(Q36294824)

English

Benzbromarone, an old uricosuric drug, inhibits human fatty acid binding protein 4 in vitro and lowers the blood glucose level in db/db mice

scientific article published on 30 September 2013

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Benzbromarone, an old uricosuric drug, inhibits human fatty acid binding protein 4 in vitro and lowers the blood glucose level in db/db mice (English)

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

0 references

0 references

author name string

Hai-yan Cai

1

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Ting Wang

2

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Jian-chun Zhao

3

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Peng Sun

4

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Gui-rui Yan

5

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Hai-peng Ding

6

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Ying-xia Li

7

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

He-yao Wang

8

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Wei-liang Zhu

9

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Kai-xian Chen

10

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

publication date

30 September 2013

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Acta Pharmacologica Sinica

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

34

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

11

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

1397-1402

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

https://scigraph.springernature.com/pub.10.1038/aps.2013.97

0 references

Pharmacological inhibition of diacylglycerol acyltransferase 1 reduces body weight gain, hyperlipidemia, and hepatic steatosis in db/db mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4651057

30 September 2017

Identification and Characterization of a Small Molecule Inhibitor of Fatty Acid Binding Proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4651057

30 September 2017

N-Benzyl-indolo carboxylic acids: Design and synthesis of potent and selective adipocyte fatty-acid binding protein (A-FABP) inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4651057

30 September 2017

Crystal structure of the peroxisome proliferator-activated receptor gamma (PPARgamma) ligand binding domain complexed with a novel partial agonist: a new region of the hydrophobic pocket could be exploited for drug design

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4651057

30 September 2017

A benefit-risk assessment of benzbromarone in the treatment of gout. Was its withdrawal from the market in the best interest of patients?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4651057

30 September 2017

Treatment of diabetes and atherosclerosis by inhibiting fatty-acid-binding protein aP2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4651057

30 September 2017

Potent and selective biphenyl azole inhibitors of adipocyte fatty acid binding protein (aFABP)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4651057

30 September 2017

Expression, purification, crystallization and structure of human adipocyte lipid-binding protein (aP2)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4651057

30 September 2017

PPARgamma agonism increases rat adipose tissue lipolysis, expression of glyceride lipases, and the response of lipolysis to hormonal control

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4651057

30 September 2017

A genetic variant at the fatty acid-binding protein aP2 locus reduces the risk for hypertriglyceridemia, type 2 diabetes, and cardiovascular disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4651057

30 September 2017

Fenofibrate prevents Rosiglitazone-induced body weight gain in ob/ob mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4651057

30 September 2017

Lack of macrophage fatty-acid-binding protein aP2 protects mice deficient in apolipoprotein E against atherosclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4651057

30 September 2017

Improved glucose and lipid metabolism in genetically obese mice lacking aP2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4651057

30 September 2017

Adipocyte lipid-binding protein complexed with arachidonic acid. Titration calorimetry and X-ray crystallographic studies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4651057

30 September 2017

Molecular cloning of mRNA from 3T3 adipocytes. Regulation of mRNA content for glycerophosphate dehydrogenase and other differentiation-dependent proteins during adipocyte development.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4651057

30 September 2017

Adipocyte P2 gene: developmental expression and homology of 5'-flanking sequences among fat cell-specific genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4651057

30 September 2017

Toxicological studies on a benzofurane derivative. II. Demonstration of peroxisome proliferation in rat liver

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4651057

30 September 2017

Benzbromarone: a review of its pharmacological properties and therapeutic use in gout and hyperuricaemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4651057

30 September 2017

Activating effect of benzbromarone, a uricosuric drug, on peroxisome proliferator-activated receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4651057

29 June 2018

Targeted disruption of the adipocyte lipid-binding protein (aP2 protein) gene impairs fat cell lipolysis and increases cellular fatty acid levels.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4651057

29 June 2018

Substituted benzylamino-6-(trifluoromethyl)pyrimidin-4(1H)-ones: a novel class of selective human A-FABP inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4651057

22 September 2018

Discovery of inhibitors of human adipocyte fatty acid-binding protein, a potential type 2 diabetes target

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4651057

22 September 2018

Uncoupling of obesity from insulin resistance through a targeted mutation in aP2, the adipocyte fatty acid binding protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4651057

22 September 2018

Discovery of highly selective inhibitors of human fatty acid binding protein 4 (FABP4) by virtual screening

1 reference

https://pubmed.ncbi.nlm.nih.gov/24077632

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Improved Glucose and Lipid Metabolism in Genetically Obese Mice Lacking aP2

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2013.97

7 January 2021

based on heuristic

inferred from DOI database lookup

Automated docking using a Lamarckian genetic algorithm and an empirical binding free energy function

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2013.97

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1038/APS.2013.97

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Dimensions Publication ID

0 references

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

ResearchGate publication ID

0 references

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