(Q36248054)

13 August 2017

1 reference

title

G-protein-coupled receptor deorphanizations (English)

1 reference

G protein-coupled receptor

13 August 2017

main subject

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author name string

Yumiko Saito

series ordinal

1

1 reference

13 August 2017

Olivier Civelli

series ordinal

2

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13 August 2017

publication date

1 January 2005

1 reference

International Review of Neurobiology

13 August 2017

published in

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13 August 2017

volume

65

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13 August 2017

page(s)

179-209

1 reference

Molecular cloning and characterization of the human anaphylatoxin C3a receptor

13 August 2017

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Human urotensin-II is a potent vasoconstrictor and agonist for the orphan receptor GPR14

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Sphingosine 1-phosphate-induced cell proliferation, survival, and related signaling events mediated by G protein-coupled receptors Edg3 and Edg5

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7 January 2021

Characterization of a novel subtype of human G protein-coupled receptor for lysophosphatidic acid

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7 January 2021

Identification of melanin concentrating hormone (MCH) as the natural ligand for the orphan somatostatin-like receptor 1 (SLC-1).

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7 January 2021

Neuropeptide W acts in brain to control prolactin, corticosterone, and growth hormone release

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7 January 2021

Characterization of an orphan G protein-coupled receptor localized in the dorsal root ganglia reveals adenine as a signaling molecule

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7 January 2021

Association of polymorphisms in GPR10, the gene encoding the prolactin-releasing peptide receptor with blood pressure, but not obesity, in a U.K. Caucasian population

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7 January 2021

The melanin-concentrating hormone system of the rat brain: an immuno- and hybridization histochemical characterization

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7 January 2021

Identification and characterisation of GPR100 as a novel human G‐protein‐coupled bradykinin receptor

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7 January 2021

Trace amines: identification of a family of mammalian G protein-coupled receptors

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7 January 2021

The orphan G protein-coupled receptor GPR40 is activated by medium and long chain fatty acids

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The Orphan G protein-coupled receptors GPR41 and GPR43 are activated by propionate and other short chain carboxylic acids

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7 January 2021

Cloning and expression of a rat D2 dopamine receptor cDNA

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The orphan receptor C5L2 has high affinity binding sites for complement fragments C5a and C5a des-Arg(74)

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7 January 2021

Melanin-concentrating hormone is the cognate ligand for the orphan G-protein-coupled receptor SLC-1

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7 January 2021

A G protein-coupled receptor for UDP-glucose

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7 January 2021

Narcolepsy in orexin knockout mice: molecular genetics of sleep regulation

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Prolactin-releasing peptide-immunoreactivity in A1 and A2 noradrenergic neurons of the rat medulla.

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7 January 2021

Targeted disruption of the melanin-concentrating hormone receptor-1 results in hyperphagia and resistance to diet-induced obesity.

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7 January 2021

Novel neurotransmitters as natural ligands of orphan G-protein-coupled receptors

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7 January 2021

GPCR deorphanizations: the novel, the known and the unexpected transmitters

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7 January 2021

5-HT1A receptor immunoreactivity in hypothalamic neurons involved in body weight control

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7 January 2021

Substitution of three amino acids switches receptor specificity of Gq alpha to that of Gi alpha

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7 January 2021

Peptidergic modulation of intrathalamic circuit activity in vitro: actions of cholecystokinin.

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7 January 2021

The endogenous ligand Stunted of the GPCR Methuselah extends lifespan in Drosophila

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7 January 2021

Acute and chronic administration of melanin-concentrating hormone enhances food intake and body weight in Wistar and Sprague-Dawley rats

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7 January 2021

Drug discovery: a historical perspective

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7 January 2021

Signal transduction via P2-purinergic receptors for extracellular ATP and other nucleotides

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7 January 2021

Receptor for the pain modulatory neuropeptides FF and AF is an orphan G protein-coupled receptor

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7 January 2021

The genomic clone G-21 which resembles a beta-adrenergic receptor sequence encodes the 5-HT1A receptor

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7 January 2021

Receptor for motilin identified in the human gastrointestinal system

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7 January 2021

Association Between Physical Activity and Blood Pressure Is Modified by Variants in the G-Protein Coupled Receptor 10

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7 January 2021

Identification of neuromedin U as the cognate ligand of the orphan G protein-coupled receptor FM-3.

