(Q36366984)

13 August 2017

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title

Relevance of glutamine metabolism to tumor cell growth (English)

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ORCID Public Data File 2021

13 August 2017

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author name string

Medina MA

1

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13 August 2017

Sánchez-Jiménez F

2

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13 August 2017

Márquez J

3

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13 August 2017

Rodríguez Quesada A

4

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13 August 2017

Núñez de Castro I

5

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13 August 2017

1 July 1992

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Molecular and Cellular Biochemistry

13 August 2017

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13 August 2017

113

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13 August 2017

1

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13 August 2017

1-15

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https://scigraph.springernature.com/pub.10.1007/bf00230880

13 August 2017

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cites work

Competition for host essential and nonessential fatty acids by Ehrlich ascites carcinoma in mice.

1 reference

12 December 2020

Growth of pancreatic foci and development of pancreatic cancer with a single dose of azaserine in the rat.

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12 December 2020

Renal metabolism of amino acids and ammonia in subjects with normal renal function and in patients with chronic renal insufficiency.

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12 December 2020

Protein metabolism in the tumour-bearing mouse. Rates of protein synthesis in host tissues and in an Ehrlich ascites tumour at different stages in tumour growth

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12 December 2020

Glutamine metabolism in skeletal muscles from the broiler chick (Gallus domesticus) and the laboratory rat (Rattus norvegicus)

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12 December 2020

Glutamine-enriched diets support muscle glutamine metabolism without stimulating tumor growth

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12 December 2020

Overview of mitochondrial metabolite transport systems

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12 December 2020

Localization and some properties of phosphate-dependent glutaminase in disrupted liver mitochondria

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12 December 2020

Importance of the flux of phosphate across the inner membrane of kidney mitochondria for the activation of glutaminase and the transport of glutamine

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12 December 2020

Hepatic Glutamine Metabolism under the Influence of the Portal Ammonia Concentration in the Perfused Rat Liver

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12 December 2020

Metabolic alterations in cancer. Part II. Protein and fat metabolism

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12 December 2020

[Inactivation of microbial glutamin-(asparagin-)ase by azaserine and 6-diazo-5-oxo-L-norleucine]

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12 December 2020

Evidence for an essential sulfhydryl group at the substrate binding site of the A-system transporter of Ehrlich cell plasma membranes

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12 December 2020

Electrogenic amino acid transport

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12 December 2020

Species differences in renal glutamine synthesis in vivo.

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12 December 2020

The Inhibitory Effects of Sulphydryl Reagents on the Transport and Hydrolysis of Glutamine in Rat-Liver Mitochondria

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12 December 2020

A quantitative approach to metabolic control

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12 December 2020

Uptake of glutamine antimetabolites 6-diazo-5-oxo-L-norleucine (DON) and acivicin in sensitive and resistant tumor cell lines

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12 December 2020

Patterns of amino acid biosynthesis from labeled glucose

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12 December 2020

Evidence that glutamine, not sugar, is the major energy source for cultured HeLa cells

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12 December 2020

Uptake and metabolism of plasma glutamine by the small intestine

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12 December 2020

Glycolysis, glutaminolysis and cell proliferation

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12 December 2020

Phase II study of acivicin in non-small cell lung cancer: a National Cancer Institute of Canada Study

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12 December 2020

Phase II trial of acivicin in patients with advanced epithelial ovarian carcinoma. A Gynecologic Oncology Group Study.

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12 December 2020

Hepatic glutaminase flux regulation of glutamine homeostasis. Studies in vivo

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12 December 2020

The effect of an Ehrlich ascites tumour on the rate of protein synthesis in muscle and liver of the host [proceedings]

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12 December 2020

Glutamine transport and metabolism by mitochondria from dog renal cortex. General properties and response to acidosis and alkalosis

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12 December 2020

L-glutamine: a major substrate for tumor cells in vivo?

