(Q36289101)

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G proteins in development

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scholarly article

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Europe PubMed Central

13 August 2017

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Europe PubMed Central

G proteins in development (English)

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Europe PubMed Central

13 August 2017

author name string

Craig C Malbon

1

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Europe PubMed Central

13 August 2017

publication date

1 September 2005

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Europe PubMed Central

13 August 2017

Nature Reviews Molecular Cell Biology

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Europe PubMed Central

13 August 2017

6

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Europe PubMed Central

13 August 2017

9

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Europe PubMed Central

13 August 2017

689-701

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Europe PubMed Central

13 August 2017

https://scigraph.springernature.com/pub.10.1038/nrm1716

0 references

Trimeric G protein-dependent frizzled signaling in Drosophila

1 reference

https://api.crossref.org/works/10.1038%2FNRM1716

21 January 2018

Mechanisms of protein prenylation and role in G protein function

1 reference

https://api.crossref.org/works/10.1038%2FNRM1716

21 January 2018

Signal transduction. MAP kinase signaling specificity

1 reference

https://api.crossref.org/works/10.1038%2FNRM1716

21 January 2018

A DNA damage and stress inducible G protein-coupled receptor blocks cells in G2/M

1 reference

https://api.crossref.org/works/10.1038%2FNRM1716

21 January 2018

Two G protein oncogenes in human endocrine tumors

1 reference

https://api.crossref.org/works/10.1038%2FNRM1716

21 January 2018

Inborn errors of signal transduction: mutations in G proteins and G protein-coupled receptors as a cause of disease

1 reference

https://api.crossref.org/works/10.1038%2FNRM1716

21 January 2018

Heterotrimeric G-proteins and development

1 reference

https://api.crossref.org/works/10.1038%2FNRM1716

21 January 2018

Extended life-span and stress resistance in the Drosophila mutant methuselah

1 reference

https://api.crossref.org/works/10.1038%2FNRM1716

21 January 2018

The Drosophila gastrulation gene concertina encodes a G alpha-like protein

1 reference

https://api.crossref.org/works/10.1038%2FNRM1716

21 January 2018

Antisense oligodeoxynucleotides to GS protein alpha-subunit sequence accelerate differentiation of fibroblasts to adipocytes

1 reference

https://api.crossref.org/works/10.1038%2FNRM1716

21 January 2018

Induction of G alpha i2-specific antisense RNA in vivo inhibits neonatal growth

1 reference

https://api.crossref.org/works/10.1038%2FNRM1716

21 January 2018

Paternal versus maternal transmission of a stimulatory G-protein alpha subunit knockout produces opposite effects on energy metabolism

1 reference

https://api.crossref.org/works/10.1038%2FNRM1716

21 January 2018

Mouse models to study G-protein-mediated signaling

1 reference

https://api.crossref.org/works/10.1038%2FNRM1716

21 January 2018

G protein defects in signal transduction

1 reference

https://api.crossref.org/works/10.1038%2FNRM1716

21 January 2018

G protein signaling from activated rat frizzled-1 to the beta-catenin-Lef-Tcf pathway.

1 reference

https://api.crossref.org/works/10.1038%2FNRM1716

21 January 2018

Interaction of Wnt and a Frizzled homologue triggers G-protein-linked phosphatidylinositol signalling

1 reference

https://api.crossref.org/works/10.1038%2FNRM1716

21 January 2018

Signaling through Gs alpha is required for the growth and function of neuromuscular synapses in Drosophila.

1 reference

https://api.crossref.org/works/10.1038%2FNRM1716

21 January 2018

Severe endocrine and nonendocrine manifestations of the McCune-Albright syndrome associated with activating mutations of stimulatory G protein GS.

1 reference

https://api.crossref.org/works/10.1038%2FNRM1716

21 January 2018

Variable and tissue-specific hormone resistance in heterotrimeric Gs protein alpha-subunit (Gsalpha) knockout mice is due to tissue-specific imprinting of the gsalpha gene

1 reference

https://api.crossref.org/works/10.1038%2FNRM1716

21 January 2018

Integration of signaling networks that regulate Dictyostelium differentiation

1 reference

https://api.crossref.org/works/10.1038%2FNRM1716

21 January 2018

A protein complex containing Inscuteable and the Galpha-binding protein Pins orients asymmetric cell divisions in Drosophila

1 reference

https://api.crossref.org/works/10.1038%2FNRM1716

21 January 2018

Regulatory contribution of heterotrimeric G-proteins to oocyte maturation in the sea urchin.

