(Q36226027)

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Structure-activity relationship studies of flavonoids as potent inhibitors of human platelet 12-hLO, reticulocyte 15-hLO-1, and prostate epithelial 15-hLO-2.

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17869117%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

Structure-activity relationship studies of flavonoids as potent inhibitors of human platelet 12-hLO, reticulocyte 15-hLO-1, and prostate epithelial 15-hLO-2 (English)

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17869117%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

3

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Europe PubMed Central

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7 January 2020

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Yesseny Vasquez-Martinez

1

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17869117%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

Rachana V Ohri

2

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7 January 2020

Theodore R Holman

4

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7 January 2020

Silvia Sepúlveda-Boza

5

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7 January 2020

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22 August 2007

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7 January 2020

Bioorganic & Medicinal Chemistry

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Europe PubMed Central

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7 January 2020

15

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7 January 2020

23

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7 January 2020

7408-7425

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17869117%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

Baicalein is a potent in vitro inhibitor against both reticulocyte 15-human and platelet 12-human lipoxygenases.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2117341

1 October 2017

Novel human lipoxygenase inhibitors discovered using virtual screening with homology models

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2117341

1 October 2017

Overexpression of 12/15-lipoxygenase, an ortholog of human 15-lipoxygenase-1, in the prostate tumors of TRAMP mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2117341

1 October 2017

Peroxynitrite-induced neuronal apoptosis is mediated by intracellular zinc release and 12-lipoxygenase activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2117341

1 October 2017

A hierarchical approach to all-atom protein loop prediction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2117341

1 October 2017

Glide: a new approach for rapid, accurate docking and scoring. 2. Enrichment factors in database screening

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2117341

1 October 2017

Glide: a new approach for rapid, accurate docking and scoring. 1. Method and assessment of docking accuracy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2117341

1 October 2017

Mammalian arachidonate 15-lipoxygenases structure, function, and biological implications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2117341

1 October 2017

Arachidonate 12-lipoxygenases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2117341

1 October 2017

15-lipoxygenase-1: a prooxidant enzyme

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2117341

1 October 2017

Evidence that arachidonate 15-lipoxygenase 2 is a negative cell cycle regulator in normal prostate epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2117341

1 October 2017

Hinokitiol, a selective inhibitor of the platelet-type isozyme of arachidonate 12-lipoxygenase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2117341

1 October 2017

Structural basis for the positional specificity of lipoxygenases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2117341

1 October 2017

Lipoxygenases and atherosclerosis: protection versus pathogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2117341

1 October 2017

Differential characteristics of human 15-lipoxygenase isozymes and a novel splice variant of 15S-lipoxygenase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2117341

1 October 2017

Lipoxygenases: occurrence, functions, catalysis, and acquisition of substrate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2117341

1 October 2017

15-lipoxygenase-2 (15-LOX-2) is expressed in benign prostatic epithelium and reduced in prostate adenocarcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2117341

1 October 2017

12-Lipoxygenase: classification, possible therapeutic benefits from inhibition, and inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2117341

1 October 2017

Expression of 15-lipoxygenase-1 in human colorectal cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2117341

1 October 2017

Discovery of a second 15S-lipoxygenase in humans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2117341

1 October 2017

Inhibition of tumour growth by lipoxygenase inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2117341

1 October 2017

12-lipoxygenases and 12(S)-HETE: role in cancer metastasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2117341

1 October 2017

Mammalian lipoxygenases: molecular structures and functions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2117341

1 October 2017

Empirical scoring functions: I. The development of a fast empirical scoring function to estimate the binding affinity of ligands in receptor complexes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2117341

29 June 2018

New insights from spectroscopy into the structure/function relationships of lipoxygenases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2117341

29 June 2018

Criteria for the identification of non-redox inhibitors of 5-lipoxygenase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2117341

29 June 2018

Relative inhibitory potencies of flavonoids on 12-lipoxygenase of fish gill

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2117341

29 June 2018

Novel caffeic acid derivatives: extremely potent inhibitors of 12-lipoxygenase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2117341

29 June 2018

Pseudoperoxidase activity of 5-lipoxygenase stimulated by potent benzofuranol and N-hydroxyurea inhibitors of the lipoxygenase reaction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2117341

