(Q36328456)

13 August 2017

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title

The robotic mouse: unravelling the function of AF4 in the cerebellum (English)

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13 August 2017

Emmanuelle Bitoun

1

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PubMed ID

16321881

13 August 2017

Kay Elizabeth Davies

series ordinal

2

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13 August 2017

1 January 2005

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13 August 2017

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13 August 2017

4

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13 August 2017

250-260

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13 August 2017

4

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https://scigraph.springernature.com/pub.10.1080/14734220500325897

13 August 2017

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cites work

Cooperativity in transcription factor binding to the coactivator CREB-binding protein (CBP). The mixed lineage leukemia protein (MLL) activation domain binds to an allosteric site on the KIX domain

1 reference

12 December 2020

Large-scale mutagenesis of the mouse to understand the genetic bases of nervous system structure and function

1 reference

12 December 2020

Mouse Af9 is a controller of embryo patterning, like Mll, whose human homologue fuses with Af9 after chromosomal translocation in leukemia

1 reference

12 December 2020

Aberrant protein deposition and neurological disease

1 reference

12 December 2020

Identification of a novel RAS GTPase-activating protein (RASGAP) gene at 9q34 as an MLL fusion partner in a patient with de novo acute myeloid leukemia

1 reference

12 December 2020

cDNA cloning, expression and chromosomal localization of the murine AF-4 gene involved in human leukemia

1 reference

12 December 2020

Cloning of murine CDK9/PITALRE and its tissue-specific expression in development

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12 December 2020

Cyclic-AMP-responsive transcriptional activation of CREB-327 involves interdependent phosphorylated subdomains

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12 December 2020

EPS8 and E3B1 transduce signals from Ras to Rac

1 reference

12 December 2020

The amygdala and emotion

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12 December 2020

A binding motif for Siah ubiquitin ligase.

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12 December 2020

SYT associates with human SNF/SWI complexes and the C-terminal region of its fusion partner SSX1 targets histones

1 reference

12 December 2020

EAF1, a novel ELL-associated factor that is delocalized by expression of the MLL-ELL fusion protein

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12 December 2020

Cerebellar contributions to cognition

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12 December 2020

The structure of the human ALL-1/MLL/HRX gene.

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12 December 2020

Expression of the murine homologue of FMR2 in mouse brain and during development

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12 December 2020

Genomic structure of the POU-related hepatic transcription factor HNF-1 alpha.

1 reference

12 December 2020

Involvement of a homolog of Drosophila trithorax by 11q23 chromosomal translocations in acute leukemias

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12 December 2020

Novel SWI/SNF chromatin-remodeling complexes contain a mixed-lineage leukemia chromosomal translocation partner

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12 December 2020

New aspects of the pathology of neurodegenerative disorders as revealed by ubiquitin antibodies

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12 December 2020

A systematic, genome-wide, phenotype-driven mutagenesis programme for gene function studies in the mouse

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12 December 2020

Purkinje cell degeneration, a new neurological mutation in the mouse

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12 December 2020

The compartmentalization of the cerebellum

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12 December 2020

LAF-4 encodes a lymphoid nuclear protein with transactivation potential that is homologous to AF-4, the gene fused to MLL in t(4;11) leukemias

1 reference

12 December 2020

The interaction between EEN and Abi-1, two MLL fusion partners, and synaptojanin and dynamin: implications for leukaemogenesis

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12 December 2020

Subnuclear organization and trafficking of regulatory proteins: implications for biological control and cancer.

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12 December 2020

Cerebellar cell degeneration in the leaner mutant mouse.

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12 December 2020

Cloning and developmental expression of the murine homolog of the acute leukemia proto-oncogene AF4

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12 December 2020

Mediation of Af4 protein function in the cerebellum by Siah proteins

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12 December 2020

The mouse Laf4 gene: exon/intron organization, cDNA sequence, alternative splicing, and expression during central nervous system development.

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12 December 2020

Molecular cloning of 19p13 breakpoint region in infantile leukemia with t(11;19)(q23;p13) translocation

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12 December 2020

Regulation of a Purkinje cell-specific promoter by homeodomain proteins: repression by engrailed-2 vs. synergistic activation by Hoxa5 and Hoxb7.

