(Q36375375)

English

Interleukin 2, but not other common gamma chain-binding cytokines, can reverse the defect in generation of CD4 effector T cells from naive T cells of aged mice

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scholarly article

1 reference

Europe PubMed Central

13 August 2017

Interleukin 2, but not other common gamma chain-binding cytokines, can reverse the defect in generation of CD4 effector T cells from naive T cells of aged mice (English)

1 reference

Europe PubMed Central

13 August 2017

0 references

author name string

L Haynes

1

1 reference

Europe PubMed Central

13 August 2017

P J Linton

2

1 reference

Europe PubMed Central

13 August 2017

S M Eaton

3

1 reference

Europe PubMed Central

13 August 2017

S L Tonkonogy

4

1 reference

Europe PubMed Central

13 August 2017

S L Swain

5

1 reference

Europe PubMed Central

13 August 2017

language of work or name

0 references

publication date

1 October 1999

1 reference

Europe PubMed Central

13 August 2017

Journal of Experimental Medicine

1 reference

Europe PubMed Central

13 August 2017

190

1 reference

Europe PubMed Central

13 August 2017

1013-1024

1 reference

Europe PubMed Central

13 August 2017

7

1 reference

Europe PubMed Central

13 August 2017

Helper T cell differentiation is controlled by the cell cycle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195647

30 September 2017

Distinct methylation of the interferon gamma (IFN-gamma) and interleukin 3 (IL-3) genes in newly activated primary CD8+ T lymphocytes: regional IFN-gamma promoter demethylation and mRNA expression are heritable in CD44(high)CD8+ T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195647

30 September 2017

Following the fate of individual T cells throughout activation and clonal expansion. Signals from T cell receptor and CD28 differentially regulate the induction and duration of a proliferative response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195647

30 September 2017

Unequal death in T helper cell (Th)1 and Th2 effectors: Th1, but not Th2, effectors undergo rapid Fas/FasL-mediated apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195647

30 September 2017

Antigen-independent changes in naive CD4 T cells with aging

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195647

30 September 2017

Autocrine feedback death and the regulation of mature T lymphocyte antigen responses.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195647

30 September 2017

From naive to memory T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195647

30 September 2017

Ulcerative colitis-like disease in mice with a disrupted interleukin-2 gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195647

30 September 2017

Control of CD4 effector fate: transforming growth factor beta 1 and interleukin 2 synergize to prevent apoptosis and promote effector expansion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195647

30 September 2017

Role of 4-1BB ligand in costimulation of T lymphocyte growth and its upregulation on M12 B lymphomas by cAMP.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195647

30 September 2017

Interleukin 2 (IL-2) augments transcription of the IL-2 receptor gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195647

30 September 2017

Interleukin 2 regulates its own receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195647

30 September 2017

Molecular events in the induction of a nonresponsive state in interleukin 2-producing helper T-lymphocyte clones

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195647

30 September 2017

Development and function of T cells in mice rendered interleukin-2 deficient by gene targeting

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195647

30 September 2017

CD48 is a counter-receptor for mouse CD2 and is involved in T cell activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195647

30 September 2017

Heat-stable antigen is a costimulatory molecule for CD4 T cell growth

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195647

30 September 2017

Age-related changes in CD4 T cells of T cell receptor transgenic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195647

30 September 2017

Costimulatory requirements of naive CD4+ T cells. ICAM-1 or B7-1 can costimulate naive CD4 T cell activation but both are required for optimum response.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195647

30 September 2017

Potent and selective stimulation of memory-phenotype CD8+ T cells in vivo by IL-15.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195647

28 June 2018

T cell clonal anergy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195647

28 June 2018

T cell stimulation in vivo by lipopolysaccharide (LPS).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195647

28 June 2018

Treatment of old mice with IL-2 corrects dysregulated IL-2 and IL-4 production

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195647

28 June 2018

Differential tyrosine-specific protein phosphorylation in mouse T lymphocyte subsets. Effect of age.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195647

