(Q36217387)

12 August 2017

Amino-terminal cysteine residues differentially influence RGS4 protein plasma membrane targeting, intracellular trafficking, and function (English)

1 reference

12 August 2017

Guillaume Bastin

1

1 reference

12 August 2017

Kevin Singh

2

1 reference

12 August 2017

Kaveesh Dissanayake

3

1 reference

12 August 2017

Alexandra S Mighiu

4

1 reference

12 August 2017

Aliya Nurmohamed

5

1 reference

12 August 2017

Scott P Heximer

6

1 reference

12 August 2017

language of work or name

English

0 references

publication date

29 June 2012

1 reference

Journal of Biological Chemistry

12 August 2017

1 reference

12 August 2017

287

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12 August 2017

34

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12 August 2017

28966-28974

1 reference

describes a project that uses

12 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3436580/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Palmitoylation and trafficking of GAD65 are impaired in a cellular model of Huntington's disease

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Posttranslational regulation of AMPA receptor trafficking and function

1 October 2017

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Protein palmitoylation and subcellular trafficking

1 October 2017

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Gi/o signaling and the palmitoyltransferase DHHC2 regulate palmitate cycling and shuttling of RGS7 family-binding protein

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436580

DHHC protein-dependent palmitoylation protects regulator of G-protein signaling 4 from proteasome degradation.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436580

Palmitoylated Ras proteins traffic through recycling endosomes to the plasma membrane during exocytosis.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436580

RGS4 is a negative regulator of insulin release from pancreatic beta-cells in vitro and in vivo

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436580

Direct observation and quantitative analysis of Lck exchange between plasma membrane and cytosol in living T cells

1 October 2017

1 reference

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Breast cancer migration and invasion depend on proteasome degradation of regulator of G-protein signaling 4.

1 October 2017

1 reference

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Identification of G protein alpha subunit-palmitoylating enzyme

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436580

RGS4 regulates parasympathetic signaling and heart rate control in the sinoatrial node

1 October 2017

1 reference

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Unique hydrophobic extension of the RGS2 amphipathic helix domain imparts increased plasma membrane binding and function relative to other RGS R4/B subfamily members.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436580

N-terminal residues control proteasomal degradation of RGS2, RGS4, and RGS5 in human embryonic kidney 293 cells

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436580

Adrenergic modulation of NMDA receptors in prefrontal cortex is differentially regulated by RGS proteins and spinophilin

1 October 2017

1 reference

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Homer 2 tunes G protein-coupled receptors stimulus intensity by regulating RGS proteins and PLCbeta GAP activities

1 October 2017

1 reference

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Palmitoylation regulates regulator of G-protein signaling (RGS) 16 function. II. Palmitoylation of a cysteine residue in the RGS box is critical for RGS16 GTPase accelerating activity and regulation of Gi-coupled signalling

1 October 2017

1 reference

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RGS7 is palmitoylated and exists as biochemically distinct forms

1 October 2017

1 reference

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RGS4 and RGS2 bind coatomer and inhibit COPI association with Golgi membranes and intracellular transport

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436580

GTPase-activating proteins for heterotrimeric G proteins: regulators of G protein signaling (RGS) and RGS-like proteins

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436580

Ca2+/Calmodulin reverses phosphatidylinositol 3,4, 5-trisphosphate-dependent inhibition of regulators of G protein-signaling GTPase-activating protein activity

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436580

H-ras but not K-ras traffics to the plasma membrane through the exocytic pathway

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436580

Palmitoylation of a conserved cysteine in the regulator of G protein signaling (RGS) domain modulates the GTPase-activating activity of RGS4 and RGS10

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436580

Plasma membrane localization is required for RGS4 function in Saccharomyces cerevisiae

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436580

RGS family members: GTPase-activating proteins for heterotrimeric G-protein alpha-subunits

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436580

GAIP and RGS4 are GTPase-activating proteins for the Gi subfamily of G protein alpha subunits

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436580

TGN38/41 recycles between the cell surface and the TGN: brefeldin A affects its rate of return to the TGN.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436580

Palmitoylation of multiple Src-family kinases at a homologous N-terminal motif

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436580

RGS4 is arginylated and degraded by the N-end rule pathway in vitro

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436580

Increased GABA(B) receptor-mediated signaling reduces the susceptibility of fragile X knockout mice to audiogenic seizures

29 June 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.345629

RGS4 binds to membranes through an amphipathic alpha -helix.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.345629

RGS2-mediated regulation of Gqalpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.345629

Differential trafficking of Src, Lyn, Yes and Fyn is specified by the state of palmitoylation in the SH4 domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.345629

Inhibition of Galphaq-dependent PLC-beta1 activity by PKG and PKA is mediated by phosphorylation of RGS4 and GRK2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.345629

21 January 2018

Identifiers

DOI

10.1074/JBC.M112.345629

1 reference

12 August 2017

1 reference

12 August 2017

1 reference