(Q36377030)

English

Controlled proteolysis of the multifunctional protein that initiates pyrimidine biosynthesis in mammalian cells: evidence for discrete structural domains

scientific article published on November 1, 1981

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Controlled proteolysis of the multifunctional protein that initiates pyrimidine biosynthesis in mammalian cells: evidence for discrete structural domains (English)

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

1 reference

based on heuristic

inferred from title

author name string

M. I. Mally

1

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A6118866

8 August 2023

D. R. Grayson

2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A6118866

8 August 2023

D. R. Evans

3

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A6118866

8 August 2023

language of work or name

0 references

publication date

1 November 1981

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

full work available at URL

https://europepmc.org/articles/PMC349106

online access status

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Europe PubMed Central

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A6118866

8 August 2023

https://europepmc.org/articles/PMC349106?pdf=render

Portable Document Format

online access status

content deliverer

Europe PubMed Central

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A6118866

8 August 2023

https://pnas.org/doi/pdf/10.1073/pnas.78.11.6647

1 reference

10.1073/PNAS.78.11.6647

https://api.crossref.org/works/10.1073/PNAS.78.11.6647

8 August 2023

Proceedings of the National Academy of Sciences of the United States of America

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

78

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

11

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

6647-6651

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=349106

30 September 2017

Aggregation states and catalytic properties of the multienzyme complex catalyzing the initial steps of pyrimidine biosynthesis in rat liver

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=349106

30 September 2017

Multifunctional proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=349106

30 September 2017

Gene amplification causes overproduction of the first three enzymes of UMP synthesis in N-(phosphonacetyl)-L-aspartate-resistant hamster cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=349106

30 September 2017

Purification of homogeneous glutamine-dependent carbamyl phosphate synthetase from ascites hepatoma cells as a complex with aspartate transcarbamylase and dihydroorotase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=349106

30 September 2017

Reversible dissociation of a carbamoyl phosphate synthase-aspartate transcarbamoylase-dihydroorotase complex from ovarian eggs of Rana catesbeiana: effect of uridine triphosphate and other modifiers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=349106

30 September 2017

Biochemical genetic analysis of pyrimidine biosynthesis in mammalian cells: III. Association of carbamyl phosphate synthetase, aspartate transcarbamylase, and dihydroorotase in mutants of cultured Chinese hamster cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=349106

30 September 2017

Alteration in structure of multifunctional protein from Chinese hamster ovary cells defective in pyrimidine biosynthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=349106

30 September 2017

Purification of Aspartate Transcabamylase from Drosophila melanogaster

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=349106

30 September 2017

Multi-Enzyme Complex of Glutamine-Dependent Carbamoyl-Phosphate Synthetase with Aspartate Carbamoyltransferase and Dihydroorotase from Rat Ascites-Hepatoma Cells. Purification, Molecular Properties and Limited Proteolysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=349106

30 September 2017

Purification from hamster cells of the multifunctional protein that initiates de novo synthesis of pyrimidine nucleotides

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=349106

30 September 2017

Stable mutants of mammalian cells that overproduce the first three enzymes of pyrimidine nucleotide biosynthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=349106

30 September 2017

Isolation of a multifunctional complex containing the first three enzymes of pyrimidine biosynthesis inDrosophila melanogaster

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=349106

30 September 2017

The overall synthesis of L-5,6-dihydroorotate by multienzymatic protein pyr1-3 from hamster cells. Kinetic studies, substrate channeling, and the effects of inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=349106

28 June 2018

Catalytic synergy in the multifunctional protein that initiates pyrimidine biosynthesis in Syrian hamster cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=349106

28 June 2018

Copurification of carbamoyl phosphate synthetase and aspartate transcarbamoylase from mouse spleen

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=349106

28 June 2018

Regulation of activity of carbamoyl phosphate synthetase from mouse spleen

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=349106

28 June 2018

N-(phosphonacetyl)-L-aspartate, a potent transition state analog inhibitor of aspartate transcarbamylase, blocks proliferation of mammalian cells in culture.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=349106

28 June 2018

N-(Phosphonacetyl)-L-aspartate-resistant hamster cells overaccumulate a single mRNA coding for the multifunctional protein that catalyzes the first steps of UMP synthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=349106

28 June 2018

Selective Inactivation of the Glutamine Binding Site of Escherichia coli Carbamyl Phosphate Synthetase by 2-Amino-4-oxo-5-chloropentanoic Acid*

1 reference

https://pubmed.ncbi.nlm.nih.gov/6118866

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Organization of a multifunctional protein in pyrimidine biosynthesis. Analyses of active, tryptic fragments

1 reference

https://pubmed.ncbi.nlm.nih.gov/6118866

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Control of pyrimidine biosynthesis in mammalian tissues. I. Partial purification and characterization of glutamine-utilizing carbamyl phosphate synthetase of mouse spleen and its tissue distribution

1 reference

https://pubmed.ncbi.nlm.nih.gov/6118866

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Initial steps in pyrimidine synthesis in Ehrlich ascites carcinoma in vitro. II. The synthesis of carbamyl phosphate by a soluble, glutamine-dependent carbamyl phosphate synthetase

1 reference

https://pubmed.ncbi.nlm.nih.gov/6118866

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A Glutamine-dependent Enzyme for the Synthesis of Carbamyl Phosphate for Pyrimidine Biosynthesis in Fetal Rat Liver

1 reference

https://pubmed.ncbi.nlm.nih.gov/6118866

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Initial steps in pyrimidine synthesis in ehrlich ascites carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/6118866

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation by 5-phosphoribosyl 1-pyrophosphate of glutamine-dependent carbamyl phosphate synthetase from mouse spleen

1 reference

https://pubmed.ncbi.nlm.nih.gov/6118866

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Control of pyrimidine biosynthesis in human lymphocytes. Simultaneous increase in activities of glutamine-utilizing carbamyl phosphate synthetase and aspartate transcarbamylase in phytohemagglutinin-stimulated human peripheral lymphocytes and their

1 reference

https://pubmed.ncbi.nlm.nih.gov/6118866

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Uridylic acid synthesis in Ehrlich ascites carcinoma. Properties, subcellular distribution, and nature of enzyme complexes of the six biosynthetic enzymes

1 reference

https://pubmed.ncbi.nlm.nih.gov/6118866

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dissociation by elastase digestion of enzyme complex catalyzing the initial steps of pyrimidine biosynthesis in rat liver

1 reference

https://pubmed.ncbi.nlm.nih.gov/6118866

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tables for estimating sedimentation through linear concentration gradients of sucrose solution

1 reference

https://pubmed.ncbi.nlm.nih.gov/6118866

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1073/PNAS.78.11.6647

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

1981PNAS...78.6647M

0 references

release_aqv66r46tbclvhp7fkwzocwuri

1 reference

https://api.fatcat.wiki/v0/release/aqv66r46tbclvhp7fkwzocwuri

24 November 2022

based on heuristic

mapped directly with Wikidata item

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

ResearchGate publication ID

0 references

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