(Q36370360)

English

Mode of action: inhibition of histone deacetylase, altering WNT-dependent gene expression, and regulation of beta-catenin--developmental effects of valproic acid

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scholarly article

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Europe PubMed Central

13 August 2017

1 reference

Europe PubMed Central

Mode of action: inhibition of histone deacetylase, altering WNT-dependent gene expression, and regulation of beta-catenin--developmental effects of valproic acid (English)

1 reference

Europe PubMed Central

13 August 2017

author name string

Jeanette Wiltse

1

1 reference

Europe PubMed Central

13 August 2017

language of work or name

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publication date

1 October 2005

1 reference

Europe PubMed Central

13 August 2017

Critical Reviews in Toxicology

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Europe PubMed Central

13 August 2017

35

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Europe PubMed Central

13 August 2017

8-9

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Europe PubMed Central

13 August 2017

727-738

1 reference

Europe PubMed Central

13 August 2017

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Wnt signaling: a common theme in animal development

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Failure of periconceptual folic acid to prevent a neural tube defect in the offspring of a mother taking sodium valproate

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Subgenual prefrontal cortex abnormalities in mood disorders.

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Repeated neural tube defects and valproate monotherapy suggest a pharmacogenetic abnormality

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A mouse model for valproate teratogenicity: parental effects, homeotic transformations, and altered HOX expression.

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Neural crest cell motility in valproic acid

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The Wnt signaling pathway in bipolar disorder

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Lithium and valproic acid: parallels and contrasts in diverse signaling contexts

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Axonal remodeling and synaptic differentiation in the cerebellum is regulated by WNT-7a signaling

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Valproate regulates GSK-3-mediated axonal remodeling and synapsin I clustering in developing neurons

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Valproic acid induces apoptosis in human leukemia cells by stimulating both caspase-dependent and -independent apoptotic signaling pathways

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WNT-7a induces axonal remodeling and increases synapsin I levels in cerebellar neurons

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PKC, MAP kinases and the bcl-2 family of proteins as long-term targets for mood stabilizers

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Teratogenic effects of sodium valproate in mice and rats at midgestation and at term

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Amelioration of sodium valproate‐induced neural tube defects in mouse fetuses by maternal folic acid supplementation during gestation

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Wnt signaling in oncogenesis and embryogenesis--a look outside the nucleus

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Histone deacetylase is a direct target of valproic acid, a potent anticonvulsant, mood stabilizer, and teratogen

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The evolution of signalling pathways in animal development

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Maternal valproic acid and congenital neural tube defects

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Lithium inhibits glycogen synthase kinase-3 activity and mimics wingless signalling in intact cells

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Valproic acid-induced neural tube defects: reduction by folinic acid in the mouse

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Neural tube closure requires Dishevelled-dependent convergent extension of the midline

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Wnt signaling, Ca2+, and cyclic GMP: visualizing Frizzled functions

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Diurnal variation of folate concentrations in mouse embryo and plasma: The protective effect of folinic acid on valproic-acid-induced teratogenicity is time dependent

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Identifiers

10.1080/10408440591007403

1 reference

Europe PubMed Central

13 August 2017

1 reference

Europe PubMed Central

13 August 2017

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