(Q36225177)

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Cardiac systems biology

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scholarly article

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Europe PubMed Central

12 August 2017

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Europe PubMed Central

Cardiac systems biology (English)

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Europe PubMed Central

12 August 2017

author name string

Andrew D McCulloch

1

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Europe PubMed Central

12 August 2017

Giovanni Paternostro

2

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Europe PubMed Central

12 August 2017

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publication date

1 June 2005

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Europe PubMed Central

12 August 2017

Annals of the New York Academy of Sciences

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Europe PubMed Central

12 August 2017

1047

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Europe PubMed Central

12 August 2017

283-295

1 reference

Europe PubMed Central

12 August 2017

Genetic dissection of complex traits with chromosome substitution strains of mice.

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The genome sequence of Drosophila melanogaster

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A Drosophila model of Parkinson's disease

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Genetic suppression of polyglutamine toxicity in Drosophila

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Preventing neurodegeneration in the Drosophila mutant bubblegum

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Extended life-span and stress resistance in the Drosophila mutant methuselah

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Extended life-span conferred by cotransporter gene mutations in Drosophila.

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Age-associated cardiac dysfunction in Drosophila melanogaster

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Effects of deuterium oxide and temperature on heart rate in Drosophila melanogaster

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Effects of temperature on the life span, vitality and fine structure of Drosophila melanogaster

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Mutations affecting segment number and polarity in Drosophila

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Genetic control of programmed cell death in Drosophila

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Molecular cloning of Notch, a locus affecting neurogenesis in Drosophila melanogaster

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A survey of human disease gene counterparts in the Drosophila genome

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A systematic analysis of human disease-associated gene sequences in Drosophila melanogaster

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Introduction: chronic heart failure in older persons

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Protein networks, pleiotropy and the evolution of senescence.

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Cardiac Action and Pacemaker Potentials based on the Hodgkin-Huxley Equations

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A quantitative description of membrane current and its application to conduction and excitation in nerve

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Approaches to modeling crossbridges and calcium-dependent activation in cardiac muscle.

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An integrated model of cardiac mitochondrial energy metabolism and calcium dynamics

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Model study of ATP and ADP buffering, transport of Ca(2+) and Mg(2+), and regulation of ion pumps in ventricular myocyte

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Effects of cytosolic ATP on Ca(2+) sparks and SR Ca(2+) content in permeabilized cardiac myocytes

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Building with a scaffold: emerging strategies for high- to low-level cellular modeling

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The IkappaB-NF-kappaB signaling module: temporal control and selective gene activation

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Emergent properties of networks of biological signaling pathways

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Mechanisms of beta-adrenergic stimulation of cardiac Ca2+ channels revealed by discrete-time Markov analysis of slow gating

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Bioinformatics and cellular signaling

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Modeling beta-adrenergic control of cardiac myocyte contractility in silico

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Mechanistic systems models of cell signaling networks: a case study of myocyte adrenergic regulation.

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Molecular interactions between two long-QT syndrome gene products, HERG and KCNE2, rationalized by in vitro and in silico analysis

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21 January 2018

Genotype-phenotype correlation in the long-QT syndrome: gene-specific triggers for life-threatening arrhythmias.

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Requirement of a macromolecular signaling complex for beta adrenergic receptor modulation of the KCNQ1-KCNE1 potassium channel

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A multiaxial constitutive law for mammalian left ventricular myocardium in steady-state barium contracture or tetanus

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Three-dimensional analysis of regional cardiac function: a model of rabbit ventricular anatomy

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Sarcomere length changes in a 3D mathematical model of the pig ventricles

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Electromechanical model of cardiac resynchronization in the dilated failing heart with left bundle branch block

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Relationship between regional shortening and asynchronous electrical activation in a three-dimensional model of ventricular electromechanics.

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Homogeneity of cardiac contraction despite physiological asynchrony of depolarization: a model study.

1 reference

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Timing of depolarization and contraction in the paced canine left ventricle: model and experiment

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Drug-induced torsades de pointes and implications for drug development.

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Linking a genetic defect to its cellular phenotype in a cardiac arrhythmia

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21 January 2018

Identifiers

10.1196/ANNALS.1341.025

1 reference

Europe PubMed Central

12 August 2017

1 reference

Europe PubMed Central

12 August 2017

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