1 reference

https://api.crossref.org/works/10.1038%2FNRM1716

21 January 2018

Activation of a frizzled-2/beta-adrenergic receptor chimera promotes Wnt signaling and differentiation of mouse F9 teratocarcinoma cells via Galphao and Galphat

1 reference

https://api.crossref.org/works/10.1038%2FNRM1716

21 January 2018

Signaling of rat Frizzled-2 through phosphodiesterase and cyclic GMP

1 reference

https://api.crossref.org/works/10.1038%2FNRM1716

21 January 2018

Ulcerative colitis and adenocarcinoma of the colon in G alpha i2-deficient mice.

1 reference

https://api.crossref.org/works/10.1038%2FNRM1716

21 January 2018

Insulin action impaired by deficiency of the G-protein subunit G ialpha2

1 reference

https://api.crossref.org/works/10.1038%2FNRM1716

21 January 2018

Roles of G protein subunits in transmembrane signalling.

1 reference

https://api.crossref.org/works/10.1038%2FNRM1716

21 January 2018

The heterotrimeric protein Go is required for the formation of heart epithelium in Drosophila

1 reference

https://api.crossref.org/works/10.1038%2FNRM1716

21 January 2018

Serotonin promotes G(o)-dependent neuronal migration in Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1038%2FNRM1716

21 January 2018

Pertussis toxin specifically inhibits growth cone guidance by a mechanism independent of direct G protein inactivation

1 reference

https://api.crossref.org/works/10.1038%2FNRM1716

21 January 2018

G0 is a major growth cone protein subject to regulation by GAP-43.

1 reference

https://api.crossref.org/works/10.1038%2FNRM1716

21 January 2018

Heterotrimeric G‐proteins associate with microtubules during differentiation in PC12 pheochromocytoma cells

1 reference

https://api.crossref.org/works/10.1038%2FNRM1716

21 January 2018

A large family of putative transmembrane receptors homologous to the product of the Drosophila tissue polarity gene frizzled

1 reference

https://api.crossref.org/works/10.1038%2FNRM1716

21 January 2018

Wnt-frizzled signaling to G-protein-coupled effectors

1 reference

https://api.crossref.org/works/10.1038%2FNRM1716

21 January 2018

Multiple neurological abnormalities in mice deficient in the G protein Go

1 reference

https://api.crossref.org/works/10.1038%2FNRM1716

21 January 2018

Isolation of the alpha subunits of GTP-binding regulatory proteins by affinity chromatography with immobilized beta gamma subunits

1 reference

https://api.crossref.org/works/10.1038%2FNRM1716

21 January 2018

Impaired motor coordination and persistent multiple climbing fiber innervation of cerebellar Purkinje cells in mice lacking Galphaq

1 reference

https://api.crossref.org/works/10.1038%2FNRM1716

21 January 2018

Embryonic cardiomyocyte hypoplasia and craniofacial defects in G alpha q/G alpha 11-mutant mice

1 reference

https://api.crossref.org/works/10.1038%2FNRM1716

21 January 2018

Effects of G-protein mutations on skin color

1 reference

https://api.crossref.org/works/10.1038%2FNRM1716

21 January 2018

Modulation of EGF receptor-mediated vulva development by the heterotrimeric G-protein Galphaq and excitable cells in C. elegans

1 reference

https://api.crossref.org/works/10.1038%2FNRM1716

21 January 2018

In vivo functions of heterotrimeric G-proteins: studies in Galpha-deficient mice.

1 reference

https://api.crossref.org/works/10.1038%2FNRM1716

21 January 2018

Embryonic handedness choice in C. elegans involves the Galpha protein GPA-16.