29 June 2018

Redox inactivation of human 15-lipoxygenase by marine-derived meroditerpenes and synthetic chromanes: archetypes for a unique class of selective and recyclable inhibitors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2117341

22 September 2018

Probing the activity differences of simple and complex brominated aryl compounds against 15-soybean, 15-human, and 12-human lipoxygenase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2117341

22 September 2018

Lipoxygenase inhibition by anadanthoflavone, a new flavonoid from the aerial parts of Anadenanthera colubrina

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2117341

22 September 2018

Inhibition of 15-lipoxygenases by flavonoids: structure-activity relations and mode of action

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2117341

22 September 2018

Exploring sponge-derived terpenoids for their potency and selectivity against 12-human, 15-human, and 15-soybean lipoxygenases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2117341

22 September 2018

2-Substituted 4-(thio)chromenone 6-O-sulfamates: potent inhibitors of human steroid sulfatase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2117341

22 September 2018

Structure-activity relationship studies of nordihydroguaiaretic acid inhibitors toward soybean, 12-human, and 15-human lipoxygenase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2117341

22 September 2018

Polyphenols of cocoa: inhibition of mammalian 15-lipoxygenase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2117341

22 September 2018

Probing sponge-derived terpenoids for human 15-lipoxygenase inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2117341

22 September 2018

2-arylalkyl-substituted anthracenones as inhibitors of 12-lipoxygenase enzymes. 1. Structure-activity relationships of the terminal aryl ring

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2117341

22 September 2018

Secretory phospholipase A2 and lipoprotein lipase enhance 15-lipoxygenase-induced enzymic and nonenzymic lipid peroxidation in low-density lipoproteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2117341

22 September 2018

Structure and mechanism of lipoxygenases.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2117341

22 September 2018

The lipoxygenase inhibitor 2-phenylmethyl-1-naphthol (DuP 654) is a 12(S)-hydroxyeicosatetraenoic acid receptor antagonist in the human epidermal cell line SCL-II.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2117341

22 September 2018

Selective inhibition of platelet lipoxygenase by esculetin

1 reference

https://pubmed.ncbi.nlm.nih.gov/17869117

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reductive inactivation of soybean lipoxygenase 1 by catechols: a possible mechanism for regulation of lipoxygenase activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/17869117

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduction of the active-site iron by potent inhibitors of lipoxygenases

1 reference

https://pubmed.ncbi.nlm.nih.gov/17869117

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

New isoflavonoids as inhibitors of porcine 5-lipoxygenase

1 reference

https://pubmed.ncbi.nlm.nih.gov/17869117

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antioxidant and radical scavenging effects of anthraquinones and anthrones

1 reference

https://pubmed.ncbi.nlm.nih.gov/17869117

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Panaxynol, a polyacetylene compound isolated from oriental medicines, inhibits mammalian lipoxygenases

1 reference

https://pubmed.ncbi.nlm.nih.gov/17869117

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A colorimetric method for the determination of lipoxygenase activity suitable for use in a high throughput assay format

1 reference

https://pubmed.ncbi.nlm.nih.gov/17869117

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Benzophenanthridine alkaloids of Chelidonium majus; I. Inhibition of 5- and 12-lipoxygenase by a non-redox mechanism

1 reference

https://pubmed.ncbi.nlm.nih.gov/17869117

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hydroperoxide assay with the ferric-xylenol orange complex

1 reference

https://pubmed.ncbi.nlm.nih.gov/17869117

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A convenient method for synthesizing 2-aryl-3-hydroxy-4-oxo-4H-1-benzopyrans or flavonols

1 reference

https://pubmed.ncbi.nlm.nih.gov/17869117

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

On the Role of the Crystal Environment in Determining Protein Side-chain Conformations

1 reference

https://pubmed.ncbi.nlm.nih.gov/17869117

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.BMC.2007.07.036

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17869117%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

release_lxih2n2ij5hgrmieiofqh4rhku

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https://api.fatcat.wiki/v0/release/lxih2n2ij5hgrmieiofqh4rhku

24 November 2022

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7 January 2020

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17869117%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

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