(Q36273566)

English

Conjugates of γ-Carbolines and Phenothiazine as new selective inhibitors of butyrylcholinesterase and blockers of NMDA receptors for Alzheimer Disease

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scholarly article

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Europe PubMed Central

PMC publication ID

13 August 2017

Conjugates of γ-Carbolines and Phenothiazine as new selective inhibitors of butyrylcholinesterase and blockers of NMDA receptors for Alzheimer Disease (English)

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Europe PubMed Central

PMC publication ID

13 August 2017

Alzheimer's disease

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Sofya V. Lushchekina

2

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26281952%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Alexey Aksinenko

8

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26281952%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

George E. Barreto

9

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26281952%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Gjumrakch Aliev

10

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26281952%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

author name string

Galina F Makhaeva

1

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31 May 2020

Natalia P Boltneva

3

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31 May 2020

Vladimir B Sokolov

4

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31 May 2020

Vladimir V Grigoriev

5

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31 May 2020

Olga G Serebryakova

6

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26281952%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Ekaterina A Vikhareva

7

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31 May 2020

Sergey O Bachurin

11

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31 May 2020

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publication date

18 August 2015

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13 August 2017

Scientific Reports

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31 May 2020

5

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26281952%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

13164

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26281952%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

copyright license

Creative Commons Attribution 4.0 International

18 August 2015

1 reference

April 2022 Public Data File from Crossref

copyright status

0 references

https://scigraph.springernature.com/pub.10.1038/srep13164

0 references

Recent development of multifunctional agents as potential drug candidates for the treatment of Alzheimer's disease.

1 reference

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30 September 2017

Cholinesterase inhibition in Alzheimer's disease: is specificity the answer?

1 reference

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30 September 2017

Multi-target design strategies in the context of Alzheimer's disease: acetylcholinesterase inhibition and NMDA receptor antagonism as the driving forces

1 reference

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30 September 2017

Latrepirdine: molecular mechanisms underlying potential therapeutic roles in Alzheimer's and other neurodegenerative diseases

1 reference

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30 September 2017

From the multifactorial nature of Alzheimer`s disease to multitarget therapy: the contribution of the translational approach.

1 reference

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30 September 2017

The multifactorial nature of Alzheimer's disease for developing potential therapeutics.

1 reference

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30 September 2017

Memantine and cholinesterase inhibitors: complementary mechanisms in the treatment of Alzheimer's disease

1 reference

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30 September 2017

Rationally designed multi-targeted agents against neurodegenerative diseases

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30 September 2017

The role of human carboxylesterases in drug metabolism: have we overlooked their importance?

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30 September 2017

Latrepirdine (Dimebon®), a potential Alzheimer therapeutic, regulates autophagy and neuropathology in an Alzheimer mouse model

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30 September 2017

Rationale for combining glutamatergic and cholinergic approaches in the symptomatic treatment of Alzheimer's disease

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30 September 2017

Organophosphorus compound esterase profiles as predictors of therapeutic and toxic effects

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30 September 2017

Combined QSAR studies of inhibitor properties of O-phosphorylated oximes toward serine esterases involved in neurotoxicity, drug metabolism and Alzheimer's disease

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30 September 2017

Cholinesterase inhibitors and memantine for symptomatic treatment of dementia

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30 September 2017

Why do we need multifunctional neuroprotective and neurorestorative drugs for Parkinson's and Alzheimer's diseases as disease modifying agents

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New pharmacological strategies for treatment of Alzheimer's disease: focus on disease modifying drugs

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30 September 2017

Protective role of methylene blue in Alzheimer's disease via mitochondria and cytochrome c oxidase

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30 September 2017

Methylene blue and dimebon inhibit aggregation of TDP-43 in cellular models.

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30 September 2017

Methylene blue and Alzheimer's disease.

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30 September 2017

AutoDock4 and AutoDockTools4: Automated docking with selective receptor flexibility

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30 September 2017

Amyotrophic lateral sclerosis: A 40-year personal perspective

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30 September 2017

Different cholinesterase inhibitor effects on CSF cholinesterases in Alzheimer patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4642525

30 September 2017

Cholinergic system during the progression of Alzheimer's disease: therapeutic implications

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30 September 2017

Rational design of a drug for Alzheimer's disease with cholinesterase inhibitory and neuroprotective activity

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30 September 2017

Kinetics of human serum butyrylcholinesterase inhibition by a novel experimental Alzheimer therapeutic, dihydrobenzodioxepine cymserine

1 reference

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30 September 2017

Human carboxylesterase isozymes: catalytic properties and rational drug design

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30 September 2017

Rationale for combination therapy with galantamine and memantine in Alzheimer's disease

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30 September 2017

Novel cholinesterase inhibitors as future effective drugs for the treatment of Alzheimer's disease

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30 September 2017

Selective butyrylcholinesterase inhibition elevates brain acetylcholine, augments learning and lowers Alzheimer beta-amyloid peptide in rodent

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Targeting acetylcholinesterase and butyrylcholinesterase in dementia

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Cholinesterase inhibitors used in the treatment of Alzheimer's disease: the relationship between pharmacological effects and clinical efficacy

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Crystal structure of human butyrylcholinesterase and of its complexes with substrate and products

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12 December 2020

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10.1038/SREP13164

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26281952%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26281952%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26281952%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

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