(Q36260008)

13 August 2017

1 reference

title

Hypocretins (orexins) and sleep-wake disorders (English)

1 reference

13 August 2017

Christian R Baumann

1

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13 August 2017

Claudio L Bassetti

series ordinal

2

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13 August 2017

publication date

1 October 2005

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13 August 2017

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13 August 2017

volume

4

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13 August 2017

issue

10

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13 August 2017

page(s)

673-682

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Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior

13 August 2017

cites work

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7 January 2021

The hypocretins: hypothalamus-specific peptides with neuroexcitatory activity

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7 January 2021

Hypocretin (orexin) deficiency in human narcolepsy.

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7 January 2021

Neocortical and caudate projections of intralaminar thalamic neurons and their synaptic excitation from midbrain reticular core

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7 January 2021

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7 January 2021

Identification of sleep-promoting neurons in vitro.

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7 January 2021

Ventrolateral preoptic nucleus contains sleep-active, galaninergic neurons in multiple mammalian species.

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7 January 2021

GABA-mediated control of hypocretin- but not melanin-concentrating hormone-immunoreactive neurones during sleep in rats

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7 January 2021

Distribution of orexin receptor mRNA in the rat brain.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2805%2970196-4

7 January 2021

Orexin A activates locus coeruleus cell firing and increases arousal in the rat.

1 reference

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7 January 2021

Orexin A excites serotonergic neurons in the dorsal raphe nucleus of the rat.

1 reference

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7 January 2021

Orexin/hypocretin excites the histaminergic neurons of the tuberomammillary nucleus.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2805%2970196-4

7 January 2021

Differential expression of orexin receptors 1 and 2 in the rat brain.

1 reference

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7 January 2021

Hypocretin/Orexin excites hypocretin neurons via a local glutamate neuron-A potential mechanism for orchestrating the hypothalamic arousal system

1 reference

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7 January 2021

Neurons containing hypocretin (orexin) project to multiple neuronal systems

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2805%2970196-4

7 January 2021

Distribution and quantification of immunoreactive orexin A in rat tissues.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2805%2970196-4

7 January 2021

Orexin (hypocretin)/dynorphin neurons control GABAergic inputs to tuberomammillary neurons

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2805%2970196-4

7 January 2021

Narp immunostaining of human hypocretin (orexin) neurons: loss in narcolepsy

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2805%2970196-4

7 January 2021

Concomitant loss of dynorphin, NARP, and orexin in narcolepsy

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2805%2970196-4

7 January 2021

The wake-promoting hypocretin/orexin neurons change their response to noradrenaline after sleep deprivation.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2805%2970196-4

7 January 2021

Regulation of orexin neurons by the monoaminergic and cholinergic systems.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2805%2970196-4

7 January 2021

Serotonergic regulation of the orexin/hypocretin neurons through the 5-HT1A receptor.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2805%2970196-4

7 January 2021

Direct and indirect inhibition by catecholamines of hypocretin/orexin neurons.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2805%2970196-4

7 January 2021

Fos expression in orexin neurons varies with behavioral state.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2805%2970196-4

7 January 2021

Fos immunoreactivity in hypocretin-synthesizing and hypocretin-1 receptor-expressing neurons: effects of diurnal and nocturnal spontaneous waking, stress and hypocretin-1 administration

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2805%2970196-4

7 January 2021

Circadian and Homeostatic Regulation of Hypocretin in a Primate Model: Implications for the Consolidation of Wakefulness

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2805%2970196-4

7 January 2021

Discharge of identified orexin/hypocretin neurons across the sleep-waking cycle.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2805%2970196-4

7 January 2021

Hypocretin-1 modulates rapid eye movement sleep through activation of locus coeruleus neurons.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2805%2970196-4

7 January 2021

Wake-promoting and sleep-suppressing actions of hypocretin (orexin): basal forebrain sites of action

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2805%2970196-4

7 January 2021

Selective action of orexin (hypocretin) on nonspecific thalamocortical projection neurons.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2805%2970196-4

7 January 2021

Arousal effect of orexin A depends on activation of the histaminergic system

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2805%2970196-4

7 January 2021

The wake-promoting hypocretin-orexin neurons are in an intrinsic state of membrane depolarization.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2805%2970196-4