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12 December 2020

The effect of metabolic acidosis on the synthesis and turnover of rat renal phosphate-dependent glutaminase

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12 December 2020

Metabolic alterations in cancer. Part I. Carbohydrate metabolism.

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12 December 2020

Metabolism and action of amino acid analog anti-cancer agents

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12 December 2020

Tumor-caused changes in host protein synthesis under different dietary situations

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12 December 2020

Effects of acivicin and dichloroallyl lawsone upon pyrimidine biosynthesis in mouse L1210 leukemia cells

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12 December 2020

Factors regulating amino acid release from extrasplanchnic tissues in the rat. Interactions of alanine and glutamine

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12 December 2020

Arteriovenous differences for amino acids and lactate across kidneys of normal and acidotic rats

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12 December 2020

Glutamine synthetase and glutamyltransferase in the kidney of man, dog, and rat

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12 December 2020

Glutamine transport by mitochondria isolated from normal and acidotic rats

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12 December 2020

Measurements of the turnover rate of glutamine in normal and acidotic rats

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12 December 2020

Malate-citrate cycle during glycolysis and glutaminolysis in Ehrlich ascites tumor cells

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12 December 2020

Amino acid utilization and urine protein excretion in children treated with succinylated Acinetobacter glutaminase-asparaginase

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12 December 2020

Nutrition and cancer: physiological interrelationships

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12 December 2020

Reduction of tumor growth following treatment with a glutamine antimetabolite

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12 December 2020

Amino acids and glucose utilization by different metabolic pathways in ascites-tumour cells

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12 December 2020

Control of enzymic programs and nucleotide pattern in cancer cells by acivicin and tiazofurin

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12 December 2020

Mouse liver free amino acids during the development of Ehrlich ascites tumour

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12 December 2020

Metabolic patterns for glucose-1-C14 in tissues of tumor-bearing rats

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12 December 2020

Effect of acivicin on glutamine transport by rat renal brush border membrane vesicles

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12 December 2020

Glutamine synthetase and glutaminase activities in various hepatoma cells

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12 December 2020

Direct methods for measuring metabolite transport and distribution in mitochondria

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12 December 2020

Nitrogen utilization in mice bearing Ehrlich ascites tumor treated with Acinetobacter glutaminase-asparaginase

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12 December 2020

Interaction of azaserine and raw soya flour on the rat pancreas

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12 December 2020

Simple and effective purification of a Na+-dependent amino acid transport system from Ehrlich ascites cell plasma membrane

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12 December 2020

Role of amino acid transport and countertransport in nutrition and metabolism

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12 December 2020

A comparative study of glytaminase isozymes in rat tissues

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12 December 2020

Regulation of renal ammoniagenesis. Subcellular localization of rat kidney glutaminase isoenzymes

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12 December 2020

Multi-enzyme-targeted chemotherapy by acivicin and actinomycin

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12 December 2020

The function of redox shuttles during aerobic glycolysis in two strains of Ehrlich ascites tumor cells.

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12 December 2020

Insulin and acivicin improve host nutrition and prevent tumor growth during total parenteral nutrition

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12 December 2020

Respiration of mitochondria isolated from differentiated and undifferentiated HT29 colon cancer cells in the presence of various substrates and ADP generating systems

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12 December 2020

Renal mitochondrial glutamine transport and metabolism: studies with a rapid-mixing, rapid-filtration technique

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12 December 2020

Asparaginase as a drug for treatment of acute lymphoblastic leukaemia.

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12 December 2020

Glutamine transport in submitochondrial particles

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12 December 2020

Metabolite Transport in Mitochondria

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12 December 2020

Characteristics of an amino acid transport system in rat liver for glutamine, asparagine, histidine, and closely related analogs

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12 December 2020

Glutamine: a major energy source for cultured mammalian cells.

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12 December 2020

Hepatocyte heterogeneity in glutamine and ammonia metabolism and the role of an intercellular glutamine cycle during ureogenesis in perfused rat liver

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12 December 2020

The effects of tumour necrosis factor-alpha (cachectin) and tumour growth on hepatic amino acid utilization in the rat.

