(Q36222559)

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Isolation and characterization of Chinese hamster ovary cell mutants defective in intracellular low density lipoprotein-cholesterol trafficking

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:2404988%20AND%20SRC:MED&resulttype=core&format=json

28 September 2019

Isolation and characterization of Chinese hamster ovary cell mutants defective in intracellular low density lipoprotein-cholesterol trafficking (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:2404988%20AND%20SRC:MED&resulttype=core&format=json

28 September 2019

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28 September 2019

author name string

D M Spillane

2

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28 September 2019

T Y Chang

3

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28 September 2019

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1 February 1990

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28 September 2019

number of pages

14

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Journal of Cell Biology

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28 September 2019

110

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28 September 2019

2

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Europe PubMed Central

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28 September 2019

295-308

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Europe PubMed Central

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28 September 2019

describes a project that uses

0 references

0 references

0 references

Protein measurement with the Folin phenol reagent

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2116012

1 October 2017

Isolation of Chinese hamster cell mutants deficient in dihydrofolate reductase activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2116012

1 October 2017

Mevinolin: a highly potent competitive inhibitor of hydroxymethylglutaryl-coenzyme A reductase and a cholesterol-lowering agent

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2116012

1 October 2017

Lysosome lipid storage disorder in NCTR-BALB/c mice. II. Morphologic and cytochemical studies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2116012

1 October 2017

Lysosome lipid storage disorder in NCTR-BALB/c mice. I. Description of the disease and genetics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2116012

1 October 2017

Progress in understanding the LDL receptor and HMG-CoA reductase, two membrane proteins that regulate the plasma cholesterol.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2116012

1 October 2017

Lysosome lipid storage disorder in NCTR-BALB/c mice. III. Isolation and analysis of storage inclusions from liver

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2116012

1 October 2017

Receptor-mediated endocytosis of low density lipoprotein: somatic cell mutants define multiple genes required for expression of surface-receptor activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2116012

1 October 2017

An alternative procedure for incorporating radiolabelled cholesteryl ester into human plasma lipoproteins in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2116012

1 October 2017

A defect in cholesterol esterification in Niemann-Pick disease (type C) patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2116012

1 October 2017

Niemann-pick variant disorders: comparison of errors of cellular cholesterol homeostasis in group D and group C fibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2116012

1 October 2017

Type-C Niemann-Pick disease: low density lipoprotein uptake is associated with premature cholesterol accumulation in the Golgi complex and excessive cholesterol storage in lysosomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2116012

1 October 2017

Subcellular localization of sterol carrier protein-2 in rat hepatocytes: its primary localization to peroxisomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2116012

1 October 2017

Isolation of Chinese hamster ovary cell lines expressing human acyl-coenzyme A/cholesterol acyltransferase activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2116012

1 October 2017

The intracellular transport of low density lipoprotein-derived cholesterol is defective in Niemann-Pick type C fibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2116012

1 October 2017

A simplification of the protein assay method of Lowry et al. which is more generally applicable

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2116012

1 October 2017

The Low-Density Lipoprotein Pathway and its Relation to Atherosclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2116012

1 October 2017

Role of lysosomal acid lipase in the metabolism of plasma low density lipoprotein. Observations in cultured fibroblasts from a patient with cholesteryl ester storage disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2116012

1 October 2017

The picomole determination of free and total cholesterol in cells in culture

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2116012

1 October 2017

Revertants of a Chinese hamster ovary cell mutant resistant to suppression by an analogue of cholesterol: isolation and partial biochemical characterization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2116012

29 June 2018

The participation of sterol carrier protein2 in the conversion of cholesterol to cholesterol ester by rat liver microsomes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2116012

29 June 2018

Smooth microsomes. a trap for cholesteryl ester formed in hepatic microsomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2116012

29 June 2018

Regulation of cytosolic acetoacetyl coenzyme A thiolase, 3-hydroxy-3-methylglutaryl coenzyme A synthase, 3-hydroxy-3-methylglutaryl coenzyme A reductase, and mevalonate kinase by low density lipoprotein and by 25-hydroxycholesterol in Chinese hamste

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2116012

29 June 2018

Mutations affecting adenine phosphoribosyl transferase activity in Chinese hamster cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2116012

29 June 2018

Cycloheximide sensitivity in regulation of acyl coenzyme A:cholesterol acyltransferase activity in Chinese hamster ovary cells. 2. Effect of sterol endogenously synthesized

