(Q36296183)

English

Breast cancer resistance protein (ABCG2) determines distribution of genistein phase II metabolites: reevaluation of the roles of ABCG2 in the disposition of genistein

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Breast cancer resistance protein (ABCG2) determines distribution of genistein phase II metabolites: reevaluation of the roles of ABCG2 in the disposition of genistein (English)

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

author name string

Zhen Yang

1

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Wei Zhu

2

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Song Gao

3

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Taijun Yin

4

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Wen Jiang

5

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Ming Hu

6

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

publication date

26 June 2012

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Drug Metabolism and Disposition

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

40

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

10

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

1883-1893

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Bioavailability and pharmacokinetics of genistein: mechanistic studies on its ADME.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463821

30 September 2017

First-pass metabolism via UDP-glucuronosyltransferase: a barrier to oral bioavailability of phenolics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463821

30 September 2017

Structure and Function of the Human Breast Cancer Resistance Protein (BCRP/ABCG2)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463821

30 September 2017

Breast cancer resistance protein (BCRP) and sulfotransferases contribute significantly to the disposition of genistein in mouse intestine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463821

30 September 2017

Simultaneous determination of genistein and its four phase II metabolites in blood by a sensitive and robust UPLC-MS/MS method: Application to an oral bioavailability study of genistein in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463821

30 September 2017

Biopharmaceutical and pharmacokinetic characterization of matrine as determined by a sensitive and robust UPLC-MS/MS method

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463821

30 September 2017

Interplay of transporters and enzymes in drug and metabolite processing.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463821

30 September 2017

Predicting drug-drug interactions: an FDA perspective

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463821

30 September 2017

Multi-targeted therapy of cancer by genistein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463821

30 September 2017

New era in drug interaction evaluation: US Food and Drug Administration update on CYP enzymes, transporters, and the guidance process

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463821

30 September 2017

Effect of breast cancer resistance protein (Bcrp/Abcg2) on the disposition of phytoestrogens

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463821

30 September 2017

Role of breast cancer resistance protein (Bcrp1/Abcg2) in the extrusion of glucuronide and sulfate conjugates from enterocytes to intestinal lumen

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463821

30 September 2017

Absorption and metabolism of flavonoids in the caco-2 cell culture model and a perused rat intestinal model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463821

30 September 2017

Mechanism of L-alpha-methyldopa transport through a monolayer of polarized human intestinal epithelial cells (Caco-2).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463821

29 June 2018

Identification and quantification of daidzein-7-glucuronide-4'-sulfate, genistein-7-glucuronide-4'-sulfate and genistein-4',7-diglucuronide as major metabolites in human plasma after administration of kinako

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463821

22 September 2018

Functional characterization of multidrug resistance-associated protein 3 (mrp3/abcc3) in the basolateral efflux of glucuronide conjugates in the mouse small intestine.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463821

22 September 2018

Targeted metabolomics identifies glucuronides of dietary phytoestrogens as a major class of MRP3 substrates in vivo.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463821

22 September 2018

Dose-dependent absorption, metabolism, and excretion of genistein in rats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463821

22 September 2018

Genistein- and daidzein 7-O-beta-D-glucuronic acid retain the ability to inhibit copper-mediated lipid oxidation of low density lipoprotein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463821

22 September 2018

Differential biliary excretion of genistein metabolites following intraduodenal and intravenous infusion of genistin in female rats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463821

22 September 2018

Metabolic phenotype of isoflavones differ among female rats, pigs, monkeys, and women.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463821

22 September 2018

Disposition of flavonoids via recycling: comparison of intestinal versus hepatic disposition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463821

22 September 2018

Expression, localization, and functional characteristics of breast cancer resistance protein in Caco-2 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463821

22 September 2018

Absorption and metabolism of genistein and its five isoflavone analogs in the human intestinal Caco-2 model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463821

22 September 2018

Phytoestrogens/flavonoids reverse breast cancer resistance protein/ABCG2-mediated multidrug resistance.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463821

22 September 2018

Disposition of flavonoids via enteric recycling: enzyme-transporter coupling affects metabolism of biochanin A and formononetin and excretion of their phase II conjugates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463821

22 September 2018

Metabolism of flavonoids via enteric recycling: role of intestinal disposition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463821

22 September 2018

Absolute bioavailability of [14C] genistein in the rat; plasma pharmacokinetics of parent compound, genistein glucuronide and total radioactivity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463821

22 September 2018

Steroid and bile acid conjugates are substrates of human multidrug-resistance protein (MRP) 4 (ATP-binding cassette C4).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463821

22 September 2018

Bioavailability of the Glucuronide and Sulfate Conjugates of Genistein and Daidzein in Breast Cancer Resistance Protein 1 Knockout Mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463821

5 December 2018

Efflux transport is an important determinant of ethinylestradiol glucuronide and ethinylestradiol sulfate pharmacokinetics

1 reference

https://pubmed.ncbi.nlm.nih.gov/22736306

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enhancement of oral bioavailability of 20(S)-ginsenoside Rh2 through improved understanding of its absorption and efflux mechanisms

1 reference

https://pubmed.ncbi.nlm.nih.gov/22736306

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics of [(14)C]Genistein in the rat: gender-related differences, potential mechanisms of biological action, and implications for human health

1 reference

https://pubmed.ncbi.nlm.nih.gov/22736306

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Urinary pharmacokinetics of the glucuronide and sulfate conjugates of genistein and daidzein

1 reference

https://pubmed.ncbi.nlm.nih.gov/22736306

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intestinal uptake and biliary excretion of the isoflavone genistein in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/22736306

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Daidzein and genistein glucuronides in vitro are weakly estrogenic and activate human natural killer cells at nutritionally relevant concentrations

1 reference

https://pubmed.ncbi.nlm.nih.gov/22736306

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Altered hepatobiliary disposition of 5 (and 6)-carboxy-2',7'-dichlorofluorescein in Abcg2 (Bcrp1) and Abcc2 (Mrp2) knockout mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/22736306

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of drug transporter expression in human intestinal Caco-2 cells by real-time PCR

1 reference

https://pubmed.ncbi.nlm.nih.gov/22736306

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1124/DMD.111.043901

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

ResearchGate publication ID

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