1 reference

https://api.crossref.org/works/10.1038%2FNRM1716

21 January 2018

PDE6 is an effector for the Wnt/Ca2+/cGMP-signalling pathway in development

1 reference

https://api.crossref.org/works/10.1038%2FNRM1716

21 January 2018

G(z alpha) deficient mice: enzyme levels in the autonomic nervous system, neuronal survival and effect of genetic background.

1 reference

https://api.crossref.org/works/10.1038%2FNRM1716

21 January 2018

Interaction of G alpha(12) with G alpha(13) and G alpha(q) signaling pathways

1 reference

https://api.crossref.org/works/10.1038%2FNRM1716

21 January 2018

Activation of Gz attenuates Rap1-mediated differentiation of PC12 cells

1 reference

https://api.crossref.org/works/10.1038%2FNRM1716

21 January 2018

Galphaz inhibits serum response factor-dependent transcription by inhibiting Rho signaling

1 reference

https://api.crossref.org/works/10.1038%2FNRM1716

21 January 2018

G alpha 13 signals via p115RhoGEF cascades regulating JNK1 and primitive endoderm formation

1 reference

https://api.crossref.org/works/10.1038%2FNRM1716

21 January 2018

Vascular system defects and impaired cell chemokinesis as a result of Galpha13 deficiency

1 reference

https://api.crossref.org/works/10.1038%2FNRM1716

21 January 2018

Identification and molecular characterization of the G alpha12-Rho guanine nucleotide exchange factor pathway in Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1038%2FNRM1716

21 January 2018

Hyperactivation of the G12-mediated signaling pathway in Caenorhabditis elegans induces a developmental growth arrest via protein kinase C.

1 reference

https://api.crossref.org/works/10.1038%2FNRM1716

21 January 2018

New roles for G-protein beta gamma-dimers in transmembrane signalling.

1 reference

https://api.crossref.org/works/10.1038%2FNRM1716

21 January 2018

G proteins are required for spatial orientation of early cell cleavages in C. elegans embryos.

1 reference

https://api.crossref.org/works/10.1038%2FNRM1716

21 January 2018

Heterotrimeric G proteins direct two modes of asymmetric cell division in the Drosophila nervous system

1 reference

https://api.crossref.org/works/10.1038%2FNRM1716

21 January 2018

Distinct roles of Galphai and Gbeta13F subunits of the heterotrimeric G protein complex in the mediation of Drosophila neuroblast asymmetric divisions

1 reference

https://api.crossref.org/works/10.1038%2FNRM1716

21 January 2018

Heterotrimeric G proteins regulate daughter cell size asymmetry in Drosophila neuroblast divisions.

1 reference

https://api.crossref.org/works/10.1038%2FNRM1716

21 January 2018

Differential functions of G protein and Baz-aPKC signaling pathways in Drosophila neuroblast asymmetric division.

1 reference

https://api.crossref.org/works/10.1038%2FNRM1716

21 January 2018

Distinct roles for Galpha and Gbetagamma in regulating spindle position and orientation in Caenorhabditis elegans embryos.

1 reference

https://api.crossref.org/works/10.1038%2FNRM1716

21 January 2018

Mice with deficiency of G protein gamma3 are lean and have seizures

1 reference

https://api.crossref.org/works/10.1038%2FNRM1716

21 January 2018

Loss of G protein gamma 7 alters behavior and reduces striatal alpha(olf) level and cAMP production

1 reference

https://api.crossref.org/works/10.1038%2FNRM1716

21 January 2018

Transgenic Galphaq overexpression induces cardiac contractile failure in mice

1 reference

https://api.crossref.org/works/10.1038%2FNRM1716

21 January 2018

Wnt signaling and heterotrimeric G-proteins: strange bedfellows or a classic romance?

1 reference

https://api.crossref.org/works/10.1038%2FNRM1716

21 January 2018

Wnt signaling, Ca2+, and cyclic GMP: visualizing Frizzled functions

1 reference

https://api.crossref.org/works/10.1038%2FNRM1716

21 January 2018

Wnt signaling--20 years and counting.

