(Q36347820)

English

Toll-like receptor 4 is expressed on intestinal stem cells and regulates their proliferation and apoptosis via the p53 up-regulated modulator of apoptosis

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Toll-like receptor 4 is expressed on intestinal stem cells and regulates their proliferation and apoptosis via the p53 up-regulated modulator of apoptosis (English)

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

apoptotic process

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toll-like receptor

0 references

author name string

Matthew D Neal

1

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Chhinder P Sodhi

2

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Hongpeng Jia

3

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Mitchell Dyer

4

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Charlotte E Egan

5

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Ibrahim Yazji

6

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Misty Good

7

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Amin Afrazi

8

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Ryan Marino

9

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Dennis Slagle

10

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Congrong Ma

11

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Maria F Branca

12

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Thomas Prindle

13

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Zachary Grant

14

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

John Ozolek

15

1 reference

Europe PubMed Central

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13 August 2017

David J Hackam

16

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

language of work or name

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publication date

6 September 2012

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Journal of Biological Chemistry

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Europe PubMed Central

PMC publication ID

13 August 2017

287

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

44

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

37296-37308

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Amniotic fluid inhibits Toll-like receptor 4 signaling in the fetal and neonatal intestinal epithelium.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481327

30 September 2017

LGR5 interacts and cointernalizes with Wnt receptors to modulate Wnt/β-catenin signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481327

30 September 2017

Intracellular heat shock protein-70 negatively regulates TLR4 signaling in the newborn intestinal epithelium.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481327

30 September 2017

Intact function of Lgr5 receptor-expressing intestinal stem cells in the absence of Paneth cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481327

30 September 2017

The intestinal stem cell markers Bmi1 and Lgr5 identify two functionally distinct populations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481327

30 September 2017

Regulation of the potential marker for intestinal cells, Bmi1, by β-catenin and the zinc finger protein KLF4: implications for colon cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481327

30 September 2017

Heparin-binding EGF-like growth factor protects intestinal stem cells from injury in a rat model of necrotizing enterocolitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481327

30 September 2017

Expansion of intestinal epithelial stem cells during murine development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481327

30 September 2017

A reserve stem cell population in small intestine renders Lgr5-positive cells dispensable

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481327

30 September 2017

Lgr5 homologues associate with Wnt receptors and mediate R-spondin signalling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481327

30 September 2017

p53 and PUMA independently regulate apoptosis of intestinal epithelial cells in patients and mice with colitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481327

30 September 2017

Interactions between the host innate immune system and microbes in inflammatory bowel disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481327

30 September 2017

PUMA-mediated intestinal epithelial apoptosis contributes to ulcerative colitis in humans and mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481327

30 September 2017

Drosophila Ras/MAPK signalling regulates innate immune responses in immune and intestinal stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481327

30 September 2017

c-Jun N-terminal phosphorylation antagonises recruitment of the Mbd3/NuRD repressor complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481327

30 September 2017

New insights into the pathogenesis and treatment of necrotizing enterocolitis: Toll-like receptors and beyond

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481327

30 September 2017

Bifidobacterium bifidum reduces apoptosis in the intestinal epithelium in necrotizing enterocolitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481327

30 September 2017

Intestinal stem cells and their roles during mucosal injury and repair

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481327

30 September 2017

Nucleotide-binding oligomerization domain-2 inhibits toll-like receptor-4 signaling in the intestinal epithelium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481327

30 September 2017

Invasive and indigenous microbiota impact intestinal stem cell activity through multiple pathways in Drosophila

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481327

30 September 2017

Toll-like receptor-4 inhibits enterocyte proliferation via impaired beta-catenin signaling in necrotizing enterocolitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481327

30 September 2017

Regeneration of intestinal stem/progenitor cells following doxorubicin treatment of mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481327

30 September 2017

PUMA suppresses intestinal tumorigenesis in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481327

30 September 2017

Sustained in vitro intestinal epithelial culture within a Wnt-dependent stem cell niche

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481327

30 September 2017

Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481327

30 September 2017

Reciprocal expression and signaling of TLR4 and TLR9 in the pathogenesis and treatment of necrotizing enterocolitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481327

30 September 2017

Bmi1 is expressed in vivo in intestinal stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481327

30 September 2017

PUMA regulates intestinal progenitor cell radiosensitivity and gastrointestinal syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481327

30 September 2017

Identification of stem cells in small intestine and colon by marker gene Lgr5

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481327

30 September 2017

p53 independent induction of PUMA mediates intestinal apoptosis in response to ischaemia-reperfusion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481327

30 September 2017

The roles of bacteria and TLR4 in rat and murine models of necrotizing enterocolitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481327

30 September 2017

Enterocyte TLR4 mediates phagocytosis and translocation of bacteria across the intestinal barrier

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481327

30 September 2017

Intestinal and hepatic expression of BNIP3 in necrotizing enterocolitis: regulation by nitric oxide and peroxynitrite

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481327

30 September 2017

Increased expression and function of integrins in enterocytes by endotoxin impairs epithelial restitution

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481327

30 September 2017

Essential requirement for Wnt signaling in proliferation of adult small intestine and colon revealed by adenoviral expression of Dickkopf-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481327

30 September 2017

p53- and drug-induced apoptotic responses mediated by BH3-only proteins puma and noxa

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481327

30 September 2017

Lipopolysaccharide modulation of normal enterocyte turnover by toll-like receptors is mediated by endogenously produced tumour necrosis factor alpha

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481327

30 September 2017

Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481327

30 September 2017

Efficient in vivo manipulation of mouse genomic sequences at the zygote stage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481327

30 September 2017

Lgr5 intestinal stem cells have high telomerase activity and randomly segregate their chromosomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481327

29 June 2018

JNK signalling modulates intestinal homeostasis and tumourigenesis in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481327

29 June 2018

EGF signaling activates proliferation and blocks apoptosis of mouse and human intestinal stem/progenitor cells in long-term monolayer cell culture.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481327

22 September 2018

Drosophila intestinal response to bacterial infection: activation of host defense and stem cell proliferation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481327

22 September 2018

A critical role for TLR4 in the pathogenesis of necrotizing enterocolitis by modulating intestinal injury and repair.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481327

22 September 2018

Stimulation and inhibition of proliferation in the small intestinal crypts of the mouse after in vivo administration of growth factors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481327

22 September 2018

Intestinal stem cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/22955282

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Necrotizing enterocolitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22955282

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M112.375881

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

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