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7 January 2021

Identification of a neuropeptide modified with bromine as an endogenous ligand for GPR7

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7 January 2021

A new peptidic ligand and its receptor regulating adrenal function in rats

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7 January 2021

EDG6, a novel G-protein-coupled receptor related to receptors for bioactive lysophospholipids, is specifically expressed in lymphoid tissue

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7 January 2021

The melanin-concentrating hormone receptor couples to multiple G proteins to activate diverse intracellular signaling pathways

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7 January 2021

Citric acid cycle intermediates as ligands for orphan G-protein-coupled receptors

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7 January 2021

The distribution of the mRNA and protein products of the melanin-concentrating hormone (MCH) receptor gene, slc-1, in the central nervous system of the rat.

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7 January 2021

A prolactin-releasing peptide in the brain

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7 January 2021

New neuropeptides containing carboxy-terminal RFamide and their receptor in mammals

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7 January 2021

Identification of a novel human eicosanoid receptor coupled to G(i/o)

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7 January 2021

Activation of orphan receptors by the hormone relaxin

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7 January 2021

A novel function of prolactin-releasing peptide in the control of growth hormone via secretion of somatostatin from the hypothalamus

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7 January 2021

Identification of a molecular target of psychosine and its role in globoid cell formation

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7 January 2021

Identification and characterization of a cell-surface receptor, P2Y15, for AMP and adenosine

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7 January 2021

Targeted disruption of GPR7, the endogenous receptor for neuropeptides B and W, leads to metabolic defects and adult-onset obesity

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7 January 2021

Characterization of MCH-mediated obesity in mice

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7 January 2021

Cutting edge: identification of the orphan receptor G-protein-coupled receptor 2 as CCR10, a specific receptor for the chemokine ESkine

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7 January 2021

Gonadal regulation of PrRP mRNA expression in the nucleus tractus solitarius and ventral and lateral reticular nuclei of the rat.

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7 January 2021

GABA(B)-receptor subtypes assemble into functional heteromeric complexes.

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7 January 2021

Characterization of melanin-concentrating hormone in chum salmon pituitaries.

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7 January 2021

Purification and identification of neuromedin U as an endogenous ligand for an orphan receptor GPR66 (FM3).

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7 January 2021

Ghrelin is a growth-hormone-releasing acylated peptide from stomach

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7 January 2021

Is Galpha16 the optimal tool for fishing ligands of orphan G-protein-coupled receptors?

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7 January 2021

Targeted disruption of the orphanin FQ/nociceptin gene increases stress susceptibility and impairs stress adaptation in mice

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7 January 2021

Melanin-concentrating hormone-1 receptor antagonism decreases feeding by reducing meal size

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7 January 2021

Cloning of the rat brain cDNA encoding for the SLC-1 G protein-coupled receptor reveals the presence of an intron in the gene

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7 January 2021

PRL-releasing peptide reduces food intake and may mediate satiety signaling.

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7 January 2021

Alternative role for prolactin-releasing peptide in the regulation of food intake.

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7 January 2021

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7 January 2021

Sphingosine-1-phosphate as a ligand for the G protein-coupled receptor EDG-1

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7 January 2021

The receptor for the orexigenic peptide melanin-concentrating hormone is a G-protein-coupled receptor

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7 January 2021

Proenkephalin A gene products activate a new family of sensory neuron--specific GPCRs

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7 January 2021

Tools for investigating functional interactions between ligands and G-protein-coupled receptors

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7 January 2021

Selective amplification and cloning of four new members of the G protein-coupled receptor family

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7 January 2021

Identification of Relaxin-3/INSL7 as a Ligand for GPCR142

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7 January 2021

Prolactin-releasing peptide (PrRP) promotes awakening and suppresses absence seizures

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7 January 2021

Cloning and functional expression of the human histamine H3 receptor

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7 January 2021

Melanin-concentrating hormone overexpression in transgenic mice leads to obesity and insulin resistance

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7 January 2021

Proton-sensing G-protein-coupled receptors

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7 January 2021

Characterization of the human cysteinyl leukotriene CysLT1 receptor

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7 January 2021

G-protein-coupled receptors and signaling networks: emerging paradigms.

