(Q36226806)

12 August 2017

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title

Non-viral vectors for gene therapy: clinical trials in cardiovascular disease (English)

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12 August 2017

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Pinak B Shah

1

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12 August 2017

Douglas W Losordo

series ordinal

2

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12 August 2017

publication date

1 January 2005

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12 August 2017

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12 August 2017

volume

54

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12 August 2017

page(s)

339-361

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Vascular endothelial growth factor in ocular fluid of patients with diabetic retinopathy and other retinal disorders

12 August 2017

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Constitutive expression of phVEGF165 after intramuscular gene transfer promotes collateral vessel development in patients with critical limb ischemia

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7 January 2021

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7 January 2021

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7 January 2021

Naked plasmid DNA encoding fibroblast growth factor type 1 for the treatment of end-stage unreconstructible lower extremity ischemia: preliminary results of a phase I trial

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7 January 2021

Current diagnostic techniques of assessing myocardial viability in patients with hibernating and stunned myocardium

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7 January 2021

Intraoperative multiplane transesophageal echocardiography for guiding direct myocardial gene transfer of vascular endothelial growth factor in patients with refractory angina pectoris

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7 January 2021

Isolation of a tumor factor responsible for angiogenesis

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7 January 2021

Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium

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7 January 2021

Electromechanical characterization of chronic myocardial infarction in the canine coronary occlusion model

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7 January 2021

Intracoronary gene transfer of fibroblast growth factor-5 increases blood flow and contractile function in an ischemic region of the heart

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7 January 2021

Angiogenic Gene Therapy (AGENT) trial in patients with stable angina pectoris

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7 January 2021

VEGF improves myocardial blood flow but produces EDRF-mediated hypotension in porcine hearts

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7 January 2021

Safety and Feasibility of Catheter-Based Local Intracoronary Vascular Endothelial Growth Factor Gene Transfer in the Prevention of Postangioplasty and In-Stent Restenosis and in the Treatment of Chronic Myocardial Ischemia

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7 January 2021

The VIVA trial: Vascular endothelial growth factor in Ischemia for Vascular Angiogenesis

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7 January 2021

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7 January 2021

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7 January 2021

Treatment of thromboangiitis obliterans (Buerger's disease) by intramuscular gene transfer of vascular endothelial growth factor: preliminary clinical results

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7 January 2021

Assessment of risks associated with cardiovascular gene therapy in human subjects

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7 January 2021

Arterial gene therapy for therapeutic angiogenesis in patients with peripheral artery disease

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7 January 2021

Hyperplasia of lymphatic vessels in VEGF-C transgenic mice

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7 January 2021

Vascular endothelial growth factor(165) gene transfer augments circulating endothelial progenitor cells in human subjects

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7 January 2021

VEGF gene transfer mobilizes endothelial progenitor cells in patients with inoperable coronary disease

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7 January 2021

Direct intramyocardial plasmid vascular endothelial growth factor-A165 gene therapy in patients with stable severe angina pectoris A randomized double-blind placebo-controlled study: the Euroinject One trial

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7 January 2021

Local perivascular delivery of basic fibroblast growth factor in patients undergoing coronary bypass surgery: results of a phase I randomized, double-blind, placebo-controlled trial

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7 January 2021

Therapeutic angiogenesis with recombinant fibroblast growth factor-2 for intermittent claudication (the TRAFFIC study): a randomised trial

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7 January 2021

Focal angiogen therapy using intramyocardial delivery of an adenovirus vector coding for vascular endothelial growth factor 121.

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7 January 2021

Vascular endothelial growth factor is a secreted angiogenic mitogen

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7 January 2021

Post-transcriptional regulation of vascular endothelial growth factor by hypoxia

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7 January 2021

Use of the rabbit ear artery to serially assess foreign protein secretion after site-specific arterial gene transfer in vivo. Evidence that anatomic identification of successful gene transfer may underestimate the potential magnitude of transgene ex

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7 January 2021

Phase 1/2 placebo-controlled, double-blind, dose-escalating trial of myocardial vascular endothelial growth factor 2 gene transfer by catheter delivery in patients with chronic myocardial ischemia

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7 January 2021

Gene therapy for myocardial angiogenesis: initial clinical results with direct myocardial injection of phVEGF165 as sole therapy for myocardial ischemia

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7 January 2021

Biologic bypass with the use of adenovirus-mediated gene transfer of the complementary deoxyribonucleic acid for vascular endothelial growth factor 121 improves myocardial perfusion and function in the ischemic porcine heart

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7 January 2021

Endovascular brachytherapy for prophylaxis of restenosis after femoropopliteal angioplasty : results of a prospective randomized study

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7 January 2021

Angiogenesis inhibitors endostatin or TNP-470 reduce intimal neovascularization and plaque growth in apolipoprotein E-deficient mice.

