(Q36378971)

English

Compound I is the reactive intermediate in the first monooxygenation step during conversion of cholesterol to pregnenolone by cytochrome P450scc: EPR/ENDOR/cryoreduction/annealing studies

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Compound I is the reactive intermediate in the first monooxygenation step during conversion of cholesterol to pregnenolone by cytochrome P450scc: EPR/ENDOR/cryoreduction/annealing studies (English)

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

author name string

Roman Davydov

1

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Andrey A Gilep

2

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Natallia V Strushkevich

3

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Sergey A Usanov

4

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Brian M Hoffman

5

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

language of work or name

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publication date

5 October 2012

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Journal of the American Chemical Society

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

134

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

41

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

17149-17156

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Structural basis for pregnenolone biosynthesis by the mitochondrial monooxygenase system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491644

30 September 2017

Structural Basis for Three-step Sequential Catalysis by the Cholesterol Side Chain Cleavage Enzyme CYP11A1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491644

30 September 2017

Cytochrome P450 compound I: capture, characterization, and C-H bond activation kinetics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491644

30 September 2017

Active intermediates in heme monooxygenase reactions as revealed by cryoreduction/annealing, EPR/ENDOR studies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491644

30 September 2017

At the crossroads of steroid hormone biosynthesis: the role, substrate specificity and evolutionary development of CYP17.

1 reference

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30 September 2017

The mystery of cytochrome P450 Compound I: a mini-review dedicated to Klaus Ruckpaul

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491644

30 September 2017

Spectroscopic studies of the oxidation of ferric CYP153A6 by peracids: Insights into P450 higher oxidation states

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491644

30 September 2017

EPR and ENDOR characterization of the reactive intermediates in the generation of NO by cryoreduced oxy-nitric oxide synthase from Geobacillus stearothermophilus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491644

30 September 2017

The critical iron-oxygen intermediate in human aromatase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491644

30 September 2017

Structure and quantum chemical characterization of chloroperoxidase compound 0, a common reaction intermediate of diverse heme enzymes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491644

30 September 2017

Structure and chemistry of cytochrome P450.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491644

30 September 2017

Progesterone synthesis by the human placenta

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491644

30 September 2017

Models and mechanisms of O-O bond activation by cytochrome P450. A critical assessment of the potential role of multiple active intermediates in oxidative catalysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491644

30 September 2017

Oxidizing species in the mechanism of cytochrome P450.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491644

30 September 2017

Adrenodoxin-cytochrome P450scc interaction as revealed by EPR spectroscopy: comparison with the putidaredoxin-cytochrome P450cam system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491644

30 September 2017

The catalytic pathway of cytochrome p450cam at atomic resolution

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491644

30 September 2017

Mechanistic studies on aromatase and related C-C bond cleaving P-450 enzymes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491644

30 September 2017

Steroid binding properties of beef adrenal cortical cytochrome P-450 which catalyzes the conversion of cholesterol into pregnenolone

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491644

30 September 2017

Probing the oxyferrous and catalytically active ferryl states of Amphitrite ornata dehaloperoxidase by cryoreduction and EPR/ENDOR spectroscopy. Detection of compound I.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491644

28 June 2018

Probing the ternary complexes of indoleamine and tryptophan 2,3-dioxygenases by cryoreduction EPR and ENDOR spectroscopy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491644

28 June 2018

The oxyferro complex of adrenal cytochrome P-450scc. Effect of cholesterol and intermediates on its stability and optical characteristics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491644

28 June 2018

On the role of water in peroxidase catalysis: a theoretical investigation of HRP compound I formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491644

21 September 2018

Heme oxygenase reveals its strategy for catalyzing three successive oxygenation reactions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491644

21 September 2018

Characterization of the microsomal cytochrome P450 2B4 O2 activation intermediates by cryoreduction and electron paramagnetic resonance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491644

21 September 2018

Structural studies of constitutive nitric oxide synthases with diatomic ligands bound

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491644

21 September 2018

Substrate modulation of the properties and reactivity of the oxy-ferrous and hydroperoxo-ferric intermediates of cytochrome P450cam as shown by cryoreduction-EPR/ENDOR spectroscopy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491644

21 September 2018

Proton transfer at helium temperatures during dioxygen activation by heme monooxygenases.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491644

21 September 2018

Conformational substates of the oxyheme centers in alpha and beta subunits of hemoglobin as disclosed by EPR and ENDOR studies of cryoreduced protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491644

21 September 2018

A superoxo-ferrous state in a reduced oxy-ferrous hemoprotein and model compounds

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491644

21 September 2018

Catalytic mechanism of heme oxygenase through EPR and ENDOR of cryoreduced oxy-heme oxygenase and its Asp 140 mutants

1 reference

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21 September 2018

Proton-transfer dynamics in the activation of cytochrome P450eryF.

1 reference

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21 September 2018

Kinetic characterization of compound I formation in the thermostable cytochrome P450 CYP119.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491644

21 September 2018

Hydroxylation of camphor by reduced oxy-cytochrome P450cam: mechanistic implications of EPR and ENDOR studies of catalytic intermediates in native and mutant enzymes

1 reference

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21 September 2018

Water (in Water) as an Intrinsically Efficient Proton Acceptor in Concerted Proton Electron Transfers

1 reference

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5 December 2018

Compound I of Nitric Oxide Synthase: The Active Site Protonation State

1 reference

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5 December 2018

New Features in the Catalytic Cycle of Cytochrome P450 during the Formation of Compound I from Compound 0

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491644

5 December 2018

Conformational dynamics and molecular interaction reactions of recombinant cytochrome p450scc (CYP11A1) detected by fluorescence energy transfer

1 reference

https://pubmed.ncbi.nlm.nih.gov/23039857

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Electron paramagnetic resonance detectable states of cytochrome P-450cam

1 reference

https://pubmed.ncbi.nlm.nih.gov/23039857

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparative structural and immunochemical characterization of recombinant and natural cytochrome p450scc (CYPXIAI)

1 reference

https://pubmed.ncbi.nlm.nih.gov/23039857

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1021/JA3067226

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

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