(Q36319598)

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Bioenergetics-based modeling of Plasmodium falciparum metabolism reveals its essential genes, nutritional requirements, and thermodynamic bottlenecks.

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28333921%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

Bioenergetics-based modeling of Plasmodium falciparum metabolism reveals its essential genes, nutritional requirements, and thermodynamic bottlenecks (English)

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28333921%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

Plasmodium falciparum

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Anush Chiappino-Pepe

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28333921%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

Stepan Tymoshenko

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28333921%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

3

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13 March 2020

Dominique Soldati-Favre

4

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13 March 2020

Vassily Hatzimanikatis

5

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13 March 2020

author name string

Stepan Tymoshenko

2

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13 August 2017

Meriç Ataman

3

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13 August 2017

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23 March 2017

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13 March 2020

PLOS Computational Biology

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13 March 2020

13

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13 March 2020

3

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13 March 2020

e1005397

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28333921%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

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Creative Commons Attribution 4.0 International

23 March 2017

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Network-based assessment of the selectivity of metabolic drug targets in Plasmodium falciparum with respect to human liver metabolism

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Chronicle of a death foretold: Plasmodium liver stage parasites decide on the fate of the host cell

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Chemical rescue of malaria parasites lacking an apicoplast defines organelle function in blood-stage Plasmodium falciparum

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Purine and pyrimidine pathways as targets in Plasmodium falciparum

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Thermodynamic calculations for biochemical transport and reaction processes in metabolic networks

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Reconstruction and flux-balance analysis of the Plasmodium falciparum metabolic network.

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Antimalarial drug targets in Plasmodium falciparum predicted by stage-specific metabolic network analysis

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The Kennedy phospholipid biosynthesis pathways are refractory to genetic disruption in Plasmodium berghei and therefore appear essential in blood stages

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Network thermodynamics in the post-genomic era.

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What is flux balance analysis?

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New insights into the blood-stage transcriptome of Plasmodium falciparum using RNA-Seq

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A protocol for generating a high-quality genome-scale metabolic reconstruction

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Dihydroorotase from the Hyperthermophile Aquifiex aeolicus Is Activated by Stoichiometric Association with Aspartate Transcarbamoylase and Forms a One-Pot Reactor for Pyrimidine Biosynthesis † ‡

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Metabolite profiling of the intraerythrocytic malaria parasite Plasmodium falciparum by (1)H NMR spectroscopy

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Group contribution method for thermodynamic analysis of complex metabolic networks

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Protein database searches using compositionally adjusted substitution matrices

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The effects of alternate optimal solutions in constraint-based genome-scale metabolic models

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Saccharomyces cerevisiae phenotypes can be predicted by using constraint-based analysis of a genome-scale reconstructed metabolic network

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Systems biology: a brief overview

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1 reference

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Insights gained from P. falciparum cultivation in modified media.

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Substrate channeling.

1 reference

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Metabolic Flux Balancing: Basic Concepts, Scientific and Practical Use

1 reference

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Nutritional requirements of Plasmodium falciparum in culture. III. Further observations on essential nutrients and antimetabolites

1 reference

https://pubmed.ncbi.nlm.nih.gov/28333921

12 December 2020

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inferred from PubMed ID database lookup

Ultrastructural localization of CTP:phosphoethanolamine cytidylyltransferase in rat liver

1 reference

https://pubmed.ncbi.nlm.nih.gov/28333921

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of fosmidomycin on metabolic and transcript profiles of the methylerythritol phosphate pathway in Plasmodium falciparum

1 reference

https://pubmed.ncbi.nlm.nih.gov/28333921

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Culture of Plasmodium falciparum: The Role of pH, Glucose, and Lactate

1 reference

https://pubmed.ncbi.nlm.nih.gov/28333921

12 December 2020

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inferred from PubMed ID database lookup

Oleic acid is indispensable for intraerythrocytic proliferation of Plasmodium falciparum

1 reference

https://pubmed.ncbi.nlm.nih.gov/28333921

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PCBI.1005397

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28333921%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

DBLP publication ID

journals/ploscb/Chiappino-PepeT17

1 reference

DBLP Dataset 2021-01-02

28 January 2021

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28333921%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28333921%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

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