(Q36367885)

English

Cure of progressive murine leishmaniasis: interleukin 4 dominance is abolished by transient CD4(+) T cell depletion and T helper cell type 1-selective cytokine therapy

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Cure of progressive murine leishmaniasis: interleukin 4 dominance is abolished by transient CD4(+) T cell depletion and T helper cell type 1-selective cytokine therapy (English)

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

author name string

F P Heinzel

1

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

R M Rerko

2

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

language of work or name

0 references

publication date

1 June 1999

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Journal of Experimental Medicine

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

189

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

12

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

1895-1906

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Genetic regulation of commitment to interleukin 4 production by a CD4(+) T cell-intrinsic mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192969

30 September 2017

Interleukin-13: central mediator of allergic asthma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192969

30 September 2017

T helper type 2 inflammatory disease in the absence of interleukin 4 and transcription factor STAT6.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192969

30 September 2017

Effective and long-lasting immunity against the parasite Leishmania major in CD8-deficient mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192969

30 September 2017

Differential regulation of the interleukin-12 receptor during the innate immune response to Leishmania major.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192969

30 September 2017

IL-13, IL-4Ralpha, and Stat6 are required for the expulsion of the gastrointestinal nematode parasite Nippostrongylus brasiliensis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192969

30 September 2017

A role for CD4 in peripheral T cell differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192969

30 September 2017

Treatment with depleting CD4 monoclonal antibody results in a preferential loss of circulating naive T cells but does not affect IFN-gamma secreting TH1 cells in humans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192969

30 September 2017

A T helper cell 2 (Th2) immune response against non-self antigens modifies the cytokine profile of autoimmune T cells and protects against experimental allergic encephalomyelitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192969

30 September 2017

Regulation of the interleukin (IL)-12R beta 2 subunit expression in developing T helper 1 (Th1) and Th2 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192969

30 September 2017

In differentiated CD4+ T cells, interleukin 4 production is cytokine-autonomous, whereas interferon gamma production is cytokine-dependent

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192969

30 September 2017

Limited role of CD28-mediated signals in T helper subset differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192969

30 September 2017

The Th1/Th2 balance in autoimmunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192969

30 September 2017

Targeted activation of CD8 cells and infection of beta 2-microglobulin-deficient mice fail to confirm a primary protective role for CD8 cells in experimental leishmaniasis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192969

30 September 2017

Resolution of cutaneous leishmaniasis: interleukin 12 initiates a protective T helper type 1 immune response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192969

30 September 2017

Effects of interleukin 12 on immune responses and host protection in mice infected with intestinal nematode parasites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192969

30 September 2017

Interferon gamma-independent effects of interleukin 12 administered during acute or established infection due to Leishmania major

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192969

30 September 2017

Switch from a type 2 to a type 1 T helper cell response and cure of established Leishmania major infection in mice is induced by combined therapy with interleukin 12 and Pentostam

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192969

30 September 2017

The regulation of immunity to Leishmania major

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192969

30 September 2017

The effect of antigen dose on CD4+ T helper cell phenotype development in a T cell receptor-alpha beta-transgenic model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192969

30 September 2017

Interleukin 12 inhibits antigen-induced airway hyperresponsiveness, inflammation, and Th2 cytokine expression in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192969

30 September 2017

Attenuation of gamma interferon-induced tyrosine phosphorylation in mononuclear phagocytes infected with Leishmania donovani: selective inhibition of signaling through Janus kinases and Stat1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192969

30 September 2017

Therapeutic monoclonal antibodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192969

30 September 2017

Prevention of experimental autoimmune encephalomyelitis by antibodies against interleukin 12.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192969

30 September 2017

Cytokine-induced immune deviation as a therapy for inflammatory autoimmune disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192969

30 September 2017

Prevention of type II collagen-induced arthritis by in vivo treatment with anti-L3T4

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192969

30 September 2017

Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192969

30 September 2017

Reprogramming the immune system for peripheral tolerance with CD4 and CD8 monoclonal antibodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192969

30 September 2017

IL-4-induced immune deviation as antigen-specific therapy for inflammatory autoimmune disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192969

30 September 2017

CpG oligodeoxynucleotides trigger protective and curative Th1 responses in lethal murine leishmaniasis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192969

28 June 2018

In vivo production and function of IL-12 p40 homodimers.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192969

