(Q36307323)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16273073%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

review article

1 reference

title

Activation of the mammalian immune system by siRNAs (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16273073%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

author name string

Bryan R G Williams

series ordinal

2

1 reference

13 August 2017

language of work or name

1 reference

1 November 2005

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16273073%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16273073%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

volume

23

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16273073%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

issue

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16273073%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

page(s)

1399-1405

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16273073%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/nbt1161

8 January 2020

exact match

0 references

cites work

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21 January 2018

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21 January 2018

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RNA silencing in plants

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Perspective: machines for RNAi

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Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

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RNAi therapeutics: how likely, how soon?

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21 January 2018

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Small interfering RNAs mediate sequence-independent gene suppression and induce immune activation by signaling through toll-like receptor 3.

21 January 2018

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RNA interference in biology and disease

21 January 2018

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Activation of the interferon system by short-interfering RNAs

21 January 2018

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Interferon induction by siRNAs and ssRNAs synthesized by phage polymerase

21 January 2018

1 reference

Nonspecific, concentration-dependent stimulation and repression of mammalian gene expression by small interfering RNAs (siRNAs).

21 January 2018

1 reference

Toll-like receptors in innate immunity

21 January 2018

1 reference

Sequence-specific potent induction of IFN-alpha by short interfering RNA in plasmacytoid dendritic cells through TLR7

21 January 2018

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Induction of inflammatory cytokines and interferon responses by double-stranded and single-stranded siRNAs is sequence-dependent and requires endosomal localization

21 January 2018

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21 January 2018

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Small anti-viral compounds activate immune cells via the TLR7 MyD88-dependent signaling pathway

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Toll-like receptor control of the adaptive immune responses

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IPC: professional type 1 interferon-producing cells and plasmacytoid dendritic cell precursors

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Differential signaling by CpG DNA in DCs and B cells: not just TLR9

21 January 2018

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The Toll‐like receptor 7 (TLR7)‐specific stimulus loxoribine uncovers a strong relationship within the TLR7, 8 and 9 subfamily

21 January 2018

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Interferon-alpha and interleukin-12 are induced differentially by Toll-like receptor 7 ligands in human blood dendritic cell subsets

21 January 2018

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Human dendritic cells: potent antigen-presenting cells at the crossroads of innate and adaptive immunity

21 January 2018

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Quantitative expression of toll-like receptor 1-10 mRNA in cellular subsets of human peripheral blood mononuclear cells and sensitivity to CpG oligodeoxynucleotides

21 January 2018

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Expression and function of Toll-like receptors in eosinophils: activation by Toll-like receptor 7 ligand.

21 January 2018

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TLR7/8-mediated activation of human NK cells results in accessory cell-dependent IFN-gamma production.

21 January 2018

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Direct stimulation of human T cells via TLR5 and TLR7/8: flagellin and R-848 up-regulate proliferation and IFN-gamma production by memory CD4+ T cells.

21 January 2018

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Plasmacytoid dendritic cells control TLR7 sensitivity of naive B cells via type I IFN.

21 January 2018

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Use of murine embryonic fibroblasts to define Toll-like receptor activation and specificity.

21 January 2018

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The evolution of vertebrate Toll-like receptors

21 January 2018

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21 January 2018

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21 January 2018

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Human peripheral blood cells differentially recognize and respond to two distinct CPG motifs

21 January 2018

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Toll-like receptor 9 binds single-stranded CpG-DNA in a sequence- and pH-dependent manner.

21 January 2018

1 reference

Spatiotemporal regulation of MyD88-IRF-7 signalling for robust type-I interferon induction

21 January 2018

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Therapeutic silencing of an endogenous gene by systemic administration of modified siRNAs

21 January 2018

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CpG RNA: identification of novel single-stranded RNA that stimulates human CD14+CD11c+ monocytes

21 January 2018

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Crystal structure of human toll-like receptor 3 (TLR3) ectodomain

21 January 2018

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Potent and persistent in vivo anti-HBV activity of chemically modified siRNAs

21 January 2018

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LNA (Locked Nucleic Acids): Synthesis of the adenine, cytosine, guanine, 5-methylcytosine, thymine and uracil bicyclonucleoside monomers, oligomerisation, and unprecedented nucleic acid recognition

21 January 2018

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siRNA function in RNAi: a chemical modification analysis

21 January 2018

1 reference

RNAi in human cells: basic structural and functional features of small interfering RNA.

21 January 2018

1 reference

The critical DNA flanking sequences of a CpG oligodeoxynucleotide, but not the 6 base CpG motif, can be replaced with RNA without quantitative or qualitative changes in Toll-like receptor 9-mediated activity

21 January 2018

1 reference

Decoding the patterns of self and nonself by the innate immune system

21 January 2018

1 reference

Innate immune recognition of nucleic acids: beyond toll-like receptors

21 January 2018

1 reference

Dinucleotide relative abundance extremes: a genomic signature

21 January 2018

1 reference

Toll-like receptor 9-dependent and -independent dendritic cell activation by chromatin-immunoglobulin G complexes.

21 January 2018

1 reference

Cutting edge: innate immune system discriminates between RNA containing bacterial versus eukaryotic structural features that prime for high-level IL-12 secretion by dendritic cells

21 January 2018

1 reference

Toll-like receptor-dependent activation of several human blood cell types by protamine-condensed mRNA.

21 January 2018

1 reference

mRNA is an endogenous ligand for Toll-like receptor 3.

21 January 2018

1 reference

Suppression of RNA recognition by Toll-like receptors: the impact of nucleoside modification and the evolutionary origin of RNA

21 January 2018

1 reference

Distinct and essential roles of transcription factors IRF-3 and IRF-7 in response to viruses for IFN-alpha/beta gene induction

21 January 2018

1 reference

Subcellular localization of Toll-like receptor 3 in human dendritic cells

21 January 2018

1 reference

Activation of airway epithelial cells by toll-like receptor agonists

21 January 2018

1 reference

Distinct poly(I-C) and virus-activated signaling pathways leading to interferon-beta production in hepatocytes

21 January 2018

1 reference

Synergistic activation of innate immunity by double-stranded RNA and CpG DNA promotes enhanced antitumor activity

21 January 2018

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Replication-dependent potent IFN-alpha induction in human plasmacytoid dendritic cells by a single-stranded RNA virus

21 January 2018

1 reference

The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses

21 January 2018

1 reference

The V proteins of paramyxoviruses bind the IFN-inducible RNA helicase, mda-5, and inhibit its activation of the IFN-beta promoter

21 January 2018

1 reference

Cell type-specific involvement of RIG-I in antiviral response

21 January 2018

1 reference

Atelocollagen-mediated synthetic small interfering RNA delivery for effective gene silencing in vitro and in vivo

21 January 2018

1 reference

MicroRNA biogenesis: coordinated cropping and dicing

21 January 2018

1 reference

CpG motifs in bacterial DNA trigger direct B-cell activation

21 January 2018

1 reference

A Toll-like receptor recognizes bacterial DNA

21 January 2018

1 reference

Role of Toll-like receptors in antisense and siRNA [corrected].

21 January 2018

1 reference

Sequence-dependent stimulation of the mammalian innate immune response by synthetic siRNA

21 January 2018

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Lack of interferon response in animals to naked siRNAs

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Why is CpG suppressed in the genomes of virtually all small eukaryotic viruses but not in those of large eukaryotic viruses?

1 reference