(Q36323412)

13 August 2017

Monoclonal antibodies to the human insulin receptor block insulin binding and inhibit insulin action (English)

1 reference

13 August 2017

1 reference

1 reference

1 reference

R. A. Roth

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A6185950

23 August 2023

D. J. Cassell

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A6185950

23 August 2023

K. Y. Wong

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A6185950

23 August 2023

B. A. Maddux

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A6185950

23 August 2023

I. D. Goldfine

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A6185950

23 August 2023

language of work or name

English

0 references

publication date

1 December 1982

1 reference

13 August 2017

5

1 reference

full work available at URL

inferred from page(s)

https://europepmc.org/articles/PMC347329

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A6185950

https://europepmc.org/articles/PMC347329?pdf=render

23 August 2023

file format

Portable Document Format

online access status

open access

content deliverer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A6185950

https://pnas.org/doi/pdf/10.1073/pnas.79.23.7312

23 August 2023

1 reference

Crossref

DOI

10.1073/PNAS.79.23.7312

https://api.crossref.org/works/10.1073/PNAS.79.23.7312

Proceedings of the National Academy of Sciences of the United States of America

23 August 2023

published in

1 reference

13 August 2017

79

1 reference

13 August 2017

7312-7316

1 reference

13 August 2017

23

1 reference

Production of monoclonal antibodies: strategy and tactics

13 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=347329

Biosynthetic labeling of insulin receptor: studies of subunits in cultured human IM-9 lymphocytes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=347329

Electrophoretic resolution of three major insulin receptor structures with unique subunit stoichiometries

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=347329

Insulin receptor: structure and function

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=347329

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=347329

Direct method for detection and characterization of cell surface receptors for insulin by means of 125I-labeled autoantibodies against the insulin receptor

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=347329

Effects of autoantibodies to the insulin receptor on isolated adipocytes. Studies of insulin binding and insulin action

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=347329

Insulin receptor: covalent labeling and identification of subunits

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=347329

Direct demonstration that receptor crosslinking or aggregation is important in insulin action

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=347329

Binding of insulin to isolated nuclei

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=347329

Action of insulin analogues on cultured human fibroblasts reflects biological potency

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=347329

Antibodies That Impair Insulin Receptor Binding in an Unusual Diabetic Syndrome with Severe Insulin Resistance

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=347329

Specificities of rabbit anti-human insulin receptor antibodies

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=347329

The Insulin Receptor in Vertebrates Is Functionally More Conserved during Evolution than Insulin Itself

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=347329

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=347329

Photoaffinity labeling of insulin receptor proteins of liver plasma membrane preparations

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=347329

Purification and properties of the human placental insulin receptor.

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=347329

Binding and degradation of 125I-labelled insulin by isolated rat fat cells

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=347329

Characteristics of the human lymphocyte insulin receptor

22 September 2018

1 reference

12 December 2020

Purification and properties of insulin receptors from rat liver membranes

1 reference

12 December 2020

Antibodies to purified insulin receptor have insulin-like activity

1 reference

12 December 2020

The Role of Insulin Receptors and Receptor Antibodies in States of Altered Insulin Action

1 reference

12 December 2020

The subunit structure of the high affinity insulin receptor. Evidence for a disulfide-linked receptor complex in fat cell and liver plasma membranes

1 reference

12 December 2020

Characterization of insulin-like actions of anti-insulin receptor antibodies. Effects on insulin binding, insulin degradation, and glycogen synthesis in isolated rat hepatocytes

1 reference

12 December 2020

The subunit structure of rat liver insulin receptor. Antibodies directed against the insulin-binding subunit

1 reference

12 December 2020

Purification of the insulin receptor from human placenta by chromatography on immobilized wheat germ lectin and receptor antibody

1 reference

12 December 2020

Demonstration of two subtypes of insulin-like growth factor receptors by affinity cross-linking

1 reference

12 December 2020

Production of antibodies that inhibit the binding of insulin to its receptor

1 reference

12 December 2020

Insulin-like stimulatory effect of human immunoglobulin G on adipocyte lipogenesis

1 reference

12 December 2020

Structure of the insulin receptor of the cultured human lymphoblastoid cell IM-9. Evidence suggesting that two subunits are required for insulin binding

1 reference

12 December 2020

The subunit structures of two distinct receptors for insulin-like growth factors I and II and their relationship to the insulin receptor

1 reference

12 December 2020

Stimulatory effects of prolactin and anti-prolactin receptor serum on prolactin binding sites in rat liver cells in suspension culture.

1 reference

12 December 2020

A monoclonal antibody to human insulin receptor

1 reference

12 December 2020

METABOLISM OF ISOLATED FAT CELLS. I. EFFECTS OF HORMONES ON GLUCOSE METABOLISM AND LIPOLYSIS

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.79.23.7312

1 reference

13 August 2017

0 references

1 reference

13 August 2017

1 reference

PMCID

347329