Home
Random
Nearby
Log in
Settings
Donate
About Wikidata
Disclaimers
Search
(Q36321148)
Watch
English
Class II phosphoinositide 3-kinase defines a novel signaling pathway in cell migration.
scientific article
In more languages
edit
Statements
instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PMC publication ID
2171608
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15928202%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 January 2020
title
Class II phosphoinositide 3-kinase defines a novel signaling pathway in cell migration
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
2171608
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15928202%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 January 2020
main subject
cell migration
1 reference
based on heuristic
inferred from title
author
Marco Falasca
series ordinal
6
1 reference
stated in
Europe PubMed Central
PMC publication ID
2171608
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15928202%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 January 2020
author name string
Tania Maffucci
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
2171608
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15928202%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 January 2020
Frank T Cooke
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
2171608
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15928202%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 January 2020
Fiona M Foster
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMC publication ID
2171608
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15928202%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 January 2020
Colin J Traer
series ordinal
4
1 reference
stated in
Europe PubMed Central
PMC publication ID
2171608
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15928202%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 January 2020
Michael J Fry
series ordinal
5
1 reference
stated in
Europe PubMed Central
PMC publication ID
2171608
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15928202%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 January 2020
language of work or name
English
0 references
publication date
31 May 2005
1 reference
stated in
Europe PubMed Central
PMC publication ID
2171608
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15928202%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 January 2020
number of pages
11
1 reference
based on heuristic
inferred from page(s)
published in
Journal of Cell Biology
1 reference
stated in
Europe PubMed Central
PMC publication ID
2171608
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15928202%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 January 2020
volume
169
1 reference
stated in
Europe PubMed Central
PMC publication ID
2171608
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15928202%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 January 2020
issue
5
1 reference
stated in
Europe PubMed Central
PMC publication ID
2171608
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15928202%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 January 2020
page(s)
789-799
1 reference
stated in
Europe PubMed Central
PMC publication ID
2171608
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15928202%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 January 2020
cites work
G protein mediated signaling pathways in lysophospholipid induced cell proliferation and survival
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2171608
retrieved
30 September 2017
Activation of p21-activated kinase 1 is required for lysophosphatidic acid-induced focal adhesion kinase phosphorylation and cell motility in human melanoma A2058 cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2171608
retrieved
30 September 2017
Inositol pentakisphosphate promotes apoptosis through the PI 3-K/Akt pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2171608
retrieved
30 September 2017
Lysophosphatidic acid and autotaxin stimulate cell motility of neoplastic and non-neoplastic cells through LPA1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2171608
retrieved
30 September 2017
LPA: a novel lipid mediator with diverse biological actions
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2171608
retrieved
30 September 2017
Lysophosphatidic acid (LPA) in malignant ascites stimulates motility of human pancreatic cancer cells through LPA1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2171608
retrieved
30 September 2017
Lysophosphatidic acid: mitogen and motility factor
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2171608
retrieved
30 September 2017
Expression of myotubularin by an adenoviral vector demonstrates its function as a phosphatidylinositol 3-phosphate [PtdIns(3)P] phosphatase in muscle cell lines: involvement of PtdIns(3)P in insulin-stimulated glucose transport
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2171608
retrieved
30 September 2017
Insulin induces phosphatidylinositol-3-phosphate formation through TC10 activation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2171608
retrieved
30 September 2017
The emerging role of lysophosphatidic acid in cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2171608
retrieved
30 September 2017
The phosphoinositide (PI) 3-kinase family
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2171608
retrieved
30 September 2017
TACE cleavage of proamphiregulin regulates GPCR-induced proliferation and motility of cancer cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2171608
retrieved
30 September 2017
Two distinct phosphoinositide 3-kinases mediate polypeptide growth factor-stimulated PKB activation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2171608
retrieved
30 September 2017
Autotaxin has lysophospholipase D activity leading to tumor cell growth and motility by lysophosphatidic acid production
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2171608
retrieved
30 September 2017
The PtdIns3P phosphatase myotubularin is a cytoplasmic protein that also localizes to Rac1-inducible plasma membrane ruffles
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2171608
retrieved