1 reference

https://api.crossref.org/works/10.1038%2FNRM1716

21 January 2018

Longevity determination genes in Drosophila melanogaster

1 reference

https://api.crossref.org/works/10.1038%2FNRM1716

21 January 2018

The Hedgehog response network: sensors, switches, and routers

1 reference

https://api.crossref.org/works/10.1038%2FNRM1716

21 January 2018

The endogenous ligand Stunted of the GPCR Methuselah extends lifespan in Drosophila

1 reference

https://api.crossref.org/works/10.1038%2FNRM1716

21 January 2018

Small molecule modulation of Smoothened activity

1 reference

https://api.crossref.org/works/10.1038%2FNRM1716

21 January 2018

Activity-dependent internalization of smoothened mediated by beta-arrestin 2 and GRK2

1 reference

https://api.crossref.org/works/10.1038%2FNRM1716

21 January 2018

Nerve growth cone guidance mediated by G protein-coupled receptors.

1 reference

https://api.crossref.org/works/10.1038%2FNRM1716

21 January 2018

G protein-coupled receptor-dependent development of human frontal cortex

1 reference

https://api.crossref.org/works/10.1038%2FNRM1716

21 January 2018

Galphaq and Galpha11 proteins mediate endothelin-1 signaling in neural crest-derived pharyngeal arch mesenchyme.

1 reference

https://api.crossref.org/works/10.1038%2FNRM1716

21 January 2018

TheC. elegansG-protein-coupled receptor SRA-13 inhibits RAS/MAPK signalling during olfaction and vulval development

1 reference

https://api.crossref.org/works/10.1038%2FNRM1716

21 January 2018

Frizzleds: new members of the superfamily of G-protein-coupled receptors

1 reference

https://api.crossref.org/works/10.1038%2FNRM1716

21 January 2018

Cellular regulation of RGS proteins: modulators and integrators of G protein signaling

1 reference

https://api.crossref.org/works/10.1038%2FNRM1716

21 January 2018

Morpholino-based gene knockdown screen of novel genes with developmental function in Ciona intestinalis

1 reference

https://api.crossref.org/works/10.1038%2FNRM1716

21 January 2018

A regulator of G protein signaling-containing kinase is important for chemotaxis and multicellular development in dictyostelium

1 reference

https://api.crossref.org/works/10.1038%2FNRM1716

21 January 2018

Accessory proteins for G protein-signaling systems: activators of G protein signaling and other nonreceptor proteins influencing the activation state of G proteins

1 reference

https://api.crossref.org/works/10.1038%2FNRM1716

21 January 2018

Analysis of partner of inscuteable, a novel player of Drosophila asymmetric divisions, reveals two distinct steps in inscuteable apical localization

1 reference

https://api.crossref.org/works/10.1038%2FNRM1716

21 January 2018

Asymmetrically distributed C. elegans homologs of AGS3/PINS control spindle position in the early embryo

1 reference

https://api.crossref.org/works/10.1038%2FNRM1716

21 January 2018

Mammalian Pins is a conformational switch that links NuMA to heterotrimeric G proteins

1 reference

https://api.crossref.org/works/10.1038%2FNRM1716

21 January 2018

AKAP signalling complexes: focal points in space and time

1 reference

https://api.crossref.org/works/10.1038%2FNRM1716

21 January 2018

AKAPs (A-kinase anchoring proteins) and molecules that compose their G-protein-coupled receptor signalling complexes

1 reference

https://api.crossref.org/works/10.1038%2FNRM1716

21 January 2018

Protein kinase A regulates AKAP250 (gravin) scaffold binding to the beta2-adrenergic receptor

1 reference

https://api.crossref.org/works/10.1038%2FNRM1716

21 January 2018

AKAP (A-kinase anchoring protein) domains: beads of structure-function on the necklace of G-protein signalling

1 reference

https://api.crossref.org/works/10.1038%2FNRM1716

21 January 2018

The Frizzled-1/(beta(2))-adrenergic receptor chimera: pharmacological properties of a unique G protein-linked receptor

1 reference

https://api.crossref.org/works/10.1038%2FNRM1716

21 January 2018

Galpha-mediated inhibition of developmental signal response.

1 reference

https://api.crossref.org/works/10.1038%2FNRM1716

21 January 2018

Control of embryonic spindle positioning and Galpha activity by C. elegans RIC-8.