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12 December 2020

Bioenergetics of tumor cells: glutamine metabolism in tumor cell mitochondria

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12 December 2020

Glutaminolysis and glycolysis interactions in proliferant cells

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12 December 2020

The possible role of glutamine substrate cycles in skeletal muscle

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12 December 2020

Altered ornithine metabolism in tumor-bearing mice

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12 December 2020

The pathways of glutamate and glutamine oxidation by tumor cell mitochondria. Role of mitochondrial NAD(P)+-dependent malic enzyme

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12 December 2020

Contribution by host tissues to circulating glutamine in mice inoculated with Ehrlich ascites tumor cells

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12 December 2020

Purification, kinetic behavior, and regulation of NAD(P)+ malic enzyme of tumor mitochondria

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12 December 2020

In vitro and in vivo anti-tumor activity of L-glutamic acid gamma-monohydroxamate against L1210 leukemia and B16 melanoma

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12 December 2020

Some aspects of nitrogen and energy metabolism in cancerous subjects: a review.

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12 December 2020

COMPARATIVE BIOCHEMISTRY OF HEPATOMAS. V. STUDIES ON AMINO ACID INCORPORATION IN LIVER TUMORS OF DIFFERENT GROWTH RATES

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12 December 2020

The rediscovery of DON (6-diazo-5-oxo-L-norleucine)

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12 December 2020

Inactivation by acivicin of carbamoyl-phosphate synthetase II of human colon carcinoma

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12 December 2020

Altered amino acid kinetics in rats with progressive tumor growth

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12 December 2020

Amino acid extraction and ammonia metabolism by the human kidney during the prolonged administration of ammonium chloride

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12 December 2020

Enhancement of antitumor activity of glutamine antagonists 6-diazo-5-oxo-L-norleucine and acivicin in cell culture by glutaminase-asparaginase.

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12 December 2020

DISTINCT MEDIATING SYSTEMS FOR THE TRANSPORT OF NEUTRAL AMINO ACIDS BY THE EHRLICH CELL

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12 December 2020

The energy state of tumor-bearing rats.

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12 December 2020

Glutaminase of the human malignant cell, strain HeLa

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12 December 2020

Prevention of central nervous system toxicity of the antitumor antibiotic acivicin by concomitant infusion of an amino acid mixture

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12 December 2020

Amino Acid Metabolism in Man

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12 December 2020

Evidence of an intracellular dissipative structure

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12 December 2020

Phase II trial of acivicin in patients with advanced colorectal carcinoma

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12 December 2020

Measurement of ‘in situ’ mitochondrial membrane potential in Ehrlich ascites tumor cells during aerobic glycolysis

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12 December 2020

Response of tumor and host to hyperalimentation and antiglutamine treatments

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12 December 2020

Inorganic phosphate and energy charge compartmentation in Ehrlich ascites tumour cells in the presence of glucose and/or glutamine

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12 December 2020

Ketone body, glucose, lactic acid, and amino acid utilization by tumors in vivo in fasted rats.

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12 December 2020

Acivicin. An antitumor antibiotic

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12 December 2020

L-glutamine transport in native vesicles isolated from Ehrlich ascites tumor cell membranes.

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12 December 2020

Glucagon and epinephrine effect on blood glucose levels in rats carrying Yoshida solid sarcoma and Walker-256 carcinosarcoma

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12 December 2020

25 Methodology for transport studies: Graphical and computer curve fitting methods for glutamate and aspartate efflux kinetics

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12 December 2020

Phase II trial of 6-diazo-5-oxo-L-norleucine versus aclacinomycin-A in advanced sarcomas and mesotheliomas

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12 December 2020

Enzyme targets of antiglutamine agents in cancer chemotherapy

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12 December 2020

Early systemic effects on the hepatic mitochondria of tumour bearing mice

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12 December 2020

Biochemical pharmacology of acivicin in rat hepatoma cells

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12 December 2020

The transport and metabolism of glutamine by kidney-cortex mitochondria from normal and acidotic rats

