(Q36372605)

13 August 2017

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title

Pulmonary arterial hypertension: new insights and new hope (English)

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13 August 2017

main subject

arterial hypertension

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author name string

Kevin B Martin

series ordinal

1

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13 August 2017

James R Klinger

series ordinal

2

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13 August 2017

Sharon I S Rounds

series ordinal

3

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13 August 2017

language of work or name

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1 January 2006

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13 August 2017

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13 August 2017

volume

11

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13 August 2017

issue

1

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13 August 2017

page(s)

6-17

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Clinical classification of pulmonary hypertension.

13 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1843.2006.00778.X

Sporadic primary pulmonary hypertension is associated with germline mutations of the gene encoding BMPR-II, a receptor member of the TGF-beta family

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1843.2006.00778.X

Familial primary pulmonary hypertension (gene PPH1) is caused by mutations in the bone morphogenetic protein receptor-II gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1843.2006.00778.X

Genetic basis of pulmonary arterial hypertension: current understanding and future directions

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1843.2006.00778.X

Serotonin transporter overexpression is responsible for pulmonary artery smooth muscle hyperplasia in primary pulmonary hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1843.2006.00778.X

Primary pulmonary hypertension. A national prospective study

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1843.2006.00778.X

Survival in patients with primary pulmonary hypertension. Results from a national prospective registry.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1843.2006.00778.X

Haemodynamic evaluation of pulmonary hypertension.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1843.2006.00778.X

A comparison of continuous intravenous epoprostenol (prostacyclin) with conventional therapy for primary pulmonary hypertension

21 January 2018

1 reference

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Reduction in pulmonary vascular resistance with long-term epoprostenol (prostacyclin) therapy in primary pulmonary hypertension.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1843.2006.00778.X

Survival in primary pulmonary hypertension: the impact of epoprostenol therapy.

21 January 2018

1 reference

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Continuous subcutaneous infusion of treprostinil, a prostacyclin analogue, in patients with pulmonary arterial hypertension: a double-blind, randomized, placebo-controlled trial.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1843.2006.00778.X

Inhaled iloprost for severe pulmonary hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1843.2006.00778.X

Effects of beraprost sodium, an oral prostacyclin analogue, in patients with pulmonary arterial hypertension: a randomized, double-blind, placebo-controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1843.2006.00778.X

A novel potent vasoconstrictor peptide produced by vascular endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1843.2006.00778.X

Expression of endothelin-1 in the lungs of patients with pulmonary hypertension.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1843.2006.00778.X

Endothelin and pulmonary hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1843.2006.00778.X

Effects of the dual endothelin-receptor antagonist bosentan in patients with pulmonary hypertension: a randomised placebo-controlled study

21 January 2018

1 reference

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Survival with first-line bosentan in patients with primary pulmonary hypertension.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1843.2006.00778.X

Sildenafil for pulmonary arterial hypertension: exciting, but protection required

21 January 2018

1 reference

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Pulmonary vasoconstriction and hypertension in mice with targeted disruption of the endothelial nitric oxide synthase (NOS 3) gene

21 January 2018

1 reference

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Reduced expression of endothelial nitric oxide synthase in the lungs of patients with pulmonary hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1843.2006.00778.X

Inhaled nitric oxide. A selective pulmonary vasodilator reversing hypoxic pulmonary vasoconstriction.

21 January 2018

1 reference

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Sildenafil versus Endothelin Receptor Antagonist for Pulmonary Hypertension (SERAPH) study

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1843.2006.00778.X

Oral sildenafil improves primary pulmonary hypertension refractory to epoprostenol

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1843.2006.00778.X

Combination therapy with oral sildenafil and inhaled iloprost for severe pulmonary hypertension.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1843.2006.00778.X

Pulmonary hypertension: inhaled nitric oxide, sildenafil and natriuretic peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1843.2006.00778.X

Lung transplantation for primary pulmonary hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1843.2006.00778.X

Atrial septostomy for pulmonary hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1843.2006.00778.X