7 January 2021

Release of hypocretin (orexin) during waking and sleep states.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2805%2970196-4

7 January 2021

Sleep-waking discharge patterns of neurons recorded in the rat perifornical lateral hypothalamic area.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2805%2970196-4

7 January 2021

Hypocretin/orexin and sleep: implications for the pathophysiology and diagnosis of narcolepsy

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2805%2970196-4

7 January 2021

The sleep switch: hypothalamic control of sleep and wakefulness

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2805%2970196-4

7 January 2021

Behavioral state instability in orexin knock-out mice.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2805%2970196-4

7 January 2021

The suprachiasmatic nucleus projects to posterior hypothalamic arousal systems.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2805%2970196-4

7 January 2021

Fluctuation of extracellular hypocretin-1 (orexin A) levels in the rat in relation to the light-dark cycle and sleep-wake activities.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2805%2970196-4

7 January 2021

Paradoxical timing of the circadian rhythm of sleep propensity serves to consolidate sleep and wakefulness in humans

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2805%2970196-4

7 January 2021

Lesions of the suprachiasmatic nucleus eliminate the daily rhythm of hypocretin-1 release.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2805%2970196-4

7 January 2021

Convergence of circadian and sleep regulatory mechanisms on hypocretin-1.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2805%2970196-4

7 January 2021

Increased hypocretin-1 levels in cerebrospinal fluid after REM sleep deprivation.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2805%2970196-4

7 January 2021

Increased hypocretin-1 (orexin-a) levels in cerebrospinal fluid of rats after short-term forced activity.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2805%2970196-4

7 January 2021

Behavioral correlates of activity in identified hypocretin/orexin neurons

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2805%2970196-4

7 January 2021

Hypocretins (orexins): clinical impact of the discovery of a neurotransmitter

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2805%2970196-4

7 January 2021

Narcolepsy in orexin knockout mice: molecular genetics of sleep regulation

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2805%2970196-4

7 January 2021

Genetic ablation of orexin neurons in mice results in narcolepsy, hypophagia, and obesity.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2805%2970196-4

7 January 2021

Distinct narcolepsy syndromes in Orexin receptor-2 and Orexin null mice: molecular genetic dissection of Non-REM and REM sleep regulatory processes

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2805%2970196-4

7 January 2021

Expression of a poly-glutamine-ataxin-3 transgene in orexin neurons induces narcolepsy-cataplexy in the rat.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2805%2970196-4

7 January 2021

Effects of lateral hypothalamic lesion with the neurotoxin hypocretin-2-saporin on sleep in Long-Evans rats.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2805%2970196-4

7 January 2021

Genetic linkage of autosomal recessive canine narcolepsy with a mu immunoglobulin heavy-chain switch-like segment

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2805%2970196-4

7 January 2021

The sleep disorder canine narcolepsy is caused by a mutation in the hypocretin (orexin) receptor 2 gene

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2805%2970196-4

7 January 2021

Hypocretin levels in sporadic and familial cases of canine narcolepsy

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2805%2970196-4

7 January 2021

Polymorphisms in hypocretin/orexin pathway genes and narcolepsy

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2805%2970196-4

7 January 2021

A mutation in a case of early onset narcolepsy and a generalized absence of hypocretin peptides in human narcoleptic brains

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2805%2970196-4

7 January 2021

A narcolepsy susceptibility locus maps to a 5 Mb region of chromosome 21q.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2805%2970196-4

7 January 2021

Polymorphisms in the vicinity of the hypocretin/orexin are not associated with human narcolepsy

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2805%2970196-4

7 January 2021

The role of cerebrospinal fluid hypocretin measurement in the diagnosis of narcolepsy and other hypersomnias

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2805%2970196-4

7 January 2021

CSF hypocretin-1 levels in narcolepsy, Kleine-Levin syndrome, and other hypersomnias and neurological conditions

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2805%2970196-4

7 January 2021

Hypocretin (orexin) levels in cerebrospinal fluid of patients with narcolepsy: relationship to cataplexy and HLA DQB1*0602 status.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2805%2970196-4

