(Q36305346)

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A humanized single-chain antibody against beta 3 integrin inhibits pulmonary metastasis by preferentially fragmenting activated platelets in the tumor microenvironment.

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22879538%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

A humanized single-chain antibody against beta 3 integrin inhibits pulmonary metastasis by preferentially fragmenting activated platelets in the tumor microenvironment (English)

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22879538%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

Thomas Wisniewski

9

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22879538%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

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Wei Zhang

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22879538%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

Suying Dang

2

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22879538%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

Tao Hong

3

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22879538%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

Jian Tang

4

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22879538%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

Jing Fan

5

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22879538%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

Dawei Bu

6

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22879538%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

Yanjie Sun

7

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22879538%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

Zhugang Wang

8

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22879538%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

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9 August 2012

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22879538%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22879538%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

120

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22879538%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

14

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22879538%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

2889-2898

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22879538%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

Effect of daily aspirin on risk of cancer metastasis: a study of incident cancers during randomised controlled trials

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466970

30 September 2017

A humanized single-chain variable fragment antibody against beta3 integrin in Escherichia coli

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466970

30 September 2017

Engagement of αIIbβ3 (GPIIb/IIIa) with ανβ3 integrin mediates interaction of melanoma cells with platelets: a connection to hematogenous metastasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466970

30 September 2017

Direct signaling between platelets and cancer cells induces an epithelial-mesenchymal-like transition and promotes metastasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466970

30 September 2017

Contribution of platelets to tumour metastasis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466970

30 September 2017

Specific cross-reaction of anti-dsDNA antibody with platelet integrin GPIIIa49-66

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466970

30 September 2017

Dissolution of arterial platelet thrombi in vivo with a bifunctional platelet GPIIIa49-66 ligand which specifically targets the platelet thrombus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466970

30 September 2017

Role of molecular mimicry of hepatitis C virus protein with platelet GPIIIa in hepatitis C-related immunologic thrombocytopenia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466970

30 September 2017

The role of platelet activation in tumor metastasis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466970

30 September 2017

Platelet fragmentation requires a specific structural conformation of human monoclonal antibody against beta3 integrin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466970

30 September 2017

Inhibition of platelet function: does it offer a chance of better cancer progression control?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466970

30 September 2017

Platelet function and antiplatelet therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466970

30 September 2017

Platelet glycoprotein Ib alpha supports experimental lung metastasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466970

30 September 2017

Thrombocytosis as a prognostic factor for survival in patients with metastatic renal cell carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466970

30 September 2017

Blockade of GpIIb/IIIa inhibits the release of vascular endothelial growth factor (VEGF) from tumor cell-activated platelets and experimental metastasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466970

30 September 2017

Role of molecular mimicry to HIV-1 peptides in HIV-1-related immunologic thrombocytopenia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466970

30 September 2017

Coagulation facilitates tumor cell spreading in the pulmonary vasculature during early metastatic colony formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466970

30 September 2017

Complement-independent Ab-induced peroxide lysis of platelets requires 12-lipoxygenase and a platelet NADPH oxidase pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466970

30 September 2017

Inhibition of tumor cell-induced platelet aggregation and lung metastasis by the oral GpIIb/IIIa antagonist XV454.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466970

30 September 2017

Platelet glycoprotein IIb/IIIa antagonists: lessons learned from clinical trials and future directions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466970

30 September 2017

Effect of antihemostatic agents on experimental tumor dissemination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466970

30 September 2017

Complement-independent, peroxide-induced antibody lysis of platelets in HIV-1-related immune thrombocytopenia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466970

30 September 2017

Perspectives series: cell adhesion in vascular biology. Integrin signaling in vascular biology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466970

30 September 2017

Role of plasma, platelets, and endothelial cells in tumor metastasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466970

30 September 2017

Lack of effect of in vivo prostacyclin on the development of pulmonary metastases in mice following intravenous injection of CT26 colon carcinoma, Lewis lung carcinoma, or B16 amelanotic melanoma cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466970

30 September 2017

Role of adhesive proteins in platelet tumor interaction in vitro and metastasis formation in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466970

30 September 2017

PADGEM-dependent adhesion of platelets to monocytes and neutrophils is mediated by a lineage-specific carbohydrate, LNF III (CD15)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466970

30 September 2017

Platelets and fibrin(ogen) increase metastatic potential by impeding natural killer cell-mediated elimination of tumor cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466970

22 September 2018

Thrombocytosis associated with poor prognosis in patients with esophageal carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466970

22 September 2018

Role of platelets in tumor cell metastases

1 reference

https://pubmed.ncbi.nlm.nih.gov/22879538

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prognostic impact of thrombocytosis in resectable non-small cell lung cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/22879538

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A simple method for human peripheral blood monocyte isolation

1 reference

https://pubmed.ncbi.nlm.nih.gov/22879538

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of alphaII(b)beta3 integrin in prostate cancer metastasis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22879538

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lysis of tumor cells by natural killer cells in mice is impeded by platelets

1 reference

https://pubmed.ncbi.nlm.nih.gov/22879538

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The value of preoperative platelet count in the prediction of cervical involvement and poor prognostic variables in patients with endometrial carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/22879538

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1182/BLOOD-2012-04-425207

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22879538%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22879538%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22879538%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

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