(Q36318525)

13 August 2017

1 reference

title

Targeting histone deacetylase 2 in chronic obstructive pulmonary disease treatment (English)

1 reference

chronic obstructive pulmonary disease

13 August 2017

1 reference

Peter J Barnes

1

1 reference

PubMed ID

16300464

13 August 2017

language of work or name

English

0 references

publication date

1 December 2005

1 reference

Expert Opinion on Therapeutic Targets

13 August 2017

1 reference

13 August 2017

9

1 reference

13 August 2017

6

1 reference

13 August 2017

1111-1121

1 reference

The global burden of disease, 1990–2020

13 August 2017

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.6.1111

Chronic obstructive pulmonary disease: molecular and cellularmechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.6.1111

COPD: current therapeutic interventions and future approaches

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.6.1111

The effects of inhaled corticosteroids in chronic obstructive pulmonary disease: a systematic review of randomized placebo-controlled trials

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.6.1111

Prospects for new drugs for chronic obstructive pulmonary disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.6.1111

Mediators of chronic obstructive pulmonary disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.6.1111

Transcription factors and asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.6.1111

Histone acetylation and deacetylation: importance in inflammatory lung diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.6.1111

The role of histones in the maintenance of chromatin structure

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.6.1111

The transcriptional coactivators p300 and CBP are histone acetyltransferases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.6.1111

Histone acetyltransferases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.6.1111

Cloning and functional characterization of HDAC11, a novel member of the human histone deacetylase family

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.6.1111

Glucocorticoid receptor recruitment of histone deacetylase 2 inhibits interleukin-1beta-induced histone H4 acetylation on lysines 8 and 12.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.6.1111

Histone deacetylases (HDACs): characterization of the classical HDAC family

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.6.1111

HDAC's at work: everyone doing their part

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.6.1111

Ligand-dependent nuclear receptor corepressor LCoR functions by histone deacetylase-dependent and -independent mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.6.1111

From discovery to the coming generation of histone deacetylase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.6.1111

Theophylline restores histone deacetylase activity and steroid responses in COPD macrophages.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.6.1111

The effect of oxidative stress on histone acetylation and IL-8 release

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.6.1111

Duration of nuclear NF-kappaB action regulated by reversible acetylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.6.1111

The phosphorylation status of nuclear NF-kappa B determines its association with CBP/p300 or HDAC-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.6.1111

Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.6.1111

Diversity in the Sir2 family of protein deacetylases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.6.1111

Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.6.1111

The emerging therapeutic potential of sirtuin-interacting drugs: from cell death to lifespan extension

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.6.1111

Cigarette smoke alters chromatin remodeling and induces proinflammatory genes in rat lungs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.6.1111

Redox modulation of chromatin remodeling: impact on histone acetylation and deacetylation, NF-kappaB and pro-inflammatory gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.6.1111

Oxidative stress reduces histone deacetylase 2 activity and enhances IL-8 gene expression: role of tyrosine nitration

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.6.1111

Specific nitration at tyrosine 430 revealed by high resolution mass spectrometry as basis for redox regulation of bovine prostacyclin synthase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.6.1111

Modifications of glyceraldehyde-3-phosphate dehydrogenase induced by increasing concentrations of peroxynitrite: early recognition by 20S proteasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.6.1111

Increased leukotriene B4 and 8-isoprostane in exhaled breath condensate of patients with exacerbations of COPD.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.6.1111

4-Hydroxy-2-nonenal, a specific lipid peroxidation product, is elevated in lungs of patients with chronic obstructive pulmonary disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.6.1111

Inflammatory mediator mRNA expression by adenovirus E1A-transfected bronchial epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.6.1111

In patients with chronic bronchitis a four week trial with inhaled steroids does not attenuate airway inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.6.1111

Impaired inhibition by dexamethasone of cytokine release by alveolar macrophages from patients with chronic obstructive pulmonary disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.6.1111

Corticosteroid resistance in airway disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.6.1111

Corticosteroid resistance in chronic obstructive pulmonary disease: inactivation of histone deacetylase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.6.1111

Cysteinyl leukotrienes and 8-isoprostane in exhaled breath condensate of children with asthma exacerbations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.6.1111

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.6.1111

Molecular mechanisms of decreased steroid responsiveness induced by latent adenoviral infection in allergic lung inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.6.1111

Smoking and airway inflammation in patients with mild asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.6.1111

Theophylline: new perspectives for an old drug

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.6.1111

A molecular mechanism of action of theophylline: Induction of histone deacetylase activity to decrease inflammatory gene expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.6.1111

Effect of theophylline on induced sputum inflammatory indices and neutrophil chemotaxis in chronic obstructive pulmonary disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.6.1111

Rational development of histone deacetylase inhibitors as anticancer agents: a review

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.6.1111

Class I histone deacetylase-selective novel synthetic inhibitors potently inhibit human tumor proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.6.1111

Crystal structure of a eukaryotic zinc-dependent histone deacetylase, human HDAC8, complexed with a hydroxamic acid inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.6.1111

PI 3-kinase inhibition: a therapeutic target for respiratory disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.6.1111

Effects of N-acetylcysteine on outcomes in chronic obstructive pulmonary disease (Bronchitis Randomized on NAC Cost-Utility Study, BRONCUS): a randomised placebo-controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.6.1111

Small interfering RNA targeting heme oxygenase-1 enhances ischemia-reperfusion-induced lung apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.6.1111

10.1517/14728222.9.6.1111

21 January 2018

Identifiers

DOI

1 reference

13 August 2017

1 reference

PubMed ID

16300464