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12 December 2020

On the multiform relationships between the tumor and the host

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12 December 2020

Distribution of hepatic glutaminase activity and mRNA in perivenous and periportal rat hepatocytes

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12 December 2020

Effect of l-glutamine antagonists on 5-phosphoribosyl 1-pyrophosphate levels in p388 leukemia and in murine colon adenocarcinomas in vivo

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12 December 2020

Glycolysis and glutaminolysis in perifused Ehrlich ascites tumour cells

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12 December 2020

Glutamine and glucose metabolism during thymocyte proliferation. Pathways of glutamine and glutamate metabolism

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12 December 2020

Kinetics of cell proliferation and polyamine synthesis during Ehrlich ascites tumor growth

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12 December 2020

Conditions for activity of glutaminase in kidney mitochondria

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12 December 2020

Regulation of flux through glutaminase and glutamine synthetase in isolated perfused rat liver

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12 December 2020

The Utilization of Unesterified Palmitate by Ehrlich Ascites Tumor Cells

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12 December 2020

A distinct Na+-requiring transport system for alanine, serine, cysteine, and similar amino acids

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12 December 2020

The metabolic environment of cancer

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12 December 2020

Malignancy and tissue metabolism.

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12 December 2020

Azaserine, DON, and azotomycin: three diazo analogs of L-glutamine with clinical antitumor activity

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12 December 2020

Enhancement of the sensitivity of human colon cancer cells to growth inhibition by acivicin achieved through inhibition of nucleic acid precursor salvage by dipyridamole

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12 December 2020

Cellular compartmentation of Ehrlich ascites tumor cells

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12 December 2020

Neoplastic transformation of newborn rat astrocytes in culture.

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12 December 2020

Purification of phosphate-dependent glutaminase from isolated mitochondria of Ehrlich ascites-tumour cells.

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12 December 2020

Glutamine metabolism in the rat

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12 December 2020

Glutamine and glucose as energy substrates for Ehrlich ascites tumour cells

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12 December 2020

Efficacy of 6-diazo-5-oxo-L-norleucine and N-[N-gamma-glutamyl-6-diazo-5-oxo-norleucinyl]-6-diazo-5-oxo-norleucine against experimental tumors in conventional and nude mice

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12 December 2020

Mitochondrial metabolism of glutamine and glutamate and its physiological significance

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12 December 2020

Effect of palmitate, acetate and glucose on glutamine metabolism in Ehrlich ascites tumor cells

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12 December 2020

The metabolic fate of 13N-labeled ammonia in rat brain

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12 December 2020

Early development of protein metabolic perturbations in the liver and skeletal muscle of tumour-bearing rats. A model system for cancer cachexia

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12 December 2020

Kinetics of glutamine-efflux from liver mitochondria loaded with the 14C-Labeled substrate

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12 December 2020

Substrate-specificity of glutamine transporters in membrane vesicles from rat liver and skeletal muscle investigated using amino acid analogues

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12 December 2020

31P-NMR studies of glucose and glutamine metabolism in cultured mammalian cells

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12 December 2020

Effects of the combination of acivicin and cis-diamminedichloroplatinum(II) on thymidylate synthesis of A549 lung cancer cells

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12 December 2020

Phase I and pharmacokinetic studies of DON

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12 December 2020

Glutamine metabolism in Ehrlich ascites-carcinoma cells

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12 December 2020

Nitrogen metabolism in tumor bearing mice

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12 December 2020

The Enzymic Pattern of Neoplastic Tissue

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12 December 2020

Fatty acid oxidation to H2O by Ehrlich ascites carcinoma in mice

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12 December 2020

Inhibition of tumor cell glutamine uptake by isolated neutrophils

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12 December 2020

Nitrogen movement between host and tumor in mice inoculated with Ehrlich ascitic tumor cells

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12 December 2020

Identifiers

DOI

10.1007/BF00230880

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13 August 2017

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