(Q36294710)

13 August 2017

1 reference

title

Emerging functions of mammalian mitochondrial fusion and fission (English)

1 reference

13 August 2017

Hsiuchen Chen

1

1 reference

PubMed ID

16244327

13 August 2017

David C Chan

series ordinal

2

1 reference

13 August 2017

1 October 2005

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13 August 2017

Human Molecular Genetics

1 reference

13 August 2017

14 Spec No. 2

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13 August 2017

R283-9

1 reference

Disruption of fusion results in mitochondrial heterogeneity and dysfunction

13 August 2017

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI270

Mitofusins Mfn1 and Mfn2 coordinately regulate mitochondrial fusion and are essential for embryonic development

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI270

Loss of the intermembrane space protein Mgm1/OPA1 induces swelling and localized constrictions along the lengths of mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI270

Loss of OPA1 perturbates the mitochondrial inner membrane structure and integrity, leading to cytochrome c release and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI270

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI270

The mitochondrial protein hFis1 regulates mitochondrial fission in mammalian cells through an interaction with the dynamin-like protein DLP1

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI270

Levels of human Fis1 at the mitochondrial outer membrane regulate mitochondrial morphology

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI270

OPA1 requires mitofusin 1 to promote mitochondrial fusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI270

Two Mitofusin Proteins, Mammalian Homologues of FZO, with Distinct Functions Are Both Required for Mitochondrial Fusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI270

Regulation of mitochondrial morphology by membrane potential, and DRP1-dependent division and FZO1-dependent fusion reaction in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI270

Mitochondrial fusion in human cells is efficient, requires the inner membrane potential, and is mediated by mitofusins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI270

Mitofusin-1 protein is a generally expressed mediator of mitochondrial fusion in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI270

The human dynamin-related protein OPA1 is anchored to the mitochondrial inner membrane facing the inter-membrane space

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI270

Mutation spectrum and splicing variants in the OPA1 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI270

Differential sublocalization of the dynamin-related protein OPA1 isoforms in mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI270

Processing of Mgm1 by the Rhomboid-type Protease Pcp1 Is Required for Maintenance of Mitochondrial Morphology and of Mitochondrial DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI270

Mitochondrial membrane remodelling regulated by a conserved rhomboid protease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI270

Cells lacking Pcp1p/Ugo2p, a rhomboid-like protease required for Mgm1p processing, lose mtDNA and mitochondrial structure in a Dnm1p-dependent manner, but remain competent for mitochondrial fusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI270

Alternative topogenesis of Mgm1 and mitochondrial morphology depend on ATP and a functional import motor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI270

The intramitochondrial dynamin-related GTPase, Mgm1p, is a component of a protein complex that mediates mitochondrial fusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI270

Intra- and intermolecular domain interactions of the C-terminal GTPase effector domain of the multimeric dynamin-like GTPase Drp1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI270

Roles of the mammalian mitochondrial fission and fusion mediators Fis1, Drp1, and Opa1 in apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI270

Gag3p, an outer membrane protein required for fission of mitochondrial tubules

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI270

Dnm1p GTPase-mediated mitochondrial fission is a multi-step process requiring the novel integral membrane component Fis1p

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI270

Mdv1p is a WD repeat protein that interacts with the dynamin-related GTPase, Dnm1p, to trigger mitochondrial division

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI270

The WD40 protein Caf4p is a component of the mitochondrial fission machinery and recruits Dnm1p to mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI270

The WD-repeats of Net2p interact with Dnm1p and Fis1p to regulate division of mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI270

The WD repeat protein, Mdv1p, functions as a molecular adaptor by interacting with Dnm1p and Fis1p during mitochondrial fission

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI270

The solution structure of human mitochondria fission protein Fis1 reveals a novel TPR-like helix bundle

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI270

Cytosolic domain of the human mitochondrial fission protein fis1 adopts a TPR fold

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI270

TPR proteins: the versatile helix

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI270

Structural basis of mitochondrial tethering by mitofusin complexes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI270

The role of dynamin-related protein 1, a mediator of mitochondrial fission, in apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI270

Movement of Bax from the cytosol to mitochondria during apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI270

Structure of Bax: coregulation of dimer formation and intracellular localization

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI270

Mitochondria and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI270

Mitochondrial fusion and fission in the control of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI270

Spatial and temporal association of Bax with mitochondrial fission sites, Drp1, and Mfn2 during apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI270

Drp-1-dependent division of the mitochondrial network blocks intraorganellar Ca2+ waves and protects against Ca2+-mediated apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI270

Quantitation of mitochondrial dynamics by photolabeling of individual organelles shows that mitochondrial fusion is blocked during the Bax activation phase of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI270

The causes of Charcot-Marie-Tooth disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI270

Charcot-Marie-Tooth disease: an update

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI270

Mutations in the mitochondrial GTPase mitofusin 2 cause Charcot-Marie-Tooth neuropathy type 2A

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI270

OPA1 (Kjer type) dominant optic atrophy: a novel mitochondrial disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI270

OPA1, encoding a dynamin-related GTPase, is mutated in autosomal dominant optic atrophy linked to chromosome 3q28

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI270

Nuclear gene OPA1, encoding a mitochondrial dynamin-related protein, is mutated in dominant optic atrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI270

eOPA1: an online database for OPA1 mutations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI270

Deletion of the OPA1 gene in a dominant optic atrophy family: evidence that haploinsufficiency is the cause of disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI270

Mitochondrial DNA content is decreased in autosomal dominant optic atrophy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI270

Deficit of in vivo mitochondrial ATP production in OPA1-related dominant optic atrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI270

Nerve growth factor signaling regulates motility and docking of axonal mitochondria.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI270

The importance of dendritic mitochondria in the morphogenesis and plasticity of spines and synapses

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI270

Axonal transport of mitochondria to synapses depends on milton, a novel Drosophila protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI270

Synaptic mitochondria are critical for mobilization of reserve pool vesicles at Drosophila neuromuscular junctions

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI270

Dysregulation of HSG triggers vascular proliferative disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI270

Mitofusin-2 determines mitochondrial network architecture and mitochondrial metabolism. A novel regulatory mechanism altered in obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI270

The Charcot-Marie-Tooth type 2A gene product, Mfn2, up-regulates fuel oxidation through expression of OXPHOS system

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI270

Mitochondrial fusion intermediates revealed in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI270

21 January 2018

Identifiers

DOI

10.1093/HMG/DDI270

1 reference

13 August 2017

1 reference

PubMed ID

16244327