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7 January 2021

Hypoxia induces vascular endothelial growth factor in cultured human endothelial cells

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7 January 2021

Magnetic resonance mapping demonstrates benefits of VEGF-induced myocardial angiogenesis

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7 January 2021

Coronary angiogenesis: detection in vivo with MR imaging sensitive to collateral neocirculation--preliminary study in pigs

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7 January 2021

Induction of neoangiogenesis in ischemic myocardium by human growth factors: first clinical results of a new treatment of coronary heart disease

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7 January 2021

Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice

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7 January 2021

Mechanism of impaired myocardial function during progressive coronary stenosis in conscious pigs. Hibernation versus stunning?

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7 January 2021

Pharmacological treatment of coronary artery disease with recombinant fibroblast growth factor-2: double-blind, randomized, controlled clinical trial

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7 January 2021

Gene therapy with vascular endothelial growth factor for inoperable coronary artery disease

1 reference

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7 January 2021

Arterial gene transfer of acidic fibroblast growth factor for therapeutic angiogenesis in vivo: critical role of secretion signal in use of naked DNA.

1 reference

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7 January 2021

Therapeutic angiogenesis following arterial gene transfer of vascular endothelial growth factor in a rabbit model of hindlimb ischemia

1 reference

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7 January 2021

Leakage-resistant blood vessels in mice transgenically overexpressing angiopoietin-1

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2805%2954014-8

7 January 2021

Direct intramuscular gene transfer of naked DNA encoding vascular endothelial growth factor augments collateral development and tissue perfusion

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2805%2954014-8

7 January 2021

Therapeutic angiogenesis with recombinant fibroblast growth factor-2 improves stress and rest myocardial perfusion abnormalities in patients with severe symptomatic chronic coronary artery disease

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2805%2954014-8

7 January 2021

Effects of a single intracoronary injection of basic fibroblast growth factor in stable angina pectoris

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2805%2954014-8

7 January 2021

Catheter-based myocardial gene transfer utilizing nonfluoroscopic electromechanical left ventricular mapping.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2805%2954014-8

7 January 2021

Left ventricular electromechanical mapping to assess efficacy of phVEGF(165) gene transfer for therapeutic angiogenesis in chronic myocardial ischemia

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2805%2954014-8

7 January 2021

Randomized, single-blind, placebo-controlled pilot study of catheter-based myocardial gene transfer for therapeutic angiogenesis using left ventricular electromechanical mapping in patients with chronic myocardial ischemia

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2805%2954014-8

7 January 2021

Passivation of metallic stents after arterial gene transfer of phVEGF165 inhibits thrombus formation and intimal thickening

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2805%2954014-8

7 January 2021

Stent endothelialization. Time course, impact of local catheter delivery, feasibility of recombinant protein administration, and response to cytokine expedition

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2805%2954014-8

7 January 2021

Vascular endothelial growth factor/vascular permeability factor augments nitric oxide release from quiescent rabbit and human vascular endothelium.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2805%2954014-8

7 January 2021

Functional upregulation of the vascular endothelial growth factor receptor KDR by hypoxia

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2805%2954014-8

7 January 2021

Hibernating myocardium.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2805%2954014-8

7 January 2021

Vascular endothelial growth factor-C (VEGF-C/VEGF-2) promotes angiogenesis in the setting of tissue ischemia

1 reference

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7 January 2021

Cellular immunity to viral antigens limits E1-deleted adenoviruses for gene therapy

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7 January 2021

Pituitary follicular cells secrete a novel heparin-binding growth factor specific for vascular endothelial cells

1 reference

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7 January 2021

10.1016/S0065-2660(05)54014-8

Identifiers

DOI

1 reference

12 August 2017

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