(Q36331308)

13 August 2017

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title

The role of vesicular transport in ABCA1-dependent lipid efflux and its connection with NPC pathways (English)

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13 August 2017

Emmanuel Boadu

1

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13 August 2017

Gordon A Francis

series ordinal

2

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13 August 2017

publication date

17 November 2005

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Journal of Molecular Medicine

13 August 2017

published in

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13 August 2017

volume

84

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13 August 2017

issue

4

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13 August 2017

page(s)

266-275

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Type C Niemann-Pick disease: spectrum of phenotypic variation in disruption of intracellular LDL-derived cholesterol processing

13 August 2017

cites work

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12 December 2020

ADP-ribosylation factor (ARF)-like 7 (ARL7) is induced by cholesterol loading and participates in apolipoprotein AI-dependent cholesterol export

1 reference

12 December 2020

The ABCA1 transporter modulates late endocytic trafficking: insights from the correction of the genetic defect in Tangier disease

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12 December 2020

ABCA1 is the cAMP-inducible apolipoprotein receptor that mediates cholesterol secretion from macrophages

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12 December 2020

ABCA1-mediated cholesterol efflux is defective in free cholesterol-loaded macrophages. Mechanism involves enhanced ABCA1 degradation in a process requiring full NPC1 activity

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12 December 2020

Apolipoprotein specificity for lipid efflux by the human ABCAI transporter

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12 December 2020

Naturally occurring mutations in the largest extracellular loops of ABCA1 can disrupt its direct interaction with apolipoprotein A-I

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12 December 2020

The human ATP-binding cassette (ABC) transporter superfamily.

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12 December 2020

Differential accumulation of cholesterol in Golgi compartments of normal and Niemann-Pick type C fibroblasts incubated with LDL: a cytochemical freeze-fracture study

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12 December 2020

Transport of lipids from golgi to plasma membrane is defective in tangier disease patients and Abc1-deficient mice

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12 December 2020

Intracellular cholesterol transport

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12 December 2020

ABCA1 mRNA and protein distribution patterns predict multiple different roles and levels of regulation

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12 December 2020

The gene encoding ATP-binding cassette transporter 1 is mutated in Tangier disease

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12 December 2020

Cellular localization and trafficking of the human ABCA1 transporter

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12 December 2020

Molecular and cellular physiology of apolipoprotein A-I lipidation by the ATP-binding cassette transporter A1 (ABCA1).

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12 December 2020

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12 December 2020

Niemann-Pick C1 Like 1 protein is critical for intestinal cholesterol absorption

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12 December 2020

The RND permease superfamily: an ancient, ubiquitous and diverse family that includes human disease and development proteins.

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12 December 2020

Differential trafficking of the Niemann-Pick C1 and 2 proteins highlights distinct roles in late endocytic lipid trafficking.

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12 December 2020

Binding between the Niemann-Pick C1 protein and a photoactivatable cholesterol analog requires a functional sterol-sensing domain

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12 December 2020

Niemann-Pick C1 is a late endosome-resident protein that transiently associates with lysosomes and the trans-Golgi network

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12 December 2020

ATP-binding cassette transporter A7 (ABCA7) binds apolipoprotein A-I and mediates cellular phospholipid but not cholesterol efflux

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12 December 2020

Helical apolipoproteins stabilize ATP-binding cassette transporter A1 by protecting it from thiol protease-mediated degradation

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12 December 2020

Low density lipoprotein (LDL)-mediated suppression of cholesterol synthesis and LDL uptake is defective in Niemann-Pick type C fibroblasts

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12 December 2020

Molecular cloning of the human ATP-binding cassette transporter 1 (hABC1): evidence for sterol-dependent regulation in macrophages.

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12 December 2020

The Niemann-Pick C lesion and its relationship to the intracellular distribution and utilization of LDL cholesterol

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12 December 2020

Mutations in ABC1 in Tangier disease and familial high-density lipoprotein deficiency

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12 December 2020

Human ABCA7 supports apolipoprotein-mediated release of cellular cholesterol and phospholipid to generate high density lipoprotein

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12 December 2020

ATP-binding cassette transporter A1 contains an NH2-terminal signal anchor sequence that translocates the protein's first hydrophilic domain to the exoplasmic space.

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12 December 2020

Apolipoprotein-mediated removal of cellular cholesterol and phospholipids

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12 December 2020

Tangier disease is caused by mutations in the gene encoding ATP-binding cassette transporter 1

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12 December 2020

The Niemann-Pick C1 protein resides in a vesicular compartment linked to retrograde transport of multiple lysosomal cargo

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12 December 2020

Disruption of the acyl-CoA:cholesterol acyltransferase gene in mice: evidence suggesting multiple cholesterol esterification enzymes in mammals

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12 December 2020

Niemann-Pick C1 disease gene: homology to mediators of cholesterol homeostasis

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12 December 2020

Relevance of Niemann-Pick type C1 protein expression in controlling plasma cholesterol and biliary lipid secretion in mice

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12 December 2020

Janus kinase 2 modulates the apolipoprotein interactions with ABCA1 required for removing cellular cholesterol

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12 December 2020

Niemann-Pick type C disease: importance of N-glycosylation sites for function and cellular location of the NPC2 protein

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12 December 2020

Defective removal of cellular cholesterol and phospholipids by apolipoprotein A-I in Tangier Disease

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12 December 2020

Identification of HE1 as the second gene of Niemann-Pick C disease

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12 December 2020

Sterol-dependent transactivation of the ABC1 promoter by the liver X receptor/retinoid X receptor

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12 December 2020

Localization of human ATP-binding cassette transporter 1 (ABC1) in normal and atherosclerotic tissues

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12 December 2020

A PEST deletion mutant of ABCA1 shows impaired internalization and defective cholesterol efflux from late endosomes

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12 December 2020

Sterol-modulated glycolipid sorting occurs in niemann-pick C1 late endosomes

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12 December 2020

Mobilization of late-endosomal cholesterol is inhibited by Rab guanine nucleotide dissociation inhibitor

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12 December 2020

Cloning of two novel ABC transporters mapping on human chromosome 9

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12 December 2020

A PEST sequence in ABCA1 regulates degradation by calpain protease and stabilization of ABCA1 by apoA-I.