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7 January 2021

Melanin-concentrating hormone 1 receptor-deficient mice are lean, hyperactive, and hyperphagic and have altered metabolism

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7 January 2021

Immunocytochemical localization of prolactin-releasing peptide in the rat brain

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7 January 2021

Identification of membrane-type receptor for bile acids (M-BAR)

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7 January 2021

Isolation and identification of EG-VEGF/prokineticins as cognate ligands for two orphan G-protein-coupled receptors

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7 January 2021

Stimulation of corticotropin-releasing hormone-mediated adrenocorticotropin secretion by central administration of prolactin-releasing peptide in rats

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7 January 2021

Stimulation of prolactin release by prolactin-releasing peptide in rats.

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7 January 2021

RAMPs regulate the transport and ligand specificity of the calcitonin-receptor-like receptor

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7 January 2021

Isolation and structure of the endogenous agonist of opioid receptor-like ORL1 receptor

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7 January 2021

A role for neuropeptide W in the regulation of feeding behavior

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7 January 2021

Cloning of a novel G protein-coupled receptor, SLT, a subtype of the melanin-concentrating hormone receptor

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7 January 2021

A role for ghrelin in the central regulation of feeding

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7 January 2021

Identification of the natural ligand of an orphan G-protein-coupled receptor involved in the regulation of vasoconstriction

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7 January 2021

Molecular cloning and characterization of a novel type of histamine receptor preferentially expressed in leukocytes

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7 January 2021

The Cloning and Chromosomal Mapping of Two Novel Human Opioid-Somatostatin-like Receptor Genes, GPR7 and GPR8, Expressed in Discrete Areas of the Brain

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7 January 2021

Isolation and cDNA cloning of a novel galanin-like peptide (GALP) from porcine hypothalamus

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7 January 2021

Metastasis suppressor gene KiSS-1 encodes peptide ligand of a G-protein-coupled receptor

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7 January 2021

Melanin-concentrating hormone: from fish skin to skinny mammals

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7 January 2021

A role for melanin-concentrating hormone in the central regulation of feeding behaviour

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7 January 2021

Orphanin FQ: a neuropeptide that activates an opioidlike G protein-coupled receptor.

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7 January 2021

MrgX2 is a high potency cortistatin receptor expressed in dorsal root ganglion

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7 January 2021

Inhibition of Caenorhabditis elegans social feeding by FMRFamide-related peptide activation of NPR-1.

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7 January 2021

Anatomical distribution of prolactin-releasing peptide and its receptor suggests additional functions in the central nervous system and periphery

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7 January 2021

Melanin-concentrating hormone acutely stimulates feeding, but chronic administration has no effect on body weight

1 reference

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7 January 2021

Identification and characterization of a second melanin-concentrating hormone receptor, MCH-2R

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7 January 2021

Expression of the melanin-concentrating hormone (MCH) receptor mRNA in the rat brain

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7 January 2021

Molecular characterization of the melanin-concentrating-hormone receptor

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7 January 2021

Fishy tales of prolactin-releasing peptide

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https://api.crossref.org/works/10.1016%2FS0074-7742%2804%2965007-0

7 January 2021

Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior

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7 January 2021

A novel action of the newly described prolactin-releasing peptides: cardiovascular regulation

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7 January 2021

Prolactin-releasing peptide releases corticotropin-releasing hormone and increases plasma adrenocorticotropin via the paraventricular nucleus of the hypothalamus

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2804%2965007-0

7 January 2021

Melanin-concentrating hormone is a critical mediator of the leptin-deficient phenotype

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https://api.crossref.org/works/10.1016%2FS0074-7742%2804%2965007-0

7 January 2021

Chronic MCH-1 receptor modulation alters appetite, body weight and adiposity in rats

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7 January 2021

Mice lacking melanin-concentrating hormone are hypophagic and lean

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2804%2965007-0

7 January 2021

Identification of neuropeptide W as the endogenous ligand for orphan G-protein-coupled receptors GPR7 and GPR8

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2804%2965007-0

7 January 2021

Isolation and identification of melanin-concentrating hormone as the endogenous ligand of the SLC-1 receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2804%2965007-0

