(Q36301466)

English

Insulin-like growth factor II signaling in neoplastic proliferation is blocked by transgenic expression of the metalloproteinase inhibitor TIMP-1.

scientific article published in August 1999

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Statements

scholarly article

1 reference

Europe PubMed Central

13 August 2017

Insulin-like growth factor II signaling in neoplastic proliferation is blocked by transgenic expression of the metalloproteinase inhibitor TIMP-1. (English)

1 reference

Europe PubMed Central

13 August 2017

1 reference

based on heuristic

inferred from title

author name string

D C Martin

1

1 reference

Europe PubMed Central

13 August 2017

J L Fowlkes

2

1 reference

Europe PubMed Central

13 August 2017

B Babic

3

1 reference

Europe PubMed Central

13 August 2017

R Khokha

4

1 reference

Europe PubMed Central

13 August 2017

language of work or name

0 references

publication date

1 August 1999

1 reference

Europe PubMed Central

13 August 2017

number of pages

12

1 reference

based on heuristic

inferred from page(s)

Journal of Cell Biology

1 reference

Europe PubMed Central

13 August 2017

146

1 reference

Europe PubMed Central

13 August 2017

881-892

1 reference

Europe PubMed Central

13 August 2017

4

1 reference

Europe PubMed Central

13 August 2017

describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2156132/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

What is the function of IGF-II in postnatal life? Answers from transgenic mouse models.

1 reference

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1 reference

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1 reference

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1 reference

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Protease-resistant form of insulin-like growth factor-binding protein 5 is an inhibitor of insulin-like growth factor-I actions on porcine smooth muscle cells in culture.

1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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30 September 2017

Tissue inhibitor of metalloproteinases (TIMP, aka EPA): structure, control of expression and biological functions

1 reference

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30 September 2017

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1 reference

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30 September 2017

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1 reference

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Insulin-like growth factors and their binding proteins: biological actions

1 reference

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Loss of heterozygosity of imprinted genes in SV40 t/T antigen-induced hepatocellular carcinomas

1 reference

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1 reference

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Mammary cancer in transgenic mice expressing insulin-like growth factor II (IGF-II)

1 reference

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Collagenase expression in transgenic mouse skin causes hyperkeratosis and acanthosis and increases susceptibility to tumorigenesis

1 reference

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Insulin-like growth factor-I receptor. Its role in cell proliferation, apoptosis, and tumorigenicity

1 reference

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Proteolytic cleavage of insulin-like growth factor binding protein 4 (IGFBP-4). Localization of cleavage site to non-homologous region of native IGFBP-4.

1 reference

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Cleavage analysis of insulin-like growth factor (IGF)-dependent IGF-binding protein-4 proteolysis and expression of protease-resistant IGF-binding protein-4 mutants

1 reference

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Protease-induced alteration of insulin-like growth factor binding protein-3 as detected by radioimmunoassay. Agreement with ligand blotting data.

1 reference

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Matrix metalloproteinases degrade insulin-like growth factor-binding protein-3 in dermal fibroblast cultures

1 reference

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Mammary gland tumor formation in transgenic mice overexpressing stromelysin-1.

1 reference

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Identification of the p53 protein domain involved in formation of the simian virus 40 large T-antigen-p53 protein complex

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SV40 large tumor antigen forms a specific complex with the product of the retinoblastoma susceptibility gene

1 reference

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Proteinases and extracellular matrix remodeling

1 reference

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1 reference

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Extracellular matrix regulation of growth factor and protease activity

1 reference

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1 reference

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1 reference

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The matrix-degrading metalloproteinases

1 reference

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1 reference

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1 reference

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Insulin-like growth factor II (IGF-II) secreted from HepG2 human hepatocellular carcinoma cells shows angiogenic activity.

1 reference

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1 reference

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29 June 2018

ECM and cell surface proteolysis: regulating cellular ecology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2156132

29 June 2018

IGF-I supports the survival and/or differentiation of multiple types of central nervous system neurons.

1 reference

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29 June 2018

A second signal supplied by insulin-like growth factor II in oncogene-induced tumorigenesis

1 reference

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The insulin-like growth factor I receptor protects tumor cells from apoptosis in vivo.

1 reference

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29 June 2018

Acid-activated insulin-like growth factor-binding protein-3 proteolysis in normal and transformed cells. Role of cathepsin D.

1 reference

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29 June 2018

Comparison of in vivo effects of insulin-like growth factors I and II and of growth hormone in hypophysectomized rats

1 reference

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1 reference

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29 June 2018

Antisense RNA-induced reduction in murine TIMP levels confers oncogenicity on Swiss 3T3 cells

1 reference

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Expression of somatomedin/insulin-like growth factor messenger ribonucleic acids in the human fetus: identification, characterization, and tissue distribution.