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12 December 2020

Purkinje cell degeneration (pcd) phenotypes caused by mutations in the axotomy-induced gene, Nna1

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12 December 2020

Aggresomes formed by alpha-synuclein and synphilin-1 are cytoprotective

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12 December 2020

Ultrastructural changes in the mitochondria of cerebellar Purkinje cells of nervous mutant mice

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12 December 2020

Target neuron controls the integrity of afferent axon phenotype: a study on the Purkinje cell-climbing fiber system in cerebellar mutant mice

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12 December 2020

The role of HOX homeobox genes in normal and leukemic hematopoiesis

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12 December 2020

Exon/intron structure of the human AF-4 gene, a member of the AF-4/LAF-4/FMR-2 gene family coding for a nuclear protein with structural alterations in acute leukaemia

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12 December 2020

Purkinje cell loss from alternating sagittal zones in the cerebellum of leaner mutant mice

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12 December 2020

Identification and characterization of EBP, a novel EEN binding protein that inhibits Ras signaling and is recruited into the nucleus by the MLL-EEN fusion protein

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12 December 2020

P-TEFb, a cyclin-dependent kinase controlling elongation by RNA polymerase II

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12 December 2020

Mouse mutagenesis-systematic studies of mammalian gene function

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12 December 2020

Mnemonic theories of hippocampal function

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12 December 2020

Structure and function of transcriptional activation domains

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12 December 2020

The murine SNF5/INI1 chromatin remodeling factor is essential for embryonic development and tumor suppression

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12 December 2020

Identification of the gene FMR2, associated with FRAXE mental retardation

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12 December 2020

Factors associated with the mammalian RNA polymerase II holoenzyme

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12 December 2020

Acid sphingomyelinase deficient mice: a model of types A and B Niemann-Pick disease

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12 December 2020

The C-terminal SET domains of ALL-1 and TRITHORAX interact with the INI1 and SNR1 proteins, components of the SWI/SNF complex

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12 December 2020

Ubiquitinated inclusions and neuronal cell death

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12 December 2020

Patterned cerebellar Purkinje cell death in a transgenic mouse model of Niemann Pick type A/B disease

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12 December 2020

Chimeric MLL products with a Ras binding cytoplasmic protein AF6 involved in t(6;11) (q27;q23) leukemia localize in the nucleus

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12 December 2020

Common developmental genetic mechanisms for patterning invertebrate and vertebrate brains

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12 December 2020

AF5q31, a newly identified AF4-related gene, is fused to MLL in infant acute lymphoblastic leukemia with ins(5;11)(q31;q13q23)

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12 December 2020

Activation and repression in the nervous system.

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12 December 2020

ENL, the gene fused with HRX in t(11;19) leukemias, encodes a nuclear protein with transcriptional activation potential in lymphoid and myeloid cells

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12 December 2020

ELL-associated factor 2 (EAF2), a functional homolog of EAF1 with alternative ELL binding properties

1 reference

12 December 2020

Reproductive pathology and sperm physiology in acid sphingomyelinase-deficient mice

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12 December 2020

The polycomb protein MPc3 interacts with AF9, an MLL fusion partner in t(9;11)(p22;q23) acute leukemias

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12 December 2020

AF4 encodes a ubiquitous protein that in both native and MLL-AF4 fusion types localizes to subnuclear compartments

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12 December 2020

Domains with transcriptional regulatory activity within the ALL1 and AF4 proteins involved in acute leukemia

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12 December 2020

A mutation in Af4 is predicted to cause cerebellar ataxia and cataracts in the robotic mouse.

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12 December 2020

The t(4;11) chromosome translocation of human acute leukemias fuses the ALL-1 gene, related to Drosophila trithorax, to the AF-4 gene

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12 December 2020

ELL2, a new member of an ELL family of RNA polymerase II elongation factors

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12 December 2020

A novel dynamin-associating molecule, formin-binding protein 17, induces tubular membrane invaginations and participates in endocytosis

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12 December 2020

Seven in absentia homolog 1A mediates ubiquitination and degradation of group 1 metabotropic glutamate receptors

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12 December 2020

Rostrocaudal expression of antibody HNK-1-reactive glycolipids in mouse cerebellum: relationship to developmental compartments and leaner mutation.