28 June 2018

Flow cytometric determination of cytokines in activated murine T helper lymphocytes: expression of interleukin-10 in interferon-gamma and in interleukin-4-expressing cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195647

28 June 2018

Heterogeneity of intracellular cytokine synthesis at the single-cell level in polarized T helper 1 and T helper 2 populations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195647

28 June 2018

Establishment of mouse cell lines which constitutively secrete large quantities of interleukin 2, 3, 4 or 5, using modified cDNA expression vectors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195647

28 June 2018

Pgp-1hi T lymphocytes accumulate with age in mice and respond poorly to concanavalin A.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195647

28 June 2018

Age-related changes in lymphokine production related to a decreased number of CD45RBhi CD4+ T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195647

28 June 2018

Memory T lymphocyte hyporesponsiveness to non-cognate stimuli: a key factor in age-related immunodeficiency

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195647

28 June 2018

Differential age-change in the numbers of CD4+CD45RA+ and CD4+CD29+ T cell subsets in human peripheral blood

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195647

28 June 2018

Differential costimulatory effects of adhesion molecules B7, ICAM-1, LFA-3, and VCAM-1 on resting and antigen-primed CD4+ T lymphocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195647

28 June 2018

High antigen density and IL-2 are required for generation of CD4 effectors secreting Th1 rather than Th0 cytokines.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195647

21 September 2018

The interleukin 2 receptor alpha chain/CD25 promoter is a target for nuclear factor of activated T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195647

21 September 2018

The age-associated increase in IFN-gamma synthesis by mouse CD8+ T cells correlates with shifts in the frequencies of cell subsets defined by membrane CD44, CD45RB, 3G11, and MEL-14 expression.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195647

21 September 2018

Normal clonal expansion but impaired Fas-mediated cell death and anergy induction in interleukin-2-deficient mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195647

21 September 2018

Interleukin-2 programs mouse alpha beta T lymphocytes for apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195647

21 September 2018

CD28 engagement and proinflammatory cytokines contribute to T cell expansion and long-term survival in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195647

21 October 2018

Modulation of chromatin structure regulates cytokine gene expression during T cell differentiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/10510091

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional responses and apoptosis of CD25 (IL-2R alpha)-deficient T cells expressing a transgenic antigen receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/10510091

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lymphokines and aging: interleukin-2 production and activity in aged animals

1 reference

https://pubmed.ncbi.nlm.nih.gov/10510091

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

T lymphocytes of young and aged rats. II. Functional defects and the role of interleukin-2

1 reference

https://pubmed.ncbi.nlm.nih.gov/10510091

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Limiting dilution analysis of alloreactive cytotoxic precursor cells in aging mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/10510091

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanisms of age-related decline in antigen-specific T cell proliferative response: IL-2 receptor expression and recombinant IL-2 induced proliferative response of purified Tac-positive T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/10510091

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differences in the expression profiles of CD45RB, Pgp-1, and 3G11 membrane antigens and in the patterns of lymphokine secretion by splenic CD4+ T cells from young and aged mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/10510091

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Influence of age on the signal transduction of T cells in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/10510091

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Age-related alterations in the activation and expression of phosphotyrosine kinases and protein kinase C (PKC) among human B cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/10510091

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD27 is a signal-transducing molecule involved in CD45RA+ naive T cell costimulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/10510091

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD40 ligand induction on T cell subsets by peptide-presenting B cells: implications for development of the primary T and B cell response

1 reference

https://pubmed.ncbi.nlm.nih.gov/10510091

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

T cell growth cytokines cause the superinduction of molecules mediating antigen-induced T lymphocyte death

1 reference

https://pubmed.ncbi.nlm.nih.gov/10510091

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1084/JEM.190.7.1013

1 reference

Europe PubMed Central

13 August 2017

1 reference

Europe PubMed Central

13 August 2017

1 reference

Europe PubMed Central

13 August 2017

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