30 September 2017
Lysophospholipids and their G protein-coupled receptors in inflammation and immunity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2171608
retrieved
30 September 2017
Phosphoinositide 3-kinases in lysophosphatidic acid signaling: regulation and cross-talk with the Ras/mitogen-activated protein kinase pathway.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2171608
retrieved
30 September 2017
Analysis of gene function in somatic mammalian cells using small interfering RNAs
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2171608
retrieved
30 September 2017
The phosphoinositide 3-kinase pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2171608
retrieved
30 September 2017
Positional effects of short interfering RNAs targeting the human coagulation trigger Tissue Factor
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2171608
retrieved
30 September 2017
ZD1839 (Iressa), a novel epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor, potently inhibits the growth of EGFR-positive cancer cell lines with or without erbB2 overexpression
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2171608
retrieved
30 September 2017
Cellular function of phosphoinositide 3-kinases: implications for development, homeostasis, and cancer.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2171608
retrieved
30 September 2017
Growth factor regulation of the novel class II phosphoinositide 3-kinases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2171608
retrieved
30 September 2017
The class II phosphoinositide 3-kinase C2alpha is activated by clathrin and regulates clathrin-mediated membrane trafficking
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2171608
retrieved
30 September 2017
Expression of the BRK tyrosine kinase in mammary epithelial cells enhances the coupling of EGF signalling to PI 3-kinase and Akt, via erbB3 phosphorylation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2171608
retrieved
30 September 2017
Localization of phosphatidylinositol 3-phosphate in yeast and mammalian cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2171608
retrieved
30 September 2017
Class II phosphoinositide 3-kinases are downstream targets of activated polypeptide growth factor receptors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2171608
retrieved
30 September 2017
An epidermal growth factor receptor/Gab1 signaling pathway is required for activation of phosphoinositide 3-kinase by lysophosphatidic acid.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2171608
retrieved
30 September 2017
Insulin activates the alpha isoform of class II phosphoinositide 3-kinase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2171608
retrieved
30 September 2017
The role of phosphoinositide 3-kinase lipid products in cell function
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2171608
retrieved
30 September 2017
Human phosphoinositide 3-kinase C2beta, the role of calcium and the C2 domain in enzyme activity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2171608
retrieved
30 September 2017
The CC chemokine monocyte chemotactic peptide-1 activates both the class I p85/p110 phosphatidylinositol 3-kinase and the class II PI3K-C2alpha.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2171608
retrieved
30 September 2017
Malignant effusions contain lysophosphatidic acid (LPA)-like activity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2171608
retrieved
30 September 2017
A type II phosphoinositide 3-kinase is stimulated via activated integrin in platelets. A source of phosphatidylinositol 3-phosphate
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2171608
retrieved
30 September 2017
The G beta gamma sensitivity of a PI3K is dependent upon a tightly associated adaptor, p101
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2171608
retrieved
30 September 2017
The role of the pleckstrin homology domain in membrane targeting and activation of phospholipase Cbeta(1).
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2171608
retrieved
29 June 2018
PI 3-kinase gamma and protein kinase C-zeta mediate RAS-independent activation of MAP kinase by a Gi protein-coupled receptor
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2171608
retrieved
29 June 2018
Lysophosphatidic Acid Stimulates Ovarian Cancer Cell Migration via a Ras-MEK Kinase 1 Pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2171608
retrieved
22 September 2018
Mechanisms in LPA-induced tumor cell migration: critical role of phosphorylated ERK.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2171608
retrieved
22 September 2018
Specific inhibition of AQP1 water channels in isolated rat intrahepatic bile duct units by small interfering RNAs
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2171608
retrieved
22 September 2018
Role for 18:1 lysophosphatidic acid as an autocrine mediator in prostate cancer cells
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/15928202
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Characterization of an ovarian cancer activating factor in ascites from ovarian cancer patients
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/15928202
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1083/JCB.200408005
1 reference
stated in
Europe PubMed Central
PMC publication ID
2171608
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15928202%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 January 2020
PMC publication ID
2171608
1 reference
stated in
Europe PubMed Central
PMC publication ID
2171608
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15928202%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 January 2020
PubMed publication ID
15928202
1 reference
stated in
Europe PubMed Central
PMC publication ID
2171608
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15928202%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 January 2020
ResearchGate publication ID
7814249
0 references
Sitelinks
Wikipedia
(0 entries)
edit
Wikibooks
(0 entries)
edit
Wikinews
(0 entries)
edit
Wikiquote
(0 entries)
edit
Wikisource
(0 entries)
edit
Wikiversity
(0 entries)
edit
Wikivoyage
(0 entries)
edit
Wiktionary
(0 entries)
edit
Multilingual sites
(0 entries)
edit