28 June 2018

Modulating autoimmune responses to GAD inhibits disease progression and prolongs islet graft survival in diabetes-prone mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192969

28 June 2018

Induction of TH1 and TH2 immunity in neonatal mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192969

28 June 2018

Effect of anti-CD4 on CD4 subsets. I. Anti-CD4 preferentially deletes resting, naive CD4 cells and spares activated CD4 cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192969

28 June 2018

Murine cutaneous leishmaniasis: resistance correlates with the capacity to generate interferon-gamma in response to Leishmania antigens in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192969

28 June 2018

Establishment of resistance to Leishmania major infection in susceptible BALB/c mice requires parasite-specific CD8+ T cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192969

28 June 2018

A possible novel pathway of regulation by murine T helper type-2 (Th2) cells of a Th1 cell activity via the modulation of the induction of nitric oxide synthase on macrophages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192969

28 June 2018

Development of murine lupus in CD4-depleted NZB/NZW mice. Sustained inhibition of residual CD4+ T cells is required to suppress autoimmunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192969

28 June 2018

Requirement for IL-13 independently of IL-4 in experimental asthma

1 reference

https://api.crossref.org/works/10.1084%2FJEM.189.12.1895

21 January 2018

Underproduction of interleukin-12 in susceptible mice during progressive leishmaniasis is due to decreased CD40 activity

1 reference

https://api.crossref.org/works/10.1084%2FJEM.189.12.1895

21 January 2018

Differential effects of interleukin-12 on the development of naive mouse CD4+ T cells.

1 reference

https://api.crossref.org/works/10.1084%2FJEM.189.12.1895

21 January 2018

Impaired Th2 subset development in the absence of CD4.

1 reference

https://api.crossref.org/works/10.1084%2FJEM.189.12.1895

21 January 2018

Generation and in vivo persistence of polarized Th1 and Th2 memory cells

1 reference

https://api.crossref.org/works/10.1084%2FJEM.189.12.1895

21 January 2018

Differential effects of blockade of CD28-B7 on the development of Th1 or Th2 effector cells in experimental leishmaniasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192969

21 September 2018

Analysis of cytokine production by inflammatory mouse macrophages at the single-cell level: selective impairment of IL-12 induction in Leishmania-infected cells

1 reference

https://api.crossref.org/works/10.1084%2FJEM.189.12.1895

21 January 2018

Administration of recombinant IL-12 to normal mice enhances cytolytic lymphocyte activity and induces production of IFN-gamma in vivo

1 reference

https://api.crossref.org/works/10.1084%2FJEM.189.12.1895

21 January 2018

Resistance to Leishmania major induced by tolerance to a single antigen

1 reference

https://api.crossref.org/works/10.1084%2FJEM.189.12.1895

21 January 2018

Blockade of CD86 ameliorates Leishmania major infection by down-regulating the Th2 response

1 reference

https://api.crossref.org/works/10.1084%2FJEM.189.12.1895

21 January 2018

Administration of IL-12 during ongoing immune responses fails to permanently suppress and can even enhance the synthesis of antigen-specific IgE

1 reference

https://api.crossref.org/works/10.1084%2FJEM.189.12.1895

21 January 2018

Induction of immune tolerance during administration of monoclonal antibody to L3T4 does not depend on depletion of L3T4+ cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/10377185

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IL-4 induces a Th2 response in Leishmania major-infected mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/10377185

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IL-2 is necessary for the progression of leishmaniasis in susceptible murine hosts

1 reference

https://pubmed.ncbi.nlm.nih.gov/10377185

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differences in the degree of depletion, rate of recovery, and the preferential elimination of naive CD4+ T cells by anti-CD4 monoclonal antibody (GK1.5) in young and aged mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/10377185

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Endogenous IL-12 is required for control of Th2 cytokine responses capable of exacerbating leishmaniasis in normally resistant mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/10377185

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of cutaneous dendritic cells by CpG-containing oligodeoxynucleotides: a role for dendritic cells in the augmentation of Th1 responses by immunostimulatory DNA

1 reference

https://pubmed.ncbi.nlm.nih.gov/10377185

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Early production of IL-4 in susceptible mice infected with Leishmania major rapidly induces IL-12 unresponsiveness

1 reference

https://pubmed.ncbi.nlm.nih.gov/10377185

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1084/JEM.189.12.1895

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

ResearchGate publication ID

0 references

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