(Q36365369)

English

Interleukin (IL)-6 induction of osteoclast differentiation depends on IL-6 receptors expressed on osteoblastic cells but not on osteoclast progenitors

scientific article published on November 1, 1995

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scholarly article

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Europe PubMed Central

PMC publication ID

13 August 2017

Interleukin (IL)-6 induction of osteoclast differentiation depends on IL-6 receptors expressed on osteoblastic cells but not on osteoclast progenitors (English)

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

0 references

positive regulation of biological process

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7595216

2 June 2024

author name string

N. Udagawa

1

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7595216

2 June 2024

N. Takahashi

2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7595216

2 June 2024

T. Katagiri

3

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7595216

2 June 2024

T. Tamura

4

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7595216

2 June 2024

S. Wada

5

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7595216

2 June 2024

D. M. Findlay

6

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7595216

2 June 2024

T. J. Martin

7

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7595216

2 June 2024

H. Hirota

8

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7595216

2 June 2024

T. Taga

9

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7595216

2 June 2024

T. Kishimoto

10

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7595216

2 June 2024

T. Suda

11

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7595216

2 June 2024

language of work or name

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publication date

1 November 1995

1 reference

Europe PubMed Central

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13 August 2017

full work available at URL

https://rupress.org/jem/article-pdf/182/5/1461/1107530/1461.pdf

Portable Document Format

online access status

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7595216

2 June 2024

https://europepmc.org/articles/PMC2192181

online access status

content deliverer

Europe PubMed Central

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7595216

2 June 2024

https://europepmc.org/articles/PMC2192181?pdf=render

Portable Document Format

online access status

content deliverer

Europe PubMed Central

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7595216

2 June 2024

https://rupress.org/jem/article-pdf/182/5/1461/1678081/1461.pdf

Portable Document Format

1 reference

10.1084/JEM.182.5.1461

https://api.crossref.org/works/10.1084/JEM.182.5.1461

2 June 2024

Journal of Experimental Medicine

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

182

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

5

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

1461-1468

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Generation of osteoclast-inductive and osteoclastogenic cell lines from the H-2KbtsA58 transgenic mouse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192181

30 September 2017

Cytokine signal transduction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192181

30 September 2017

Association and activation of Jak-Tyk kinases by CNTF-LIF-OSM-IL-6 beta receptor components

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192181

30 September 2017

Association of transcription factor APRF and protein kinase Jak1 with the interleukin-6 signal transducer gp130.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192181

30 September 2017

Soluble interleukin-6 receptor triggers osteoclast formation by interleukin 6

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192181

30 September 2017

Interleukin-6 deficient mice are protected from bone loss caused by estrogen depletion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192181

30 September 2017

Cloning of a murine IL-11 receptor alpha-chain; requirement for gp130 for high affinity binding and signal transduction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192181

30 September 2017

Mechanisms by which cells of the osteoblast lineage control osteoclast formation and activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192181

30 September 2017

Calcitonin receptor isoforms in mouse and rat osteoclasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192181

30 September 2017

Continuous activation of gp130, a signal-transducing receptor component for interleukin 6-related cytokines, causes myocardial hypertrophy in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192181

30 September 2017

Cloning and expression of the human interleukin-6 (BSF-2/IFN beta 2) receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192181

30 September 2017

Isolation and characterization of rat and human glyceraldehyde-3-phosphate dehydrogenase cDNAs: genomic complexity and molecular evolution of the gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192181

30 September 2017

IgG1 plasmacytosis in interleukin 6 transgenic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192181

30 September 2017

Interleukin-6 triggers the association of its receptor with a possible signal transducer, gp130

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192181

30 September 2017

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192181

30 September 2017

Proliferation of tartrate-resistant acid phosphatase positive multinucleate cells in ovariectomized animals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192181

30 September 2017

Origin of osteoclasts: mature monocytes and macrophages are capable of differentiating into osteoclasts under a suitable microenvironment prepared by bone marrow-derived stromal cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192181

30 September 2017

Glucocorticoid up-regulation of high-affinity interleukin 6 receptors on human epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192181

30 September 2017

Molecular cloning of a cDNA encoding interleukin 11, a stromal cell-derived lymphopoietic and hematopoietic cytokine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192181

30 September 2017

Isolation of a murine osteoclast colony-stimulating factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192181

30 September 2017

Molecular cloning of cDNA encoding adipogenesis inhibitory factor and identity with interleukin-11

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192181

30 September 2017

The Modulation of the Expression of IL-6 and Its Receptor in Human Osteoblastsin Vitro*

