(Q36274219)

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A novel neuroferritinopathy mouse model (FTL 498InsTC) shows progressive brain iron dysregulation, morphological signs of early neurodegeneration and motor coordination deficits.

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23 February 2020

A novel neuroferritinopathy mouse model (FTL 498InsTC) shows progressive brain iron dysregulation, morphological signs of early neurodegeneration and motor coordination deficits (English)

1 reference

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23 February 2020

neurodegeneration

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23 February 2020

Letterio S. Politi

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23 February 2020

Francesca Cirulli

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23 February 2020

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23 February 2020

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23 February 2020

author name string

Federica Maccarinelli

1

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23 February 2020

Antonella Pagani

2

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23 February 2020

Anna Cozzi

3

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23 February 2020

Franca Codazzi

4

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23 February 2020

Giuseppina Di Giacomo

5

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23 February 2020

Sara Capoccia

6

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23 February 2020

Stefania Rapino

7

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23 February 2020

Ottavio Cremona

12

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23 February 2020

Fabio Grohovaz

13

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23 February 2020

publication date

4 November 2014

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23 February 2020

Neurobiology of Disease

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23 February 2020

81

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23 February 2020

119-133

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23 February 2020

Neurodegeneration with brain iron accumulation: update on pathogenic mechanisms

1 reference

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30 September 2017

A novel ferritin light chain mutation in neuroferritinopathy with an atypical presentation

1 reference

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30 September 2017

Lipofuscin: formation, effects and role of macroautophagy

1 reference

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30 September 2017

Abnormal iron homeostasis and neurodegeneration

1 reference

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30 September 2017

Iron metabolism in the CNS: implications for neurodegenerative diseases

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30 September 2017

Functional roles of neurotransmitters and neuromodulators in the dorsal striatum.

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30 September 2017

Neurodegeneration with brain iron accumulation

1 reference

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30 September 2017

A mutant light-chain ferritin that causes neurodegeneration has enhanced propensity toward oxidative damage.

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30 September 2017

MRI findings in neuroferritinopathy

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30 September 2017

Iron-related MRI images in patients with pantothenate kinase-associated neurodegeneration (PKAN) treated with deferiprone: results of a phase II pilot trial

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30 September 2017

Susceptibility-weighted imaging of the brain: current utility and potential applications

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30 September 2017

Regulation of the 26S proteasome complex during oxidative stress

1 reference

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30 September 2017

Abnormal iron metabolism in fibroblasts from a patient with the neurodegenerative disease hereditary ferritinopathy

1 reference

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30 September 2017

Bisretinoids of RPE lipofuscin: trigger for complement activation in age-related macular degeneration

1 reference

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30 September 2017

Accumulation of oxidative DNA damage in brain mitochondria in mouse model of hereditary ferritinopathy

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30 September 2017

Cytosolic and mitochondrial ferritins in the regulation of cellular iron homeostasis and oxidative damage

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30 September 2017

Mutant ferritin L-chains that cause neurodegeneration act in a dominant-negative manner to reduce ferritin iron incorporation

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30 September 2017

Oxidative stress and cell death in cells expressing L-ferritin variants causing neuroferritinopathy

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30 September 2017

Abnormal iron metabolism and oxidative stress in mice expressing a mutant form of the ferritin light polypeptide gene

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30 September 2017

Tests to assess motor phenotype in mice: a user's guide

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30 September 2017

Iron-mediated aggregation and a localized structural change characterize ferritin from a mutant light chain polypeptide that causes neurodegeneration.

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30 September 2017

T2* and FSE MRI distinguishes four subtypes of neurodegeneration with brain iron accumulation

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30 September 2017

The comparative biology of neuromelanin and lipofuscin in the human brain

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30 September 2017

Expression of a mutant form of the ferritin light chain gene induces neurodegeneration and iron overload in transgenic mice

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30 September 2017

Mitochondrial ferritin expression in adult mouse tissues

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30 September 2017

Neuroferritinopathy: missense mutation in FTL causing early-onset bilateral pallidal involvement.

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30 September 2017

Lipofuscin: mechanisms of age-related accumulation and influence on cell function

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30 September 2017

Mutation in the gene encoding ferritin light polypeptide causes dominant adult-onset basal ganglia disease

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

Iron handling in hippocampal neurons: activity-dependent iron entry and mitochondria-mediated neurotoxicity.

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22 September 2018

Quantitative assessment of brain iron by R(2)* relaxometry in patients with clinically isolated syndrome and relapsing-remitting multiple sclerosis.

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22 September 2018

A novel ferritin light chain gene mutation in a Japanese family with neuroferritinopathy: description of clinical features and implications for genotype-phenotype correlations.

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22 September 2018

Clinical features and natural history of neuroferritinopathy caused by the 458dupA FTL mutation

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22 September 2018

Hereditary ferritinopathy: a novel mutation, its cellular pathology, and pathogenetic insights.

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22 September 2018

Intracellular ferritin accumulation in neural and extraneural tissue characterizes a neurodegenerative disease associated with a mutation in the ferritin light polypeptide gene

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22 September 2018

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22 September 2018

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22 September 2018

Up and down states in striatal medium spiny neurons simultaneously recorded with spontaneous activity in fast-spiking interneurons studied in cortex-striatum-substantia nigra organotypic cultures.

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22 September 2018

Characterization of the l-ferritin variant 460InsA responsible of a hereditary ferritinopathy disorder

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A vector for expressing foreign genes in the brains and hearts of transgenic mice

1 reference

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12 December 2020

based on heuristic

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Differential impairment of 20S and 26S proteasome activities in human hematopoietic K562 cells during oxidative stress

1 reference

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based on heuristic

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Identifiers

10.1016/J.NBD.2014.10.023

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23 February 2020

1 reference

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23 February 2020

1 reference

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23 February 2020

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