(Q36288742)

English

Beta cell-specific deficiency of the stimulatory G protein alpha-subunit Gsalpha leads to reduced beta cell mass and insulin-deficient diabetes.

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scholarly article

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Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18029451%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

Beta cell-specific deficiency of the stimulatory G protein alpha-subunit Gsalpha leads to reduced beta cell mass and insulin-deficient diabetes (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18029451%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

Lee S. Weinstein

5

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27 December 2019

author name string

Tao Xie

1

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27 December 2019

Min Chen

2

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27 December 2019

Qing-Hong Zhang

3

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27 December 2019

Zheng Ma

4

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27 December 2019

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20 November 2007

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27 December 2019

number of pages

6

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Proceedings of the National Academy of Sciences of the United States of America

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27 December 2019

104

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27 December 2019

49

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27 December 2019

19601-19606

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27 December 2019

describes a project that uses

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11 June 2022

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Intrinsic regulators of pancreatic beta-cell proliferation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2148335

30 September 2017

The alternative stimulatory G protein alpha-subunit XLalphas is a critical regulator of energy and glucose metabolism and sympathetic nerve activity in adult mice

1 reference

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30 September 2017

RIP-Cre revisited, evidence for impairments of pancreatic beta-cell function

1 reference

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30 September 2017

Assessment of human pancreatic islet architecture and composition by laser scanning confocal microscopy

1 reference

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30 September 2017

Glucagon-like peptide-1 protects beta cells from cytokine-induced apoptosis and necrosis: role of protein kinase B.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2148335

30 September 2017

Cyclins D2 and D1 are essential for postnatal pancreatic beta-cell growth

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2148335

30 September 2017

Beta cell replication is the primary mechanism for maintaining postnatal beta cell mass.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2148335

30 September 2017

Minireview: Glucagon-like peptides regulate cell proliferation and apoptosis in the pancreas, gut, and central nervous system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2148335

30 September 2017

Gluco-incretins control insulin secretion at multiple levels as revealed in mice lacking GLP-1 and GIP receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2148335

30 September 2017

Glucagon-like peptide-1 regulates proliferation and apoptosis via activation of protein kinase B in pancreatic INS-1 beta cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2148335

30 September 2017

Of mice and MEN1: Insulinomas in a conditional mouse knockout

1 reference

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30 September 2017

cAMP promotes pancreatic beta-cell survival via CREB-mediated induction of IRS2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2148335

30 September 2017

Glucagon-like peptide 1 induces pancreatic beta-cell proliferation via transactivation of the epidermal growth factor receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2148335

30 September 2017

Beta-cell deficit and increased beta-cell apoptosis in humans with type 2 diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2148335

30 September 2017

Regulation of insulin action and pancreatic beta-cell function by mutated alleles of the gene encoding forkhead transcription factor Foxo1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2148335

30 September 2017

Endocrine manifestations of stimulatory G protein alpha-subunit mutations and the role of genomic imprinting

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2148335

30 September 2017

Cell cycle control of pancreatic beta cell proliferation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2148335

30 September 2017

Loss of Cdk4 expression causes insulin-deficient diabetes and Cdk4 activation results in beta-islet cell hyperplasia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2148335

30 September 2017

Dual roles for glucokinase in glucose homeostasis as determined by liver and pancreatic beta cell-specific gene knock-outs using Cre recombinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2148335

30 September 2017

Increased glucose tolerance and reduced adiposity in the absence of fasting hypoglycemia in mice with liver-specific Gs alpha deficiency

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2148335

29 June 2018

Effects of insulin and sulphonylureas on insulin-like growth factor-I levels in streptozotocin-induced diabetic rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2148335

29 June 2018

Glibenclamide stimulates growth of human chondrocytes by IGF I dependent mechanisms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2148335

29 June 2018

Low serum somatomedin-C in insulin-dependent diabetes: evidence for a postreceptor mechanism.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2148335

29 June 2018

Receptor and effector interactions of Gs. Functional studies with antibodies to the alpha s carboxyl-terminal decapeptide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2148335

29 June 2018

Downregulation of EGF receptor signaling in pancreatic islets causes diabetes due to impaired postnatal beta-cell growth.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2148335

22 September 2018

Beta-cell growth: an unusual paradigm of organogenesis that is cyclin D2/Cdk4 dependent.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2148335

22 September 2018

Regulation of cyclin D2 and the cyclin D2 promoter by protein kinase A and CREB in lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2148335

22 September 2018

beta-Cell Pdx1 expression is essential for the glucoregulatory, proliferative, and cytoprotective actions of glucagon-like peptide-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2148335

22 September 2018

Characterization of the abnormal pancreatic development, reduced growth and infertility in Cdk4 mutant mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2148335

22 September 2018

Analysis of the Cre-mediated recombination driven by rat insulin promoter in embryonic and adult mouse pancreas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2148335

22 September 2018

Effect of insulin on the hepatic production of insulin-like growth factor-binding protein-1 (IGFBP-1), IGFBP-3, and IGF-I in insulin-dependent diabetes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2148335

22 September 2018

Growth restoration of insulin-deficient diabetic rats by recombinant human insulin-like growth factor I

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0704796104

21 January 2018

Low Plasma Somatomedin-C in Streptozotocin-induced Diabetes Mellitus: Correlation with Changes in Somatogenic and Lactogenic Liver Binding Sites

1 reference

https://pubmed.ncbi.nlm.nih.gov/18029451

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chondrocyte-specific knockout of the G protein G(s)alpha leads to epiphyseal and growth plate abnormalities and ectopic chondrocyte formation

1 reference

https://pubmed.ncbi.nlm.nih.gov/18029451

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Total insulin and IGF-I resistance in pancreatic beta cells causes overt diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/18029451

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transcriptional regulation of cyclin D2 by the PKA pathway and inducible cAMP early repressor in granulosa cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/18029451

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Does IGF-I stimulate pancreatic islet cell growth?

1 reference

https://pubmed.ncbi.nlm.nih.gov/18029451

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1073/PNAS.0704796104

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18029451%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

2007PNAS..10419601X

0 references

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18029451%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18029451%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

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