7 January 2021

CSF hypocretin-1 (orexin-A) concentrations in narcolepsy with and without cataplexy and idiopathic hypersomnia.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2805%2970196-4

7 January 2021

In vivo evidence of neuronal loss in the hypothalamus of narcoleptic patients

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2805%2970196-4

7 January 2021

Clinical efficacy of high-dose intravenous immunoglobulins near the onset of narcolepsy in a 10-year-old boy.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2805%2970196-4

7 January 2021

Successful management of cataplexy with intravenous immunoglobulins at narcolepsy onset

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2805%2970196-4

7 January 2021

Screening for anti-ganglioside antibodies in hypocretin-deficient human narcolepsy

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2805%2970196-4

7 January 2021

Search for neuron-specific and nonneuron-specific antibodies in narcoleptic patients with and without HLA DQB1*0602.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2805%2970196-4

7 January 2021

Studies of humoral immunity to preprohypocretin in human leukocyte antigen DQB1*0602-positive narcoleptic subjects with cataplexy.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2805%2970196-4

7 January 2021

A functional autoantibody in narcolepsy.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2805%2970196-4

7 January 2021

Hypocretin (orexin) deficiency in narcolepsy and primary hypersomnia.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2805%2970196-4

7 January 2021

Differential kinetics of hypocretins in the cerebrospinal fluid after intracerebroventricular administration in rats.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2805%2970196-4

7 January 2021

Article reviewed: Plasma orexin-A is lower in patients with narcolepsy.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2805%2970196-4

7 January 2021

The clinical spectrum of narcolepsy with cataplexy: a reappraisal.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2805%2970196-4

7 January 2021

Decreased cerebrospinal fluid hypocretin-1 levels near the onset of narcolepsy in 2 prepubertal children.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2805%2970196-4

7 January 2021

Report of a case of immunosuppression with prednisone in an 8-year-old boy with an acute onset of hypocretin-deficiency narcolepsy

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2805%2970196-4

7 January 2021

Low cerebrospinal fluid hypocretin (Orexin) and altered energy homeostasis in human narcolepsy.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2805%2970196-4

7 January 2021

Hypocretin deficiency in narcoleptic humans is associated with abdominal obesity

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2805%2970196-4

7 January 2021

Low cerebrospinal fluid hypocretin (orexin) and altered energy homeostasis in human narcolepsy

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2805%2970196-4

7 January 2021

Reduction of plasma leptin levels and loss of its circadian rhythmicity in hypocretin (orexin)-deficient narcoleptic humans.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2805%2970196-4

7 January 2021

Orexin peptides prevent cataplexy and improve wakefulness in an orexin neuron-ablated model of narcolepsy in mice

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2805%2970196-4

7 January 2021

Effects of IV and ICV hypocretin-1 (orexin A) in hypocretin receptor-2 gene mutated narcoleptic dogs and IV hypocretin-1 replacement therapy in a hypocretin-ligand-deficient narcoleptic dog.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2805%2970196-4

7 January 2021

Drugs to interfere with orexins (hypocretins).

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2805%2970196-4

7 January 2021

Modafinil more effectively induces wakefulness in orexin-null mice than in wild-type littermates

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2805%2970196-4

7 January 2021

Transplantation of hypocretin neurons into the pontine reticular formation: preliminary results

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2805%2970196-4

7 January 2021

The narcoleptic borderland: a multimodal diagnostic approach including cerebrospinal fluid levels of hypocretin-1 (orexin A).

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2805%2970196-4

7 January 2021

Acquired narcolepsy in an acromegalic patient who underwent pituitary irradiation

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2805%2970196-4

7 January 2021

Narcolepsy caused by acute disseminated encephalomyelitis

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2805%2970196-4

7 January 2021

Monozygotic twins concordant for narcolepsy-cataplexy without any detectable abnormality in the hypocretin (orexin) pathway

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2805%2970196-4

7 January 2021

CSF hypocretin-1 levels in restless legs syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2805%2970196-4

7 January 2021

CSF hypocretin measures in patients with obstructive sleep apnea.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2805%2970196-4

7 January 2021

Narcolepsy and low CSF orexin (hypocretin) concentration after a diencephalic stroke.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2805%2970196-4

