January 2018

Identifiers

DOI

1 reference

12 August 2017

1 reference