(Q36369136)

13 August 2017

Contribution of itraconazole metabolites to inhibition of CYP3A4 in vivo (English)

1 reference

13 August 2017

I E Templeton

1

1 reference

13 August 2017

K E Thummel

2

1 reference

13 August 2017

E D Kharasch

3

1 reference

13 August 2017

K L Kunze

4

1 reference

13 August 2017

C Hoffer

5

1 reference

13 August 2017

W L Nelson

6

1 reference

13 August 2017

N Isoherranen

7

1 reference

13 August 2017

language of work or name

English

0 references

publication date

9 May 2007

1 reference

Clinical Pharmacology & Therapeutics

13 August 2017

1 reference

13 August 2017

83

1 reference

13 August 2017

1

1 reference

13 August 2017

77-85

1 reference

Stereochemical aspects of itraconazole metabolism in vitro and in vivo

13 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488349

CYP3A4 substrate selection and substitution in the prediction of potential drug-drug interactions

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488349

Disposition of posaconazole following single-dose oral administration in healthy subjects

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488349

Role of itraconazole metabolites in CYP3A4 inhibition

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488349

Prediction of midazolam-CYP3A inhibitors interaction in the human liver from in vivo/in vitro absorption, distribution, and metabolism data.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488349

Enhanced bioavailability of itraconazole in hydroxypropyl-beta-cyclodextrin solution versus capsules in healthy volunteers.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488349

Itraconazole. A reappraisal of its pharmacological properties and therapeutic use in the management of superficial fungal infections

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488349

Food interaction and steady-state pharmacokinetics of itraconazole capsules in healthy male volunteers

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488349

Pharmacokinetic optimisation of oral antifungal therapy

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488349

Pharmacokinetics of itraconazole following oral administration to normal volunteers

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488349

The clinical pharmacokinetics of itraconazole: an overview

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488349

Quantitative prediction of metabolic inhibition of midazolam by itraconazole and ketoconazole in rats: implication of concentrative uptake of inhibitors into liver.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488349

Optimisation of itraconazole therapy using target drug concentrations.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488349

Simvastatin but not pravastatin is very susceptible to interaction with the CYP3A4 inhibitor itraconazole.

28 June 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100230

The effects of the systemic antimycotics, itraconazole and fluconazole, on the pharmacokinetics and pharmacodynamics of intravenous and oral midazolam.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100230

The area under the plasma concentration-time curve for oral midazolam is 400-fold larger during treatment with itraconazole than with rifampicin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100230

Beneficial pharmacokinetic interaction between cyclosporine and itraconazole in renal transplant recipients

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100230

Tacrolimus dosage requirements after initiation of azole antifungal therapy in pediatric thoracic organ transplantation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100230

Coadministration of itraconazole and tacrolimus after thoracic organ transplantation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100230

Surface plasmon resonance analysis of antifungal azoles binding to CYP3A4 with kinetic resolution of multiple binding orientations

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100230

Capillary electrophoresis evidence for the stereoselective metabolism of itraconazole in man.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100230

Identification of human UDP-glucuronosyltransferase enzyme(s) responsible for the glucuronidation of posaconazole (Noxafil).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100230

Antimycotic azoles. 7. Synthesis and antifungal properties of a series of novel triazol-3-ones

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100230

Evaluation of the protein binding ratio of drugs by a micro-scale ultracentrifugation method

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100230

Pharmacokinetics of midazolam in anaesthetized cirrhotic patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100230

Prediction of cytochrome P450 3A inhibition by verapamil enantiomers and their metabolites

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100230

Interaction of cyclosporin and itraconazole

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17495874

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Effect of itraconazole on the single oral dose pharmacokinetics and pharmacodynamics of alprazolam

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17495874

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/SJ.CLPT.6100230

1 reference

13 August 2017

1 reference

13 August 2017

PubMed publication ID

17495874

1 reference