(Q36264167)

13 August 2017

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title

Antiviral RNAi therapy: emerging approaches for hitting a moving target (English)

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13 August 2017

Leonard JN

1

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13 August 2017

Schaffer DV

series ordinal

2

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13 August 2017

publication date

1 March 2006

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13 August 2017

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13 August 2017

volume

13

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13 August 2017

issue

6

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13 August 2017

page(s)

532-540

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13 August 2017

cites work

Small RNAs and immunity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302645

Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302645

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302645

21 January 2018

RNA interference--2001.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302645

Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302645

Induction and suppression of RNA silencing by an animal virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302645

A cellular microRNA mediates antiviral defense in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302645

The influenza A virus NS1 protein binds small interfering RNAs and suppresses RNA silencing in plants

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302645

Evidence that HIV-1 encodes an siRNA and a suppressor of RNA silencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302645

Plant viral suppressors of RNA silencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302645

Interferon antagonist proteins of influenza and vaccinia viruses are suppressors of RNA silencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302645

RNA interference in adult mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302645

Inhibition of influenza virus production in virus-infected mice by RNA interference

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302645

Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302645

Inhibition of HIV-1 by lentiviral vector-transduced siRNAs in T lymphocytes differentiated in SCID-hu mice and CD34+ progenitor cell-derived macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302645

RNA interference of influenza virus production by directly targeting mRNA for degradation and indirectly inhibiting all viral RNA transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302645

Protection against lethal influenza virus challenge by RNA interference in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302645

Inhibition of SARS-associated coronavirus infection and replication by RNA interference.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302645

Small interfering RNA Inhibits Hepatitis B virus replication in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302645

Inhibition of hepatitis B virus in mice by RNA interference

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302645

RNA interference-mediated control of hepatitis B virus and emergence of resistant mutant.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302645

Paradigms for conditional expression of RNA interference molecules for use against viral targets.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302645

Modulation of HIV-1 replication by RNA interference

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302645

Cloned zebrafish by nuclear transfer from long-term-cultured cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302645

Human immunodeficiency virus type 1 escape from RNA interference

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302645

Inhibition of HIV-1 infection by lentiviral vectors expressing Pol III-promoted anti-HIV RNAs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302645

Human immunodeficiency virus type 1 escapes from RNA interference-mediated inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302645

Negative feedback inhibition of HIV-1 by TAT-inducible expression of siRNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302645

HIV-1 can escape from RNA interference by evolving an alternative structure in its RNA genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302645

Inhibiting the Arp2/3 complex limits infection of both intracellular mature vaccinia virus and primate lentiviruses

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302645

Sam68 is absolutely required for Rev function and HIV-1 production

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302645

Inhibition of respiratory viruses by nasally administered siRNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302645

Lentiviral-mediated RNA interference

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302645

Gene therapy: twenty-first century medicine

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302645

Expression profiling reveals off-target gene regulation by RNAi

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302645

Short interfering RNAs can induce unexpected and divergent changes in the levels of untargeted proteins in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302645

Overexpression of exportin 5 enhances RNA interference mediated by short hairpin RNAs and microRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302645

ATP requirements and small interfering RNA structure in the RNA interference pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302645

siRNA-mediated gene silencing in vitro and in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302645

Inhibition of the Epstein-Barr virus lytic cycle by Zta-targeted RNA interference

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302645

RNA interference targeting VP1 inhibits foot-and-mouth disease virus replication in BHK-21 cells and suckling mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302645

Inhibition of foot-and-mouth disease virus replication by small interfering RNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302645

Interference of hepatitis C virus RNA replication by short interfering RNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302645

Alternative approaches for efficient inhibition of hepatitis C virus RNA replication by small interfering RNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302645

Hepatitis C Virus Replicons Escape RNA Interference Induced by a Short Interfering RNA Directed against the NS5b Coding Region

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302645

RNA interference of human papillomavirus type 18 E6 and E7 induces senescence in HeLa cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302645

siRNA targeting of the viral E6 oncogene efficiently kills human papillomavirus-positive cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302645

The utility of siRNA transcripts produced by RNA polymerase i in down regulating viral gene expression and replication of negative- and positive-strand RNA viruses

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302645

Inhibition of Marburg virus protein expression and viral release by RNA interference

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302645

Control of nonsegmented negative-strand RNA virus replication by siRNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302645

Short interfering RNA confers intracellular antiviral immunity in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302645

Poliovirus escape from RNA interference: short interfering RNA-target recognition and implications for therapeutic approaches

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302645

Rotavirus gene silencing by small interfering RNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302645

RNA silencing of rotavirus gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302645

Phenotypic silencing of cytoplasmic genes using sequence-specific double-stranded short interfering RNA and its application in the reverse genetics of wild type negative-strand RNA viruses

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302645

siRNA targeting the leader sequence of SARS-CoV inhibits virus replication.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302645

Small interfering RNA inhibits SARS-CoV nucleocapsid gene expression in cultured cells and mouse muscles

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302645

Asymmetry in the assembly of the RNAi enzyme complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302645

Enhanced gene silencing by the application of multiple specific small interfering RNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302645

Bispecific short hairpin siRNA constructs targeted to CD4, CXCR4, and CCR5 confer HIV-1 resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302645

Homozygous defect in HIV-1 coreceptor accounts for resistance of some multiply-exposed individuals to HIV-1 infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302645

RNA interference directed against Poly(ADP-Ribose) polymerase 1 efficiently suppresses human immunodeficiency virus type 1 replication in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302645

Inhibition of human immunodeficiency virus type 1 replication by RNA interference directed against human transcription elongation factor P-TEFb (CDK9/CyclinT1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302645

The cellular HIV-1 Rev cofactor hRIP is required for viral replication.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302645

Enhanced activation of tax-dependent transcription of human T-cell leukemia virus type I (HTLV-I) long terminal repeat by TORC3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302645

Down-regulation of viral replication by adenoviral-mediated expression of siRNA against cellular cofactors for hepatitis C virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302645

Inhibition of Virus Replication by RNA Interference

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302645

Drug-resistance genotyping in HIV-1 therapy: the VIRADAPT randomised controlled trial.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302645

Computational design of antiviral RNA interference strategies that resist human immunodeficiency virus escape.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302645

Stochastic gene expression in a lentiviral positive-feedback loop: HIV-1 Tat fluctuations drive phenotypic diversity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302645

Toward antiviral strategies that resist viral escape

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302645

Geno2pheno: Estimating phenotypic drug resistance from HIV-1 genotypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302645

Methods for optimizing antiviral combination therapies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302645

The causes and consequences of HIV evolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302645

Antiretroviral therapy in HIV patients: aspects of metabolic complications and mitochondrial toxicity.

21 January 2018

1 reference

12 December 2020

Suppression of chemokine receptor expression by RNA interference allows for inhibition of HIV-1 replication

1 reference

12 December 2020

Prophylactic and therapeutic effects of small interfering RNA targeting SARS-coronavirus

1 reference

12 December 2020

Sequence-dependent stimulation of the mammalian innate immune response by synthetic siRNA

1 reference

12 December 2020

1 reference

12 December 2020

siRNA-directed inhibition of HIV-1 infection

1 reference

12 December 2020

Expression of small interfering RNAs targeted against HIV-1 rev transcripts in human cells

1 reference

12 December 2020

Antibody mediated in vivo delivery of small interfering RNAs via cell-surface receptors

1 reference

12 December 2020

Rates of spontaneous mutation

1 reference

12 December 2020

Identifiers

DOI

10.1038/SJ.GT.3302645

1 reference

13 August 2017

1 reference