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12 December 2020

The high density lipoprotein- and apolipoprotein A-I-induced mobilization of cellular cholesterol is impaired in fibroblasts from Tangier disease subjects

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12 December 2020

Phosphorylation by protein kinase CK2 modulates the activity of the ATP binding cassette A1 transporter

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12 December 2020

A defect in cholesterol esterification in Niemann-Pick disease (type C) patients

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12 December 2020

Intracellular cholesterol trafficking: role of the NPC1 protein

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12 December 2020

ATP-binding cassette transporter A1 and cholesterol trafficking

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12 December 2020

Regulation and intracellular trafficking of the ABCA1 transporter

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12 December 2020

Specific binding of ApoA-I, enhanced cholesterol efflux, and altered plasma membrane morphology in cells expressing ABC1.

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12 December 2020

Cholesterol movement in Niemann-Pick type C cells and in cells treated with amphiphiles

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12 December 2020

The endoplasmic reticulum is the site of cholesterol-induced cytotoxicity in macrophages

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12 December 2020

Impaired ABCA1-dependent lipid efflux and hypoalphalipoproteinemia in human Niemann-Pick type C disease

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12 December 2020

The structure and function of the Niemann-Pick C1 protein

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12 December 2020

Sterols and intracellular vesicular trafficking: lessons from the study of NPC1.

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12 December 2020

Evaluation of the role of phosphatidylserine translocase activity in ABCA1-mediated lipid efflux

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12 December 2020

Molecular cloning and characterization of HE1, a major secretory protein of the human epididymis

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12 December 2020

Cholesterol trafficking in the secretory and endocytic systems

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12 December 2020

Decreased reverse cholesterol transport from Tangier disease fibroblasts. Acceptor specificity and effect of brefeldin on lipid efflux

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12 December 2020

Age and residual cholesterol efflux affect HDL cholesterol levels and coronary artery disease in ABCA1 heterozygotes.

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12 December 2020

Secretory vesicular transport from the Golgi is altered during ATP-binding cassette protein A1 (ABCA1)-mediated cholesterol efflux

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12 December 2020

Phosphorylation of a pest sequence in ABCA1 promotes calpain degradation and is reversed by ApoA-I

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12 December 2020

Genetic evidence for nonredundant functional cooperativity between NPC1 and NPC2 in lipid transport

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12 December 2020

Preferential ATP-binding cassette transporter A1-mediated cholesterol efflux from late endosomes/lysosomes

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12 December 2020

cAMP induces ABCA1 phosphorylation activity and promotes cholesterol efflux from fibroblasts

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12 December 2020

Cholesterol accumulation in tissues of the Niemann-pick type C mouse is determined by the rate of lipoprotein-cholesterol uptake through the coated-pit pathway in each organ

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12 December 2020

Apolipoprotein A-I activates protein kinase C alpha signaling to phosphorylate and stabilize ATP binding cassette transporter A1 for the high density lipoprotein assembly

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12 December 2020

NPC1 and NPC2 Regulate Cellular Cholesterol Homeostasis through Generation of Low Density Lipoprotein Cholesterol-derived Oxysterols

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12 December 2020

Abnormal processing of Golgi elements and lysosomes in Tangier disease

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12 December 2020

Transmembrane molecular pump activity of Niemann-Pick C1 protein

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12 December 2020

Protein kinase A site-specific phosphorylation regulates ATP-binding cassette A1 (ABCA1)-mediated phospholipid efflux.

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12 December 2020

The Tangier disease gene product ABC1 controls the cellular apolipoprotein-mediated lipid removal pathway

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12 December 2020

Group C Niemann-Pick disease: faulty regulation of low-density lipoprotein uptake and cholesterol storage in cultured fibroblasts

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12 December 2020

Cholesterol efflux to apolipoprotein AI involves endocytosis and resecretion in a calcium-dependent pathway

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12 December 2020

Murine model of Niemann-Pick C disease: mutation in a cholesterol homeostasis gene

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12 December 2020

ABC1 promotes engulfment of apoptotic cells and transbilayer redistribution of phosphatidylserine

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12 December 2020

Apolipoprotein-mediated cellular cholesterol and phospholipid efflux depend on a functional Golgi apparatus

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12 December 2020

Association of ABCA1 with syntaxin 13 and flotillin-1 and enhanced phagocytosis in tangier cells

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12 December 2020

ABC1 gene expression and ApoA-I-mediated cholesterol efflux are regulated by LXR.

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12 December 2020

Niemann-Pick C heterozygosity confers resistance to lesional necrosis and macrophage apoptosis in murine atherosclerosis

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12 December 2020

Localization of Niemann-Pick C1 protein in astrocytes: implications for neuronal degeneration in Niemann- Pick type C disease

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12 December 2020

Localization of the murine Niemann-Pick C1 protein to two distinct intracellular compartments

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12 December 2020

10.1007/S00109-005-0001-9

Identifiers

DOI

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13 August 2017

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