(Q36330247)

English

Human liver microsomal metabolism of the enantiomers of warfarin and acenocoumarol: P450 isozyme diversity determines the differences in their pharmacokinetics

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Human liver microsomal metabolism of the enantiomers of warfarin and acenocoumarol: P450 isozyme diversity determines the differences in their pharmacokinetics (English)

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

pharmacokinetics

1 reference

based on heuristic

inferred from title

author name string

Hermans JJ

1

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Thijssen HH

2

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

language of work or name

0 references

publication date

1 September 1993

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

British Journal of Pharmacology

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

110

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

1

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

482-490

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Protein measurement with the Folin phenol reagent

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2175972

30 September 2017

Purification and characterization of microsomal cytochrome P-450s

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2175972

30 September 2017

Warfarin. Stereochemical aspects of its metabolism and the interaction with phenylbutazone

1 reference

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30 September 2017

Clinical pharmacokinetics and pharmacodynamics of warfarin. Understanding the dose-effect relationship.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2175972

30 September 2017

Warfarin as a probe of cytochromes P-450 function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2175972

30 September 2017

The P450 superfamily: update on new sequences, gene mapping, and recommended nomenclature

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2175972

30 September 2017

Omeprazole drug interaction studies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2175972

30 September 2017

Characterization of human cytochrome P450 enzymes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2175972

30 September 2017

A study of the interaction of omeprazole and warfarin in anticoagulated patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2175972

30 September 2017

Clinical Pharmacokinetics of Oral Anticoagulants

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2175972

30 September 2017

Enantiomers of warfarin and vitamin K1 metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2175972

29 June 2018

Inhibition of human liver cytochrome P-450 by omeprazole

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2175972

29 June 2018

Cimetidine-nicoumalone interaction in man: stereochemical considerations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2175972

29 June 2018

Tolbutamide and mephenytoin hydroxylation by human cytochrome P450s in the CYP2C subfamily

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2175972

29 June 2018

Enantioselective structure-pharmacokinetic relationships of ring substituted warfarin analogues in the rat.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2175972

29 June 2018

Further insight into the stereoselective interaction between warfarin and cimetidine in man

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2175972

29 June 2018

Hydroxylation of warfarin by human cDNA-expressed cytochrome P-450: a role for P-4502C9 in the etiology of (S)-warfarin-drug interactions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2175972

29 June 2018

Disposition kinetics and metabolism of omeprazole in extensive and poor metabolizers of S-mephenytoin 4'-hydroxylation recruited from an Oriental population.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2175972

29 June 2018

An improved assay of 7-ethoxycoumarin O-deethylase activity: induction of hepatic enzyme activity in C57BL/6J and DBA/2J mice by phenobarbital, 3-methylcholanthrene and 2,3,7,8-tetrachlorodibenzo-p-dioxin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2175972

29 June 2018

Stereoselective aspects in the pharmacokinetics and pharmacodynamics of acenocoumarol and its amino and acetamido derivatives in the rat.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2175972

22 September 2018

In vitro characterization of the human cytochrome P-450 involved in polymorphic oxidation of propafenone

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.1993.TB13836.X

21 January 2018

Identification and characterization of the cytochrome P450 enzymes involved in N-dealkylation of propafenone: molecular base for interaction potential and variable disposition of active metabolites

1 reference

https://pubmed.ncbi.nlm.nih.gov/8220911

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Post mortem characteristics of the hepatic microsomal drug oxidising enzyme system

1 reference

https://pubmed.ncbi.nlm.nih.gov/8220911

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stereoselective interaction of trimethoprim-sulfamethoxazole with the separated enantiomorphs of racemic warfarin in man

1 reference

https://pubmed.ncbi.nlm.nih.gov/8220911

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Purification and characterization of six cytochrome P-450 isozymes from human liver microsomes

1 reference

https://pubmed.ncbi.nlm.nih.gov/8220911

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of monooxygenase activities and cytochrome P-450 isozyme concentrations in human liver microsomes

1 reference

https://pubmed.ncbi.nlm.nih.gov/8220911

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lack of effect of cimetidine on pharmacodynamics and kinetics of single oral doses of R- and S-acenocoumarol

1 reference

https://pubmed.ncbi.nlm.nih.gov/8220911

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enoxacin-warfarin interaction: pharmacokinetic and stereochemical aspects

1 reference

https://pubmed.ncbi.nlm.nih.gov/8220911

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interaction of amiodarone with racemic warfarin and its separated enantiomorphs in humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/8220911

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interaction between warfarin and propafenone in healthy volunteer subjects

1 reference

https://pubmed.ncbi.nlm.nih.gov/8220911

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

4-Hydroxycoumarin oral anticoagulants: pharmacokinetics-response relationship

1 reference

https://pubmed.ncbi.nlm.nih.gov/8220911

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stereoselective interaction of omeprazole with warfarin in healthy men

1 reference

https://pubmed.ncbi.nlm.nih.gov/8220911

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characteristics of warfarin hydroxylation catalyzed by human liver microsomes

1 reference

https://pubmed.ncbi.nlm.nih.gov/8220911

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The in vitro ketone reduction of warfarin and analogues. Substrate stereoselectivity, product stereoselectivity and species differences

1 reference

https://pubmed.ncbi.nlm.nih.gov/8220911

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Separation of human liver microsomal tolbutamide hydroxylase and (S)-mephenytoin 4'-hydroxylase cytochrome P-450 enzymes

1 reference

https://pubmed.ncbi.nlm.nih.gov/8220911

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of the rat liver microsomal metabolism of the enantiomers of warfarin and 4′-nitrowarfarin (Acenocoumarol)

1 reference

https://pubmed.ncbi.nlm.nih.gov/8220911

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Properties and stereoselectivity of carbonyl reductases involved in the ketone reduction of warfarin and analogues

1 reference

https://pubmed.ncbi.nlm.nih.gov/8220911

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1111/J.1476-5381.1993.TB13836.X

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

ResearchGate publication ID

0 references

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