(Q36376548)

English

Oral but not parenteral interleukin (IL)-12 redirects T helper 2 (Th2)-type responses to an oral vaccine without altering mucosal IgA responses

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scholarly article

1 reference

Europe PubMed Central

13 August 2017

Oral but not parenteral interleukin (IL)-12 redirects T helper 2 (Th2)-type responses to an oral vaccine without altering mucosal IgA responses (English)

1 reference

Europe PubMed Central

13 August 2017

author name string

M Marinaro

1

1 reference

Europe PubMed Central

13 August 2017

P N Boyaka

2

1 reference

Europe PubMed Central

13 August 2017

F D Finkelman

3

1 reference

Europe PubMed Central

13 August 2017

H Kiyono

4

1 reference

Europe PubMed Central

13 August 2017

R J Jackson

5

1 reference

Europe PubMed Central

13 August 2017

E Jirillo

6

1 reference

Europe PubMed Central

13 August 2017

J R McGhee

7

1 reference

Europe PubMed Central

13 August 2017

language of work or name

0 references

publication date

1 February 1997

1 reference

Europe PubMed Central

13 August 2017

Journal of Experimental Medicine

1 reference

Europe PubMed Central

13 August 2017

185

1 reference

Europe PubMed Central

13 August 2017

3

1 reference

Europe PubMed Central

13 August 2017

415-427

1 reference

Europe PubMed Central

13 August 2017

Oral immunization of interleukin-4 (IL-4) knockout mice with a recombinant Salmonella strain or cholera toxin reveals that CD4+ Th2 cells producing IL-6 and IL-10 are associated with mucosal immunoglobulin A responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196042

30 September 2017

Optimizing oral vaccines: induction of systemic and mucosal B-cell and antibody responses to tetanus toxoid by use of cholera toxin as an adjuvant

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196042

30 September 2017

Interleukin 10 (IL-10) inhibits human lymphocyte interferon gamma-production by suppressing natural killer cell stimulatory factor/IL-12 synthesis in accessory cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196042

30 September 2017

Resolution of cutaneous leishmaniasis: interleukin 12 initiates a protective T helper type 1 immune response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196042

30 September 2017

Development of TH1 CD4+ T cells through IL-12 produced by Listeria-induced macrophages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196042

30 September 2017

Acquisition of lymphokine-producing phenotype by CD4+ T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196042

30 September 2017

Effects of interleukin 12 on immune responses and host protection in mice infected with intestinal nematode parasites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196042

30 September 2017

Interleukin 12 acts directly on CD4+ T cells to enhance priming for interferon gamma production and diminishes interleukin 4 inhibition of such priming

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196042

30 September 2017

Switch from a type 2 to a type 1 T helper cell response and cure of established Leishmania major infection in mice is induced by combined therapy with interleukin 12 and Pentostam

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196042

30 September 2017

Interleukin-12: a proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptive immunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196042

30 September 2017

Interleukin 10 induces B lymphocytes from IgA-deficient patients to secrete IgA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196042

30 September 2017

Preferential induction of polyclonal IgA secretion by murine Peyer's patch dendritic cell-T cell mixtures

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196042

30 September 2017

Interleukins and IgA synthesis. Human and murine interleukin 6 induce high rate IgA secretion in IgA-committed B cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196042

30 September 2017

TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196042

30 September 2017

Identification and purification of natural killer cell stimulatory factor (NKSF), a cytokine with multiple biologic effects on human lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196042

30 September 2017

IL-4 is required to generate and sustain in vivo IgE responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196042

30 September 2017

Lymphokine control of in vivo immunoglobulin isotype selection.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196042

30 September 2017

Role of cytokines in the differentiation of CD4+ T-cell subsets in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196042

30 September 2017

Cloning of cDNA for natural killer cell stimulatory factor, a heterodimeric cytokine with multiple biologic effects on T and natural killer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196042

30 September 2017

Induction of interferon gamma production by natural killer cell stimulatory factor: characterization of the responder cells and synergy with other inducers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196042

30 September 2017

Production of natural killer cell stimulatory factor (interleukin 12) by peripheral blood mononuclear cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196042

30 September 2017

Recombinant interleukin-12 suppresses the synthesis of immunoglobulin E by interleukin-4 stimulated human lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196042

30 September 2017

Cloning and expression of murine IL-12

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196042

30 September 2017

Response of human natural killer (NK) cells to NK cell stimulatory factor (NKSF): cytolytic activity and proliferation of NK cells are differentially regulated by NKSF

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196042

30 September 2017

Potential applications of liposomes to therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196042

30 September 2017

Oral administration of insulin by encapsulation within liposomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196042

30 September 2017

Hypoglycaemic effect of liposome-entrapped insulin administered intragastrically into rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196042

30 September 2017

Regulation of mucosal and systemic antibody responses by T helper cell subsets, macrophages, and derived cytokines following oral immunization with live recombinant Salmonella.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196042

28 June 2018

Helper T cell subsets for immunoglobulin A responses: oral immunization with tetanus toxoid and cholera toxin as adjuvant selectively induces Th2 cells in mucosa associated tissues

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196042

28 June 2018

The role of interleukin-6 in mucosal IgA antibody responses in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196042

28 June 2018

IL-12 induces the production of IFN-gamma by neonatal human CD4 T cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196042

28 June 2018

Natural killer cell stimulatory factor (interleukin 12 [IL-12]) induces T helper type 1 (Th1)-specific immune responses and inhibits the development of IL-4-producing Th cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196042

28 June 2018

Interleukin 12 induces stable priming for interferon gamma (IFN-gamma) production during differentiation of human T helper (Th) cells and transient IFN-gamma production in established Th2 cell clones