The serotonin transporter: a vehicle to elucidate pulmonary hypertension?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1843.2006.00778.X

5-hydroxytryptamine and the pulmonary circulation: receptors, transporters and relevance to pulmonary arterial hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1843.2006.00778.X

Appetite-suppressant drugs and the risk of primary pulmonary hypertension. International Primary Pulmonary Hypertension Study Group

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1843.2006.00778.X

Increased plasma serotonin in primary pulmonary hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1843.2006.00778.X

Aminorex, fenfluramine, and chlorphentermine are serotonin transporter substrates. Implications for primary pulmonary hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1843.2006.00778.X

Evidence for 5-HT1-like receptor-mediated vasoconstriction in human pulmonary artery

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1843.2006.00778.X

5-Hydroxytryptamine receptors mediating vasoconstriction in pulmonary arteries from control and pulmonary hypertensive rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1843.2006.00778.X

Serotonin transporter inhibitors protect against hypoxic pulmonary hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1843.2006.00778.X

Overexpression of the 5-hydroxytryptamine transporter gene: effect on pulmonary hemodynamics and hypoxia-induced pulmonary hypertension.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1843.2006.00778.X

Serotonin transporter inhibition prevents and reverses monocrotaline-induced pulmonary hypertension in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1843.2006.00778.X

Function of the serotonin 5-hydroxytryptamine 2B receptor in pulmonary hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1843.2006.00778.X

Serotonin-induced smooth muscle hyperplasia in various forms of human pulmonary hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1843.2006.00778.X

Association of anxiety-related traits with a polymorphism in the serotonin transporter gene regulatory region

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1843.2006.00778.X

Polymorphism of the Serotonin Transporter Gene and Pulmonary Hypertension in Chronic Obstructive Pulmonary Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1843.2006.00778.X

Proliferation and signaling in fibroblasts: role of 5-hydroxytryptamine2A receptor and transporter

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1843.2006.00778.X

Hypoxic pulmonary vasoconstriction: role of ion channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1843.2006.00778.X

Receptor-operated Ca2(+)-permeable nonselective cation channels in vascular smooth muscle: a physiologic perspective

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1843.2006.00778.X

Preferential expression and function of voltage-gated, O2-sensitive K+ channels in resistance pulmonary arteries explains regional heterogeneity in hypoxic pulmonary vasoconstriction: ionic diversity in smooth muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1843.2006.00778.X

In vivo gene transfer of the O2-sensitive potassium channel Kv1.5 reduces pulmonary hypertension and restores hypoxic pulmonary vasoconstriction in chronically hypoxic rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1843.2006.00778.X

The pharmacology of dichloroacetate

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1843.2006.00778.X

Dichloroacetate, a metabolic modulator, prevents and reverses chronic hypoxic pulmonary hypertension in rats: role of increased expression and activity of voltage-gated potassium channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1843.2006.00778.X

Dichloroacetate prevents and reverses pulmonary hypertension by inducing pulmonary artery smooth muscle cell apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1843.2006.00778.X

Activation of K+ channels: an essential pathway in programmed cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1843.2006.00778.X

Efficacy of dichloroacetate as a lactate-lowering drug

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1843.2006.00778.X

Effects of statins on endothelium and endothelial progenitor cell recruitment

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1843.2006.00778.X

Attenuation of chronic hypoxic pulmonary hypertension by simvastatin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1843.2006.00778.X

Simvastatin attenuates smooth muscle neointimal proliferation and pulmonary hypertension in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1843.2006.00778.X

Simvastatin rescues rats from fatal pulmonary hypertension by inducing apoptosis of neointimal smooth muscle cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1843.2006.00778.X

Simvastatin treatment of pulmonary hypertension: an observational case series

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1843.2006.00778.X

Hypoxic pulmonary vasoconstriction

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1843.2006.00778.X

10.1111/J.1440-1843.2006.00778.X

21 January 2018

Identifiers

DOI

1 reference

13 August 2017

1 reference