(Q36240746)

13 August 2017

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title

Clinical pharmacokinetics of telithromycin, the first ketolide antibacterial (English)

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13 August 2017

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Jun Shi

1

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13 August 2017

Guy Montay

series ordinal

2

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13 August 2017

Vijay O Bhargava

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3

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13 August 2017

language of work or name

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1 January 2005

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Clinical Pharmacokinetics

13 August 2017

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13 August 2017

44

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13 August 2017

9

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13 August 2017

915-934

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https://scigraph.springernature.com/pub.10.2165/00003088-200544090-00003

13 August 2017

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cites work

In-vitro activity of ketolides against mycoplasmas

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12 December 2020

Lung concentrations of telithromycin after oral dosing

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12 December 2020

In vitro and in vivo intraleukocytic accumulation of azithromycin (CP-62, 993) and its influence on ex vivo leukocyte chemiluminescence

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12 December 2020

Pharmacokinetics and safety of the ketolide telithromycin in patients with renal impairment

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12 December 2020

Metabolism of cyclosporin A. IV. Purification and identification of the rifampicin-inducible human liver cytochrome P-450 (cyclosporin A oxidase) as a product of P450IIIA gene subfamily

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12 December 2020

Midazolam should be avoided in patients receiving the systemic antimycotics ketoconazole or itraconazole.

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12 December 2020

Lack of effect of food on the bioavailability of a new ketolide antibacterial, telithromycin

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12 December 2020

Effect of clarithromycin on renal excretion of digoxin: interaction with P-glycoprotein

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12 December 2020

In vitro activity of a new ketolide antibiotic, HMR 3647, against Chlamydia pneumoniae.

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12 December 2020

The conduct of in vitro and in vivo drug-drug interaction studies: a Pharmaceutical Research and Manufacturers of America (PhRMA) perspective

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12 December 2020

Structures of ketolides and macrolides determine their mode of interaction with the ribosomal target site

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12 December 2020

Simvastatin but not pravastatin is very susceptible to interaction with the CYP3A4 inhibitor itraconazole.

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12 December 2020

Differentiation of intestinal and hepatic cytochrome P450 3A activity with use of midazolam as an in vivo probe: effect of ketoconazole.

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12 December 2020

In vitro activity of telithromycin (HMR3647), a new ketolide, against clinical isolates of Mycoplasma pneumoniae in Japan

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12 December 2020

Inactivation of Digoxin by the Gut Flora: Reversal by Antibiotic Therapy

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12 December 2020

Evolving resistance patterns in community-acquired respiratory tract pathogens: first results from the PROTEKT global surveillance study. Prospective Resistant Organism Tracking and Epidemiology for the Ketolide Telithromycin.

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12 December 2020

Pharmacokinetics and comparative effects of telithromycin (HMR 3647) and clarithromycin on the oropharyngeal and intestinal microflora

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12 December 2020

Synthesis and antibacterial activity of HMR 3647 a new ketolide highly potent against erythromycin-resistant and susceptible pathogens

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12 December 2020

Contribution of increased oral bioavailability and reduced nonglomerular renal clearance of digoxin to the digoxin-clarithromycin interaction

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12 December 2020

Comparative activity of telithromycin against macrolide-resistant isolates of Streptococcus pneumoniae: results of two years of the PROTEKT surveillance study

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12 December 2020

Structure-activity relationships of ketolides vs. macrolides

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12 December 2020

Macrolide-ketolide inhibition of MLS-resistant ribosomes is improved by alternative drug interaction with domain II of 23S rRNA

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12 December 2020

Grapefruit juice-simvastatin interaction: effect on serum concentrations of simvastatin, simvastatin acid, and HMG-CoA reductase inhibitors

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12 December 2020

Experimental estimation of the role of P-Glycoprotein in the pharmacokinetic behaviour of telithromycin, a novel ketolide, in comparison with roxithromycin and other macrolides using the Caco-2 cell model

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12 December 2020

In vitro development of resistance to telithromycin (HMR 3647), four macrolides, clindamycin, and pristinamycin in Streptococcus pneumoniae

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12 December 2020

Erythromycin, clarithromycin, and azithromycin: are the differences real?

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12 December 2020

Activity of telithromycin, a new ketolide antibacterial, against atypical and intracellular respiratory tract pathogens

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12 December 2020

The role of intestinal P-glycoprotein in the interaction of digoxin and rifampin

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12 December 2020

Comparative in vitro activity of telithromycin and beta-lactam antimicrobials against bacterial pathogens from community-acquired respiratory tract infections: data from the first year of PROTEKT (1999-2000).

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12 December 2020

Penetration of clarithromycin into lung tissues from patients undergoing lung resection

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12 December 2020

Pharmacokinetic-pharmacodynamic consequences and clinical relevance of cytochrome P450 3A4 inhibition

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12 December 2020

Pharmacokinetics of the ketolide telithromycin after single and repeated doses in patients with hepatic impairment

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12 December 2020

Pharmacodynamic analysis of the microbiological efficacy of telithromycin in patients with community-acquired pneumonia

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12 December 2020

Intrapulmonary pharmacokinetics of clarithromycin and of erythromycin

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12 December 2020

Effect of ketoconazole on the pharmacokinetics and safety of telithromycin and clarithromycin in older subjects with renal impairment

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12 December 2020

The effect of rifampin treatment on intestinal expression of human MRP transporters

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12 December 2020

Characterization of hepatic cytochrome p4503A activity in patients with end-stage renal disease

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12 December 2020

Penetration of telithromycin (HMR 3647), a new ketolide antimicrobial, into inflammatory blister fluid following oral administration

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12 December 2020

In vitro activity of the ketolide HMR 3647 (RU 6647) for Legionella spp., its pharmacokinetics in guinea pigs, and use of the drug to treat guinea pigs with Legionella pneumophila pneumonia.

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12 December 2020

Pharmacokinetics and absolute oral bioavailability of an 800-mg oral dose of telithromycin in healthy young and elderly volunteers

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12 December 2020

The influence of cisapride and clarithromycin on QT intervals in healthy volunteers.

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12 December 2020

The macrolide-ketolide antibiotic binding site is formed by structures in domains II and V of 23S ribosomal RNA.

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12 December 2020

Effects of itraconazole or grapefruit juice on the pharmacokinetics of telithromycin

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12 December 2020

Modulators and substrates of P-glycoprotein and cytochrome P4503A coordinately up-regulate these proteins in human colon carcinoma cells.

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12 December 2020

Terfenadine-ketoconazole interaction. Pharmacokinetic and electrocardiographic consequences

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12 December 2020

Interaction of azithromycin and human phagocytic cells. Uptake of the antibiotic and the effect on the survival of ingested bacteria in phagocytes

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12 December 2020

Pharmacokinetics of the new ketolide telithromycin (HMR 3647) administered in ascending single and multiple doses

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12 December 2020

Azithromycin concentrations at the sites of pulmonary infection

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12 December 2020

The contribution of intestinal and hepatic CYP3A to the interaction between midazolam and clarithromycin.

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12 December 2020

Bronchopulmonary disposition of the ketolide telithromycin (HMR 3647).

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12 December 2020

10.2165/00003088-200544090-00003

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DOI

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Dimensions Publication ID

13 August 2017

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