7 January 2021

Functional Assays for Identifying Ligands at Orphan G Protein-Coupled Receptors

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7 January 2021

Neuromedin U is a potent agonist at the orphan G protein-coupled receptor FM3

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2804%2965007-0

7 January 2021

T-226296: a novel, orally active and selective melanin-concentrating hormone receptor antagonist

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7 January 2021

Melanin-concentrating hormone receptor subtypes 1 and 2: species-specific gene expression

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https://api.crossref.org/works/10.1016%2FS0074-7742%2804%2965007-0

7 January 2021

Characterization of a family of endogenous neuropeptide ligands for the G protein-coupled receptors GPR7 and GPR8

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2804%2965007-0

7 January 2021

Isolation and characterization of a novel endogenous peptide ligand for the human APJ receptor

1 reference

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7 January 2021

TIP39: a new neuropeptide and PTH2-receptor agonist from hypothalamus

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7 January 2021

Sequence and tissue distribution of a candidate G-coupled receptor cloned from rat hypothalamus

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7 January 2021

Molecular identification of high and low affinity receptors for nicotinic acid

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7 January 2021

The identification of ligands at orphan G-protein coupled receptors

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7 January 2021

Sphingosylphosphorylcholine is a ligand for ovarian cancer G-protein-coupled receptor 1.

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7 January 2021

Cloning of adiponectin receptors that mediate antidiabetic metabolic effects

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7 January 2021

A G-protein-coupled receptor for leukotriene B4 that mediates chemotaxis

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7 January 2021

ADP is the cognate ligand for the orphan G protein-coupled receptor SP1999

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7 January 2021

Sphingosylphosphorylcholine and lysophosphatidylcholine are ligands for the G protein-coupled receptor GPR4

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7 January 2021

Prokineticin 2 transmits the behavioural circadian rhythm of the suprachiasmatic nucleus

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7 January 2021

The hypocretins: hypothalamus-specific peptides with neuroexcitatory activity

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https://api.crossref.org/works/10.1016%2FS0074-7742%2804%2965007-0

7 January 2021

Techniques: Cardiovascular pharmacology and drug discovery in the 21st century

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2804%2965007-0

7 January 2021

Edg-2/Vzg-1 couples to the yeast pheromone response pathway selectively in response to lysophosphatidic acid

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2804%2965007-0

7 January 2021

Identification and characterization of single-nucleotide polymorphisms in MCH-R1 and MCH-R2.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2804%2965007-0

7 January 2021

Free fatty acids regulate insulin secretion from pancreatic beta cells through GPR40.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2804%2965007-0

7 January 2021

RETRACTED: Lysophosphatidylcholine as a ligand for the immunoregulatory receptor G2A.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2804%2965007-0

7 January 2021

Identification of an orphan receptor gene as a type 1 calcitonin gene-related peptide receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2804%2965007-0

7 January 2021

Emerging roles for orphan G-protein-coupled receptors in the cardiovascular system

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2804%2965007-0

7 January 2021

Characterization of a human gene related to genes encoding somatostatin receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2804%2965007-0

7 January 2021

Identification and molecular characterization of two closely related G protein-coupled receptors activated by prokineticins/endocrine gland vascular endothelial growth factor

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2804%2965007-0

7 January 2021

Identification of Relaxin-3/INSL7 as an Endogenous Ligand for the Orphan G-protein-coupled Receptor GPCR135

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2804%2965007-0

7 January 2021

Identification of a G protein-coupled receptor specifically responsive to beta-alanine

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2804%2965007-0

7 January 2021

The Edg family G protein-coupled receptors for lysophospholipids: their signaling properties and biological activities

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2804%2965007-0

7 January 2021

The G protein-coupled receptor repertoires of human and mouse

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2804%2965007-0

7 January 2021

Short-chain fatty acids stimulate leptin production in adipocytes through the G protein-coupled receptor GPR41

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2804%2965007-0

7 January 2021

Neuropeptide S: a neuropeptide promoting arousal and anxiolytic-like effects

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2804%2965007-0

7 January 2021

Mice lacking the M3 muscarinic acetylcholine receptor are hypophagic and lean.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2804%2965007-0

7 January 2021

10.1016/S0074-7742(04)65007-0

Identifiers

DOI

1 reference

13 August 2017

1 reference