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196042

28 June 2018

Cytokine-enhanced NK cell-mediated cytotoxicity. Positive modulatory effects of IL-2 and IL-12 on stimulus-dependent granule exocytosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196042

28 June 2018

IFN-gamma induces IL-12 mRNA expression by a murine macrophage cell line, J774.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196042

28 June 2018

Interleukin 5 and interleukin 4 produced by Peyer's patch T cells selectively enhance immunoglobulin A expression.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196042

28 June 2018

In vitro measurement of antigen-specific cell-mediated immune responses using recombinant HIV-1 proteins adsorbed to latex microspheres.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196042

28 June 2018

Origin and fate of IgE-bearing lymphocytes. II. Gut-associated lymphoid tissue as sites of first appearance of IgE-bearing B lymphocytes and hapten-specific IgE antibody-forming cells in mice immunized with benzylpenicilloyl-keyhole limpet hemocyani

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196042

28 June 2018

Regulation of human cytolytic lymphocyte responses by interleukin-12

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196042

28 June 2018

Disruption of the murine IL-4 gene blocks Th2 cytokine responses.

1 reference

https://api.crossref.org/works/10.1084%2FJEM.185.3.415

21 January 2018

Mucosal immunity to infection with implications for vaccine development

1 reference

https://api.crossref.org/works/10.1084%2FJEM.185.3.415

21 January 2018

Suppression of relapsing experimental autoimmune encephalomyelitis in the SJL/J mouse by oral administration of type I interferons

1 reference

https://api.crossref.org/works/10.1084%2FJEM.185.3.415

21 January 2018

Restoration of HIV-specific cell-mediated immune responses by interleukin-12 in vitro

1 reference

https://api.crossref.org/works/10.1084%2FJEM.185.3.415

21 January 2018

An IL-12-based vaccination method for preventing fibrosis induced by schistosome infection

1 reference

https://api.crossref.org/works/10.1084%2FJEM.185.3.415

21 January 2018

An activated murine B cell lymphoma line (A-20) produces a factor-like activity which is functionally related to human natural killer cell stimulatory factor

1 reference

https://api.crossref.org/works/10.1084%2FJEM.185.3.415

21 January 2018

Interleukin-12 profoundly up-regulates the synthesis of antigen-specific complement-fixing IgG2a, IgG2b and IgG3 antibody subclasses in vivo

1 reference

https://api.crossref.org/works/10.1084%2FJEM.185.3.415

21 January 2018

Interleukin 12 alters the isotype-restricted antibody response of mice to hen eggwhite lysozyme

1 reference

https://api.crossref.org/works/10.1084%2FJEM.185.3.415

21 January 2018

Impaired mucosal immune responses in interleukin 4-targeted mice

1 reference

https://api.crossref.org/works/10.1084%2FJEM.185.3.415

21 January 2018

Helper Th1 and Th2 cell responses following mucosal or systemic immunization with cholera toxin

1 reference

https://api.crossref.org/works/10.1084%2FJEM.185.3.415

21 January 2018

The gastrointestinal absorption of liposomally entrapped insulin in normal rats [proceedings]

1 reference

https://api.crossref.org/works/10.1084%2FJEM.185.3.415

21 January 2018

Effect of oral beta interferon on subsequent immune responsiveness

1 reference

https://api.crossref.org/works/10.1084%2FJEM.185.3.415

21 January 2018

Stability of liposomes in vitro and their uptake by rat Peyer's patches following oral administration

1 reference

https://api.crossref.org/works/10.1084%2FJEM.185.3.415

21 January 2018

Dendritic cells support production of IgA and other non-IgM isotypes in clonal microculture

1 reference

https://api.crossref.org/works/10.1084%2FJEM.185.3.415

21 January 2018

Effects of IL-12 on helper T cell-dependent immune responses in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/9053442

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cellular and molecular mechanisms of the IL-12-induced increase in allospecific murine cytolytic T cell activity. Implications for the age-related decline in CTL

1 reference

https://pubmed.ncbi.nlm.nih.gov/9053442

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Second signal activity of IL-12 on the proliferation and IL-2R expression of T helper cell-1 clone

1 reference

https://pubmed.ncbi.nlm.nih.gov/9053442

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Production of IgE antibody and allergic sensitization of intestinal and peripheral tissues after oral immunization with protein Ag and cholera toxin

1 reference

https://pubmed.ncbi.nlm.nih.gov/9053442

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mucosal adjuvant effect of cholera toxin in mice results from induction of T helper 2 (Th2) cells and IL-4

1 reference

https://pubmed.ncbi.nlm.nih.gov/9053442

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Recombinant murine IL-5 induces high rate IgA synthesis in cycling IgA-positive Peyer's patch B cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/9053442

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oral use of human alpha interferon in cats

1 reference

https://pubmed.ncbi.nlm.nih.gov/9053442

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ultrastructural study of liposome uptake by M cells of rat Peyer's patch: an oral vaccine system for delivery of purified antigen

1 reference

https://pubmed.ncbi.nlm.nih.gov/9053442

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of IL-12 on in vivo cytokine gene expression and Ig isotype selection

1 reference

https://pubmed.ncbi.nlm.nih.gov/9053442

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1084/JEM.185.3.415

1 reference

Europe PubMed Central

13 August 2017

release_c6g4upzsdbfcjcm6dueueszkbm

1 reference

https://api.fatcat.wiki/v0/release/c6g4upzsdbfcjcm6dueueszkbm

24 November 2022

based on heuristic

mapped directly with Wikidata item

1 reference

Europe PubMed Central

13 August 2017

1 reference

Europe PubMed Central

13 August 2017

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