1 reference

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29 June 2018

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1 reference

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29 June 2018

Tissue-specific expression of insulin-like growth factor binding protein-3 protease activity during rat pregnancy

1 reference

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29 June 2018

Measurement and characterization of insulin-like growth factor binding protein-3 in human biological fluids: discrepancies between radioimmunoassay and ligand blotting

1 reference

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29 June 2018

Insulinlike growth factor-binding protein proteolysis an emerging paradigm in insulinlike growth factor physiology.

1 reference

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22 September 2018

Transgenic TIMP-1 inhibits simian virus 40 T antigen-induced hepatocarcinogenesis by impairment of hepatocellular proliferation and tumor angiogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2156132

22 September 2018

A dominant negative mutant of the insulin-like growth factor-I receptor inhibits the adhesion, invasion, and metastasis of breast cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2156132

22 September 2018

The role of the insulin-like growth factor I receptor in transformation and apoptosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2156132

22 September 2018

Inhibition of tumor growth and metastasis of human breast cancer cells transfected with tissue inhibitor of metalloproteinase 4.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2156132

22 September 2018

Hepatocarcinogenesis in woodchuck hepatitis virus/c-myc mice: sustained cell proliferation and biphasic activation of insulin-like growth factor II.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2156132

22 September 2018

Regulation of insulin-like growth factor II P3 promotor by p53: a potential mechanism for tumorigenesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2156132

22 September 2018

Inducible formation of liver tumors in transgenic mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2156132

22 September 2018

Expression of insulin-like growth factor II (IGF-II) in human hepatocellular carcinomas: an immunohistochemical study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2156132

22 September 2018

Altered body composition and increased frequency of diverse malignancies in insulin-like growth factor-II transgenic mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2156132

22 September 2018

Insulin-like growth factor binding protein-3 is functionally altered in pregnancy plasma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2156132

22 September 2018

Circulating concentrations of insulin-like growth factor I and risk of breast cancer

1 reference

https://api.crossref.org/works/10.1083%2FJCB.146.4.881

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Quantification of insulin-like growth factor I (IGF-I) without interference by IGF binding proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/10459021

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reactivation of the maternally imprinted IGF2 allele in TGFalpha induced hepatocellular carcinomas in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/10459021

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tissue distribution of insulin-like growth factor I and II messenger ribonucleic acid in the adult rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/10459021

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Altered tumor growth and metastasis of a T-cell lymphoma in Timp-1 transgenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/10459021

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein and messenger ribonucleic acid (mRNA) for the type 1 insulin-like growth factor (IGF) receptor is decreased and IGF-II mRNA is increased in human prostate carcinoma compared to benign prostate epithelium

1 reference

https://pubmed.ncbi.nlm.nih.gov/10459021

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proteolysis of insulin-like growth factor binding protein-3 during rat pregnancy: a role for matrix metalloproteinases

1 reference

https://pubmed.ncbi.nlm.nih.gov/10459021

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Suppression of the tumorigenic and metastatic abilities of murine B16-F10 melanoma cells in vivo by the overexpression of the tissue inhibitor of the metalloproteinases-1

1 reference

https://pubmed.ncbi.nlm.nih.gov/10459021

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reactivation of insulin-like growth factor II during hepatocarcinogenesis in transgenic mice suggests a role in malignant growth

1 reference

https://pubmed.ncbi.nlm.nih.gov/10459021

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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1 reference

https://pubmed.ncbi.nlm.nih.gov/10459021

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of angiogenesis by tissue inhibitor of metalloproteinase-3

1 reference

https://pubmed.ncbi.nlm.nih.gov/10459021

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of SV40 T antigen-induced hepatocellular carcinoma in TIMP-1 transgenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/10459021

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin-like growth factor binding protein (IGFBP) substrate zymography. A new tool to identify and characterize IGFBP-degrading proteinases

1 reference

https://pubmed.ncbi.nlm.nih.gov/10459021

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin-like growth factor (IGF) binding to cell monolayers is directly modulated by the addition of IGF-binding proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/10459021

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genomic imprinting and Igf2 influence liver tumorigenesis and loss of heterozygosity in SV40 T antigen transgenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/10459021

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1083/JCB.146.4.881

1 reference

Europe PubMed Central

13 August 2017

1 reference

Europe PubMed Central

13 August 2017

1 reference

Europe PubMed Central

13 August 2017

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