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192181

30 September 2017

Efficient selection for high-expression transfectants with a novel eukaryotic vector

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192181

30 September 2017

Modulation of osteoclast differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192181

30 September 2017

Interleukin-6 and its receptor: a paradigm for cytokines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192181

30 September 2017

Cytokine receptors and signal transduction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192181

30 September 2017

Identification of a 130-kilodalton tyrosine-phosphorylated protein induced by interleukin-11 as JAK2 tyrosine kinase, which associates with gp130 signal transducer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192181

28 June 2018

Regulation of bone marrow stromal cell differentiation by cytokines whose receptors share the gp130 protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192181

28 June 2018

Glucocorticoid regulation of calcitonin receptor in mouse osteoclast-like multinucleated cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192181

28 June 2018

Interleukin-11 inhibits adipogenesis and stimulates myelopoiesis in human long-term marrow cultures

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192181

28 June 2018

Role of osteoblasts in hormonal control of bone resorption—A hypothesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192181

28 June 2018

Osteoblastic cells are involved in osteoclast formation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192181

28 June 2018

Generation of osteoclasts from isolated hematopoietic progenitor cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192181

28 June 2018

IL-6 is produced by osteoblasts and induces bone resorption

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192181

28 June 2018

Preparation of soluble murine IL-6 receptor and anti-murine IL-6 receptor antibodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192181

28 June 2018

Chinese hamster ovarian cells transfected with the murine interleukin-6 gene cause hypercalcemia as well as cachexia, leukocytosis and thrombocytosis in tumor-bearing nude mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192181

28 June 2018

Characterization of interleukin-11 receptor and protein tyrosine phosphorylation induced by interleukin-11 in mouse 3T3-L1 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192181

28 June 2018

Pathogenesis of hypercalcemia in lymphosarcoma cell leukemia. Role of an osteoclast activating factor-like substance and a mechanism of action for glucocorticoid therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192181

28 June 2018

Etl2, a novel putative type-I cytokine receptor expressed during mouse embryogenesis at high levels in skin and cells with skeletogenic potential

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192181

22 September 2018

Second messenger signaling of PTH- and PTHRP-stimulated osteoclast-like cell formation from hemopoietic blast cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/7595216

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The cellular basis of bone resorption

1 reference

https://pubmed.ncbi.nlm.nih.gov/7595216

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of Insulin-Like Growth Factor I Receptors on Cultured Rat Bone Cells: Regulation of Receptor Concentration by Glucocorticoids*

1 reference

https://pubmed.ncbi.nlm.nih.gov/7595216

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional expression of a microinjected Ed alpha gene in C57BL/6 transgenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/7595216

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Beta-adrenergic receptors in hamster smooth muscle cells are transcriptionally regulated by glucocorticoids

1 reference

https://pubmed.ncbi.nlm.nih.gov/7595216

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glucocorticoids impair bone resorptive activity and viability of osteoclasts disaggregated from neonatal rat long bones

1 reference

https://pubmed.ncbi.nlm.nih.gov/7595216

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calcitonin receptors as markers for osteoclastic differentiation: correlation between generation of bone-resorptive cells and cells that express calcitonin receptors in mouse bone marrow cultures

1 reference

https://pubmed.ncbi.nlm.nih.gov/7595216

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Parathyroid hormone (PTH) and PTH-like protein (PLP) stimulate interleukin-6 production by osteogenic cells: a possible role of interleukin-6 in osteoclastogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/7595216

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The bone marrow-derived stromal cell lines MC3T3-G2/PA6 and ST2 support osteoclast-like cell differentiation in cocultures with mouse spleen cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/7595216

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glucocorticoids stimulate resorption in fetal rat parietal bones in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/7595216

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Deficiency of osteoclasts in osteopetrotic mice is due to a defect in the local microenvironment provided by osteoblastic cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/7595216

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human osteoblastlike cells do not respond to interleukin-6

1 reference

https://pubmed.ncbi.nlm.nih.gov/7595216

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of prostaglandins in interleukin-1-induced bone resorption in mice in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/7595216

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased osteoclast development after estrogen loss: mediation by interleukin-6

1 reference

https://pubmed.ncbi.nlm.nih.gov/7595216

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for an autocrine/paracrine role for interleukin-6 in bone resorption by giant cells from giant cell tumors of bone

1 reference

https://pubmed.ncbi.nlm.nih.gov/7595216

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neutralizing antibodies to human interleukin 6 reverse hypercalcemia associated with a human squamous carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/7595216

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1084/JEM.182.5.1461

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

ResearchGate publication ID

0 references

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