1 reference

https://api.crossref.org/works/10.1038%2FNRM1716

21 January 2018

RGS-7 completes a receptor-independent heterotrimeric G protein cycle to asymmetrically regulate mitotic spindle positioning in C. elegans

1 reference

https://api.crossref.org/works/10.1038%2FNRM1716

21 January 2018

RGS14 is a mitotic spindle protein essential from the first division of the mammalian zygote

1 reference

https://api.crossref.org/works/10.1038%2FNRM1716

21 January 2018

RIC-8 is required for GPR-1/2-dependent Galpha function during asymmetric division of C. elegans embryos

1 reference

https://api.crossref.org/works/10.1038%2FNRM1716

21 January 2018

Meiotic arrest in the mouse follicle maintained by a Gs protein in the oocyte

1 reference

https://api.crossref.org/works/10.1038%2FNRM1716

21 January 2018

A mutant alpha subunit of Gi2 induces neoplastic transformation of Rat-1 cells

1 reference

https://api.crossref.org/works/10.1038%2FNRM1716

21 January 2018

Ca(2+)/calmodulin-dependent protein kinase II is stimulated by Wnt and Frizzled homologs and promotes ventral cell fates in Xenopus

1 reference

https://api.crossref.org/works/10.1038%2FNRM1716

21 January 2018

Physiological regulation of G protein-linked signaling

1 reference

https://api.crossref.org/works/10.1038%2FNRM1716

31 March 2020

cAMP receptor and G-protein interactions control development in Dictyostelium

1 reference

https://api.crossref.org/works/10.1038%2FNRM1716

31 March 2020

Constitutively active mutant GS alpha (G225T) and null-mutant G alpha i-2 (G203T) induce primitive endoderm from stem cells

1 reference

https://api.crossref.org/works/10.1038%2FNRM1716

31 March 2020

Regulation of the differentiation of teratocarcinoma cells into primitive endoderm by G alpha i2

1 reference

https://api.crossref.org/works/10.1038%2FNRM1716

31 March 2020

Induction of Galphaq-specific antisense RNA in vivo causes increased body mass and hyperadiposity

1 reference

https://api.crossref.org/works/10.1038%2FNRM1716

31 March 2020

Altered levels of Gq activity modulate axonal pathfinding in Drosophila.

1 reference

https://api.crossref.org/works/10.1038%2FNRM1716

31 March 2020

c-Jun amino-terminal kinase is regulated by Galpha12/Galpha13 and obligate for differentiation of P19 embryonal carcinoma cells by retinoic acid

1 reference

https://api.crossref.org/works/10.1038%2FNRM1716

31 March 2020

The G12 family of heterotrimeric G proteins and Rho GTPase mediate Sonic hedgehog signalling

1 reference

https://api.crossref.org/works/10.1038%2FNRM1716

31 March 2020

Dynamic expression of RGS4 in the developing nervous system and regulation by the neural type-specific transcription factor Phox2b.

1 reference

https://api.crossref.org/works/10.1038%2FNRM1716

31 March 2020

Activation of rat frizzled-1 promotes Wnt signaling and differentiation of mouse F9 teratocarcinoma cells via pathways that require Galpha(q) and Galpha(o) function

1 reference

https://api.crossref.org/works/10.1038%2FNRM1716

31 March 2020

Conditional, tissue-specific expression of Q205L G alpha i2 in vivo mimics insulin action

1 reference

https://api.crossref.org/works/10.1038%2FNRM1716

31 March 2020

MEKK4 mediates differentiation in response to retinoic acid via activation of c-Jun N-terminal kinase in rat embryonal carcinoma P19 cells

1 reference

https://api.crossref.org/works/10.1038%2FNRM1716

31 March 2020

Galpha12 and Galpha13 mediate differentiation of P19 mouse embryonal carcinoma cells in response to retinoic acid

1 reference

https://api.crossref.org/works/10.1038%2FNRM1716

7 January 2021

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10.1038/NRM1716

1 reference

Europe PubMed Central

13 August 2017

1 reference

Europe PubMed Central

13 August 2017

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