(Q36268329)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16185156%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

review article

1 reference

title

Targeting the Fas/Fas ligand pathway in cancer (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16185156%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16185156%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

Fergus Shanahan

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16185156%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

author name string

Darren I O'Brien

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16185156%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

Raymond G Kelly

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16185156%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

Terrence M O'Connor

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16185156%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

Joe O'Connell

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16185156%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

language of work or name

English

0 references

publication date

1 October 2005

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16185156%20AND%20SRC:MED&resulttype=core&format=json

Expert Opinion on Therapeutic Targets

7 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16185156%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

volume

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16185156%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

page(s)

1031-1044

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16185156%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

issue

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16185156%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1031

Fas(CD95)/FasL interactions required for programmed cell death after T-cell activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1031

Molecular cloning and expression of the Fas ligand, a novel member of the tumor necrosis factor family

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1031

Molecular ordering of the initial signaling events of CD95.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1031

Two CD95 tumor classes with different sensitivities to antitumor drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1031

Two CD95 (APO-1/Fas) signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1031

Actin dependent CD95 internalization is specific for Type I cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1031

Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1031

A bcl-2 transgene expressed in hepatocytes protects mice from fulminant liver destruction but not from rapid death induced by anti-Fas antibody injection

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1031

Bid-deficient mice are resistant to Fas-induced hepatocellular apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1031

The combined functions of proapoptotic Bcl-2 family members bak and bax are essential for normal development of multiple tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1031

An essential role for membrane rafts in the initiation of Fas/CD95-triggered cell death in mouse thymocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1031

The antitumor ether lipid ET-18-OCH(3) induces apoptosis through translocation and capping of Fas/CD95 into membrane rafts in human leukemic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1031

Ligand-independent redistribution of Fas (CD95) into lipid rafts mediates clonotypic T cell death.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1031

The death-inducing signalling complex is recruited to lipid rafts in Fas-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1031

CD95 death-inducing signaling complex formation and internalization occur in lipid rafts of type I and type II cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1031

Recruitment of TNF receptor 1 to lipid rafts is essential for TNFalpha-mediated NF-kappaB activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1031

Cell-autonomous Fas (CD95)/Fas-ligand interaction mediates activation-induced apoptosis in T-cell hybridomas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1031

Autocrine T-cell suicide mediated by APO-1/(Fas/CD95)

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1031

Fas and Fas ligand: lpr and gld mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1031

Improved survival of biolistically transfected mouse islet allografts expressing CTLA4-Ig or soluble Fas ligand.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1031

CD95 ligand (FasL)-induced apoptosis is necessary for corneal allograft survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1031

Fas ligand expression on islets as well as multiple cell lines results in accelerated neutrophilic rejection

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1031

Transgenic expression of CD95 ligand on islet beta cells induces a granulocytic infiltration but does not confer immune privilege upon islet allografts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1031

Fas ligand expression in islets of Langerhans does not confer immune privilege and instead targets them for rapid destruction

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1031

Fas engagement induces the maturation of dendritic cells (DCs), the release of interleukin (IL)-1beta, and the production of interferon gamma in the absence of IL-12 during DC-T cell cognate interaction: a new role for Fas ligand in inflammatory res

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1031

Fas and perforin pathways as major mechanisms of T cell-mediated cytotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1031

Perforin and granzyme B induce apoptosis in FasL-resistant colon carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1031

Perforin and interferon-gamma activities independently control tumor initiation, growth, and metastasis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1031

Perforin-mediated cytotoxicity is critical for surveillance of spontaneous lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1031

Critical role for tumor necrosis factor-related apoptosis-inducing ligand in immune surveillance against tumor development

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1031

Studies of the mechanism of cytolysis by tumour-infiltrating lymphocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1031

Spontaneous development of plasmacytoid tumors in mice with defective Fas-Fas ligand interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1031

A tumor-suppressor function for Fas (CD95) revealed in T cell-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1031

Mad dogs, Englishmen and apoptosis: the role of cell death in UV-induced skin cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1031

Induction of interferon gamma production by natural killer cell stimulatory factor: characterization of the responder cells and synergy with other inducers

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1031

Cellular responses to interferon-gamma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1031

Enhanced in vivo growth and resistance to rejection of tumor cells expressing dominant negative IFN gamma receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1031

IFNgamma and lymphocytes prevent primary tumour development and shape tumour immunogenicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1031

Demonstration of an interferon gamma-dependent tumor surveillance system in immunocompetent mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1031

Cell growth arrest and induction of cyclin-dependent kinase inhibitor p21 WAF1/CIP1 mediated by STAT1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1031

Interferon-gamma modulates a p53-independent apoptotic pathway and apoptosis-related gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1031

The roles of IFN gamma in protection against tumor development and cancer immunoediting

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1031

Expression of APO-1 (CD95), a member of the NGF/TNF receptor superfamily, in normal and neoplastic colon epithelium

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1031

Protection from Fas-mediated apoptosis by a soluble form of the Fas molecule

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1031

Genomic amplification of a decoy receptor for Fas ligand in lung and colon cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1031

The Fas counterattack: Fas-mediated T cell killing by colon cancer cells expressing Fas ligand

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1031

Fas ligand and Fas receptor are coexpressed in normal human esophageal epithelium: a potential mechanism of apoptotic epithelial turnover

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1031

Inhibition of the alloantibody response by CD95 ligand

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1031

FasL is more frequently expressed in liver metastases of colorectal cancer than in matched primary carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1031

Gene transfer of Fas ligand induces tumor regression in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1031

Fas ligand mediates immune privilege and not inflammation in human colon cancer, irrespective of TGF-beta expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1031

Lethal effect of the anti-Fas antibody in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1031

Fas/FasL interaction: a novel immune therapy approach with immobilized biologicals

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1031

Sensitization of cancer cells treated with cytotoxic drugs to fas-mediated cytotoxicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1031

Activation of the CD95 (APO-1/Fas) pathway in drug- and gamma-irradiation-induced apoptosis of brain tumor cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1031

5-Fluorouracil induced Fas upregulation associated with apoptosis in liver metastases of colorectal cancer patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1031

STAT-1-independent upregulation of FADD and procaspase-3 and -8 in cancer cells treated with cytotoxic drugs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1031

The roles of thymidylate synthase and p53 in regulating Fas-mediated apoptosis in response to antimetabolites

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1031

p53 activates the CD95 (APO-1/Fas) gene in response to DNA damage by anticancer drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1031

The CD95/CD95 ligand system is not the major effector in anticancer drug-mediated apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1031

Fas ligand-independent, FADD-mediated activation of the Fas death pathway by anticancer drugs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1031

Cytoskeleton-mediated death receptor and ligand concentration in lipid rafts forms apoptosis-promoting clusters in cancer chemotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1031

In vitro efficacy of Fas ligand gene therapy for the treatment of bladder cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1031

Epigenetic changes in tumor Fas levels determine immune escape and response to therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1031

MAPK/ERK overrides the apoptotic signaling from Fas, TNF, and TRAIL receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1031

Induction of apoptosis and activation of NF-kappaB by CD95 require different signalling thresholds

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1031

The relevance of NF-kappaB for CD95 signaling in tumor cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1031

CD95 ligand induces motility and invasiveness of apoptosis-resistant tumor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1031

Characterization of the non-functional Fas ligand of gld mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1031

Involvement of the CD95 (APO–1/Fas) receptor/ligand system in drug–induced apoptosis in leukemia cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1031

Cytolytic T-cell cytotoxicity is mediated through perforin and Fas lytic pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1031

Inhibitors of histone deacetylases induce tumor-selective apoptosis through activation of the death receptor pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1031