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2116012

29 June 2018

Isolation and characterization of Chinese hamster ovary cell mutants deficient in acyl-coenzyme A:cholesterol acyltransferase activity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2116012

29 June 2018

Type C Niemann-Pick disease. Lysosomal accumulation and defective intracellular mobilization of low density lipoprotein cholesterol.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2116012

29 June 2018

Expression of transformation in cell hybrids. I. Isolation and application of density-inhibited Balb/3T3 cells deficient in hypoxanthine phosphoribosyltransferase and resistant to ouabain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2116012

29 June 2018

A solvent system for delipidation of plasma or serum without protein precipitation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2116012

29 June 2018

The submicrosomal localization of acyl-coenzyme A-cholesterol acyltransferase and its substrate, and of cholesteryl esters in rat liver

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2116012

29 June 2018

Evidence obtained by induced mutation frequency analysis for functional hemizygosity at theemt locus in CHO cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2116012

29 June 2018

Cycloheximide sensitivity in regulation of acyl coenzyme A:cholesterol acyltransferase activity in Chinese hamster ovary cells. 1. Effect of exogenous sterols

1 reference

https://pubmed.ncbi.nlm.nih.gov/2404988

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of cholesterol esterification and biosynthesis in monolayer cultures of normal adult rat hepatocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/2404988

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A method for the chemical synthesis of 14C-labeled fatty acyl coenzyme A's of high specific activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/2404988

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A lysosomal storage disorder in mice characterized by a dual deficiency of sphingomyelinase and glucocerebrosidase

1 reference

https://pubmed.ncbi.nlm.nih.gov/2404988

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for coordinate expression of 3-hydroxy-3-methylglutaryl coenzyme A reductase ad low density lipoprotein binding activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/2404988

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A simple and efficient procedure for the rapid homogenization of cultured animal cells grown in monolayer

1 reference

https://pubmed.ncbi.nlm.nih.gov/2404988

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isolation of Chinese hamster cell mutants defective in the receptor-mediated endocytosis of low density lipoprotein

1 reference

https://pubmed.ncbi.nlm.nih.gov/2404988

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased cholesterol esterification in rat liver microsomes in purified non-specific phospholipid transfer protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/2404988

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acyl-CoA:cholesterol acyltransferase in Chinese hamster ovary cells. Enzyme activity determined after reconstitution in phospholipid/cholesterol liposomes

1 reference

https://pubmed.ncbi.nlm.nih.gov/2404988

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure of mutant alleles at the aprt locus of Chinese hamster ovary cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/2404988

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective inhibition of acyl coenzyme A:cholesterol acyltransferase by compound 58-035

1 reference

https://pubmed.ncbi.nlm.nih.gov/2404988

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

19 Receptor-mediated endocytosis of low-density lipoprotein in cultured cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/2404988

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Type C Niemann-Pick disease. Abnormal metabolism of low density lipoprotein in homozygous and heterozygous fibroblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/2404988

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Group C Niemann-Pick disease: faulty regulation of low-density lipoprotein uptake and cholesterol storage in cultured fibroblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/2404988

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Low density lipoprotein (LDL)-mediated suppression of cholesterol synthesis and LDL uptake is defective in Niemann-Pick type C fibroblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/2404988

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A simple method for reconstitution of CHO cell and human fibroblast acyl coenzyme A: cholesterol acyltransferase activity into liposomes

1 reference

https://pubmed.ncbi.nlm.nih.gov/2404988

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Staining of cholesterol with the fluorescent antibiotic "filipin"

1 reference

https://pubmed.ncbi.nlm.nih.gov/2404988

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ultrastructural localization of a peroxisomal protein in rat liver using the specific antibody against the non-specific lipid transfer protein (sterol carrier protein 2)

1 reference

https://pubmed.ncbi.nlm.nih.gov/2404988

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression and regulation of human low-density lipoprotein receptors in Chinese hamster ovary cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/2404988

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A genetic storage disorder in BALB/C mice with a metabolic block in esterification of exogenous cholesterol

1 reference

https://pubmed.ncbi.nlm.nih.gov/2404988

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1083/JCB.110.2.295

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:2404988%20AND%20SRC:MED&resulttype=core&format=json

28 September 2019

release_efzqvqslt5dqbankbdekkbqqpy

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24 November 2022

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PMC publication ID

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:2404988%20AND%20SRC:MED&resulttype=core&format=json

28 September 2019

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:2404988%20AND%20SRC:MED&resulttype=core&format=json

28 September 2019

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