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12 December 2020

Mutant mice as a model for cerebellar ataxia

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12 December 2020

Leukemic HRX fusion proteins inhibit GADD34-induced apoptosis and associate with the GADD34 and hSNF5/INI1 proteins

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12 December 2020

An RNA polymerase II elongation factor encoded by the human ELL gene

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12 December 2020

Mammalian Trithorax and polycomb-group homologues are antagonistic regulators of homeotic development

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12 December 2020

SIAH1 targets the alternative splicing factor T-STAR for degradation by the proteasome

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12 December 2020

The mixed lineage leukemia fusion partner AF9 binds specific isoforms of the BCL-6 corepressor

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12 December 2020

The MLL fusion partner AF10 binds GAS41, a protein that interacts with the human SWI/SNF complex

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12 December 2020

The ENL moiety of the childhood leukemia-associated MLL-ENL oncoprotein recruits human Polycomb 3

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12 December 2020

SWI/SNF chromatin remodeling and cancer

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12 December 2020

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12 December 2020

p300 interacts with the nuclear proto-oncoprotein SYT as part of the active control of cell adhesion

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12 December 2020

Transcriptional activation. Switched-on chromatin

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12 December 2020

Constitutive expression of heat shock protein HSP25 in the central nervous system of the developing and adult mouse.

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12 December 2020

The leukemia-associated gene Mllt1/ENL: characterization of a murine homolog and demonstration of an essential role in embryonic development.

1 reference

12 December 2020

Identification of a novel SNF2/SWI2 protein family member, SRCAP, which interacts with CREB-binding protein

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12 December 2020

MLL fusion partners AF4 and AF9 interact at subnuclear foci

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12 December 2020

MCEF, the newest member of the AF4 family of transcription factors involved in leukemia, is a positive transcription elongation factor-b-associated protein

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12 December 2020

PHYL acts to down-regulate TTK88, a transcriptional repressor of neuronal cell fates, by a SINA-dependent mechanism.

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12 December 2020

MLLT3 gene on 9p22 involved in t(9;11) leukemia encodes a serine/proline rich protein homologous to MLLT1 on 19p13.

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12 December 2020

Gene structure and subcellular localization of FMR2, a member of a new family of putative transcription activators

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12 December 2020

Chromatin remodeling in development and differentiation.

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12 December 2020

Fragile XE-associated familial mental retardation protein 2 (FMR2) acts as a potent transcription activator

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12 December 2020

Altered Hox expression and segmental identity in Mll-mutant mice

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12 December 2020

A relationship between cerebellar Purkinje cells and spatial working memory demonstrated in a lurcher/chimera mouse model system

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12 December 2020

BCoR, a novel corepressor involved in BCL-6 repression

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12 December 2020

Impaired conditioned fear and enhanced long-term potentiation in Fmr2 knock-out mice

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12 December 2020

Trinucleotide repeat amplification and hypermethylation of a CpG island in FRAXE mental retardation.

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12 December 2020

ENL, the MLL fusion partner in t(11;19), binds to the c-Abl interactor protein 1 (ABI1) that is fused to MLL in t(10;11)+.

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12 December 2020

Synaptojanin 1: localization on coated endocytic intermediates in nerve terminals and interaction of its 170 kDa isoform with Eps15

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12 December 2020

Isolation of 10 differentially expressed cDNAs in p53-induced apoptosis: activation of the vertebrate homologue of the drosophila seven in absentia gene

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12 December 2020

Altered lymphoid development in mice deficient for the mAF4 proto-oncogene

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12 December 2020

The synovial sarcoma associated protein SYT interacts with the acute leukemia associated protein AF10

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12 December 2020

Cerebellar mutations affecting the postnatal survival of Purkinje cells in the mouse disclose a longitudinal pattern of differentially sensitive cells.

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12 December 2020

Absence epilepsy in tottering mutant mice is associated with calcium channel defects

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12 December 2020

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12 December 2020

Cellular and molecular control of dendritic growth and development of cerebellar Purkinje cells

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12 December 2020

DNA fragmentation and activation of c-Jun in the cerebellum of mutant mice (weaver, Purkinje cell degeneration).

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12 December 2020

Localization of the fragile X mental retardation 2 (FMR2) protein in mammalian brain.

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12 December 2020

Sox-4, an Sry-like HMG box protein, is a transcriptional activator in lymphocytes

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12 December 2020

10.1080/14734220500325897

Identifiers

DOI

1 reference

PubMed ID

16321881

Dimensions Publication ID

13 August 2017

0 references

1 reference

PubMed ID

16321881