7 January 2021

A hypersomnolent girl with decreased CSF hypocretin level after removal of a hypothalamic tumor

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2805%2970196-4

7 January 2021

A case of acute disseminated encephalomyelitis presenting hypersomnia with decreased hypocretin level in cerebrospinal fluid

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2805%2970196-4

7 January 2021

Hypersomnia and low CSF hypocretin-1 (orexin-A) concentration in a patient with multiple sclerosis showing bilateral hypothalamic lesions.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2805%2970196-4

7 January 2021

Hypersomnia, asterixis and cataplexy in association with orexin A-reduced hypothalamic tumor

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2805%2970196-4

7 January 2021

Hypersomnia and low cerebrospinal fluid hypocretin levels in acute disseminated encephalomyelitis.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2805%2970196-4

7 January 2021

Low CSF hypocretin-1/orexin-A associated with hypersomnia secondary to hypothalamic lesion in a case of multiple sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2805%2970196-4

7 January 2021

Hypocretin deficiency in Prader-Willi syndrome.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2805%2970196-4

7 January 2021

Sleep disturbances and hypocretin deficiency in Niemann-Pick disease type C.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2805%2970196-4

7 January 2021

Hypocretin Deficiency in Niemann-Pick Type C with Cataplexy

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2805%2970196-4

7 January 2021

CSF hypocretin/orexin levels in narcolepsy and other neurological conditions.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2805%2970196-4

7 January 2021

Hypocretin-1 (orexin A) deficiency in acute traumatic brain injury.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2805%2970196-4

7 January 2021

Hallucinations, REM sleep, and Parkinson's disease: a medical hypothesis.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2805%2970196-4

7 January 2021

Parkinsonism with excessive daytime sleepiness--a narcolepsy-like disorder?

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2805%2970196-4

7 January 2021

Low levels of ventricular CSF orexin/hypocretin in advanced PD.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2805%2970196-4

7 January 2021

Normal hypocretin-1 levels in Parkinson's disease patients with excessive daytime sleepiness

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2805%2970196-4

7 January 2021

Normal CSF hypocretin-1 (orexin A) levels in dementia with Lewy bodies associated with excessive daytime sleepiness.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2805%2970196-4

7 January 2021

CSF hypocretin levels in Guillain–Barré syndrome and other inflammatory neuropathies

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2805%2970196-4

7 January 2021

Hypocretin-1 (orexin-A) concentrations in cerebrospinal fluid are low in patients with Guillain-Barré syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2805%2970196-4

7 January 2021

CSF hypocretin levels in Guillain-Barré syndrome and other inflammatory neuropathies

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2805%2970196-4

7 January 2021

Vivid dreams, hallucinations, psychosis and REM sleep in Guillain-Barré syndrome.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2805%2970196-4

7 January 2021

Rasmussen's syndrome and new-onset narcolepsy, cataplexy, and epilepsy in an adult.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2805%2970196-4

7 January 2021

Undetectable CSF hypocretin-1 in "Hashimoto's encephalopathy" associated with coma

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2805%2970196-4

7 January 2021

Hypocretin-1 CSF levels in anti-Ma2 associated encephalitis

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2805%2970196-4

7 January 2021

Decreased Hypocretin-1 (Orexin-A) Levels in the Cerebrospinal Fluid of Patients with Myotonic Dystrophy and Excessive Daytime Sleepiness

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2805%2970196-4

7 January 2021

Decreased CSF hypocretin-1 (orexin-A) after acute haemorrhagic brain injury

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2805%2970196-4

7 January 2021

Transient total sleep loss in cerebral Whipple's disease: a longitudinal study

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2805%2970196-4

7 January 2021

Diurnal variation of cerebrospinal fluid hypocretin-1 (Orexin-A) levels in control and depressed subjects

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2805%2970196-4

7 January 2021

Lower CSF orexin A (hypocretin-1) levels in patients with schizophrenia treated with haloperidol compared to unmedicated subjects

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2805%2970196-4

7 January 2021

10.1016/S1474-4422(05)70196-4

Identifiers

DOI

1 reference

13 August 2017

1 reference