(Q36202218)

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Induction of rapid and highly efficient expression of the human ND4 complex I subunit in the mouse visual system by self-complementary adeno-associated virus.

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scholarly article

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20625049%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

Induction of rapid and highly efficient expression of the human ND4 complex I subunit in the mouse visual system by self-complementary adeno-associated virus (English)

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20625049%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

William W Hauswirth

4

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20625049%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

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Rajeshwari D Koilkonda

1

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7 February 2020

Tsung-Han Chou

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20625049%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

Vittorio Porciatti

3

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7 February 2020

John Guy

5

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7 February 2020

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1 July 2010

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7 February 2020

JAMA Ophthalmology

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20625049%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

128

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7 February 2020

7

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7 February 2020

876-883

1 reference

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PMC publication ID

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7 February 2020

Mitochondrial gene replacement in primate offspring and embryonic stem cells

1 reference

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1 October 2017

Efficiency and safety of AAV-mediated gene delivery of the human ND4 complex I subunit in the mouse visual system

1 reference

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1 October 2017

Mitochondrial gene therapy augments mitochondrial physiology in a Parkinson's disease cell model

1 reference

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1 October 2017

High-efficiency transduction of the mouse retina by tyrosine-mutant AAV serotype vectors

1 reference

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1 October 2017

Intraocular route of AAV2 vector administration defines humoral immune response and therapeutic potential

1 reference

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1 October 2017

Treatment of leber congenital amaurosis due to RPE65 mutations by ocular subretinal injection of adeno-associated virus gene vector: short-term results of a phase I trial

1 reference

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1 October 2017

Optimized allotopic expression of the human mitochondrial ND4 prevents blindness in a rat model of mitochondrial dysfunction

1 reference

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1 October 2017

Next generation of adeno-associated virus 2 vectors: point mutations in tyrosines lead to high-efficiency transduction at lower doses

1 reference

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1 October 2017

Safety and efficacy of gene transfer for Leber's congenital amaurosis

1 reference

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1 October 2017

Immunity to adeno-associated virus vectors in animals and humans: a continued challenge

1 reference

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1 October 2017

Modulating mtDNA heteroplasmy by mitochondria-targeted restriction endonucleases in a 'differential multiple cleavage-site' model

1 reference

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Approaches to the treatment of mitochondrial diseases

1 reference

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1 October 2017

Parkinson's disease brain mitochondrial complex I has oxidatively damaged subunits and is functionally impaired and misassembled.

1 reference

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1 October 2017

Mechanisms of AAV transduction in glaucoma-associated human trabecular meshwork cells

1 reference

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1 October 2017

Self-complementary adeno-associated virus vectors containing a novel liver-specific human factor IX expression cassette enable highly efficient transduction of murine and nonhuman primate liver

1 reference

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1 October 2017

Rapid directional shift of mitochondrial DNA heteroplasmy in animal tissues by a mitochondrially targeted restriction endonuclease

1 reference

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1 October 2017

Prophylaxis for second eye involvement in leber hereditary optic neuropathy: an open-labeled, nonrandomized multicenter trial of topical brimonidine purite

1 reference

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1 October 2017

Adeno-associated virus: from defective virus to effective vector

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431796

1 October 2017

Custom adeno-associated virus capsids: the next generation of recombinant vectors with novel tropism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431796

1 October 2017

Circulating anti-wild-type adeno-associated virus type 2 (AAV2) antibodies inhibit recombinant AAV2 (rAAV2)-mediated, but not rAAV5-mediated, gene transfer in the brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431796

1 October 2017

Limitations of Allotopic Expression of Mitochondrial Genes in Mammalian Cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431796

1 October 2017

The atomic structure of adeno-associated virus (AAV-2), a vector for human gene therapy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431796

1 October 2017

Rescue of a deficiency in ATP synthesis by transfer of MTATP6, a mitochondrial DNA-encoded gene, to the nucleus

1 reference

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1 October 2017

Cross-packaging of a single adeno-associated virus (AAV) type 2 vector genome into multiple AAV serotypes enables transduction with broad specificity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431796

1 October 2017

Self-complementary recombinant adeno-associated virus (scAAV) vectors promote efficient transduction independently of DNA synthesis

1 reference

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1 October 2017

Protein import into mitochondria

1 reference

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1 October 2017

Pedigree analysis in Leber hereditary optic neuropathy families with a pathogenic mtDNA mutation

1 reference

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Rapid, widespread transduction of the murine myocardium using self-complementary Adeno-associated virus

1 reference

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IOP-dependent retinal ganglion cell dysfunction in glaucomatous DBA/2J mice

1 reference

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High-level transgene expression in nonhuman primate liver with novel adeno-associated virus serotypes containing self-complementary genomes

1 reference

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Ocular gene transfer with self-complementary AAV vectors

1 reference

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22 September 2018

The mutant human ND4 subunit of complex I induces optic neuropathy in the mouse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431796

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1 reference

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Self-complementary adeno-associated virus serotype 2 vector: global distribution and broad dispersion of AAV-mediated transgene expression in mouse brain

1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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Import of proteins into mitochondria

1 reference

https://pubmed.ncbi.nlm.nih.gov/20625049

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The clinical features of Leber's hereditary optic neuropathy defined by the presence of a pathogenic mitochondrial DNA mutation

1 reference

https://pubmed.ncbi.nlm.nih.gov/20625049

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1001/ARCHOPHTHALMOL.2010.135

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20625049%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20625049%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20625049%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

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