(Q36311608)

13 August 2017

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title

Non-linear mixed effects modeling - from methodology and software development to driving implementation in drug development science (English)

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13 August 2017

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Goonaseelan Colin Pillai

series ordinal

1

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13 August 2017

France Mentré

series ordinal

2

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13 August 2017

Jean-Louis Steimer

series ordinal

3

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13 August 2017

publication date

1 April 2005

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Journal of Pharmacokinetics and Pharmacodynamics

13 August 2017

published in

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13 August 2017

volume

32

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13 August 2017

issue

2

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13 August 2017

page(s)

161-183

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Improved computer-assisted digoxin therapy. A method using feedback of measured serum digoxin concentrations

13 August 2017

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Use of a pharmacokinetic/pharmacodynamic model to design an optimal dose input profile

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A Two-Step Iterative Algorithm For Estimation In Nonlinear Mixed-Effect Models With An Evaluation In Population Pharmacokinetics

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Further Developments of the Fisher Information Matrix in Nonlinear Mixed Effects Models with Evaluation in Population Pharmacokinetics

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The estimation of population pharmacokinetic parameters using an EM algorithm.

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Implications of an alternative approach to dose-response trials

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Comparison of population pharmacokinetic modeling methods using simulated data: results from the Population Modeling Workgroup

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Learning versus confirming in clinical drug development

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12 December 2020

10.1007/S10928-005-0062-Y

Identifiers

DOI

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13 August 2017

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