(Q36379273)

13 August 2017

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title

Tracers for metabolic imaging of brain and heart. Radiochemistry and radiopharmacology (English)

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13 August 2017

G Stöcklin

1

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13 August 2017

publication date

1 January 1992

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13 August 2017

number of pages

25

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European Journal of Nuclear Medicine and Molecular Imaging

inferred from page(s)

published in

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13 August 2017

volume

19

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13 August 2017

issue

7

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13 August 2017

page(s)

527-551

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Radiosynthesis of a selective dopamine D-1 receptor antagonist: R(+)-7-chloro-8-hydroxy-3-[11C]methyl-1-phenyl-2,3,4,5-tetrahydro-1H-3 -benzazepine ([11C]SCH 23390)

13 August 2017

cites work

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12 December 2020

Synthesis and biodistribution of 123I N-(2-aminoethyl)-5-iodo-2-pyridinecarboxamide (Ro 43-0463), a monoamine oxidase B inhibitor

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12 December 2020

Efficient stereospecific synthesis of no-carrier-added 2-[18F]-fluoro-2-deoxy-D-glucose using aminopolyether supported nucleophilic substitution

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12 December 2020

Benzodiazepine receptors and cerebral blood flow in partial epilepsy

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12 December 2020

Metabolism of beta-methyl[1-11C]heptadecanoic acid in canine myocardium

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12 December 2020

No-carrier-added 3-(2'-[18F]fluoroethyl)spiperone, a new dopamine receptor-binding tracer for positron emission tomography

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12 December 2020

An improved synthesis of (3-N-[11C]methyl)spiperone

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12 December 2020

Radiolabeled hypoxic cell sensitizers: tracers for assessment of ischemia.

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12 December 2020

In vitro and in vivo evaluation of [123I]IBZM: a potential CNS D-2 dopamine receptor imaging agent

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12 December 2020

Radiolabeled adrenergi neuron-blocking agents: adrenomedullary imaging with [131I]iodobenzylguanidine

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12 December 2020

Imaging opiate receptors in the human brain by positron tomography

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12 December 2020

Radioiodinated 2'-iodospiperone: a new radioligand for in vivo dopamine receptor study

1 reference

12 December 2020

Synthesis and evaluation of radioiodinated terminal p-iodophenyl-substituted alpha- and beta-methyl-branched fatty acids

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12 December 2020

Regional myocardial free fatty acid extraction in normal and ischemic myocardium.

1 reference

12 December 2020

11C-SCH 39166, a selective ligand for visualization of dopamine-D1 receptor binding in the monkey brain using PET

1 reference

12 December 2020

Synthesis and preliminary evaluation of carbon-11-meta-hydroxyephedrine: a false transmitter agent for heart neuronal imaging

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12 December 2020

Radiosynthesis of an opiate receptor binding radiotracer: [11C]carfentanil.

1 reference

12 December 2020

The effects of carbidopa on the metabolism of 6-[18F]fluoro-L-dopa in rats, monkeys and humans

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12 December 2020

Mu-opiate receptors measured by positron emission tomography are increased in temporal lobe epilepsy

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12 December 2020

Myocardial emission computed tomography with iodine-123-labeled beta-methyl-branched fatty acid in patients with hypertrophic cardiomyopathy

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12 December 2020

Metabolic studies with L-[1-14C]tyrosine for the investigation of a kinetic model to measure protein synthesis rates with PET.

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12 December 2020

Synthesis of (R)-(-)- and (S)-(+)-4-fluorodeprenyl and (R)-(-)- and (S)-(+)-[N-11C-methyl]-4-fluorodeprenyl and positron emission tomography studies in baboon brain

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12 December 2020

[18F]-N-Methylspiroperidol: the radioligand of choice for PETT studies of the dopamine receptor in human brain

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12 December 2020

Increased amino acid transport into brain tumors measured by PET of L-(2-18F)fluorotyrosine

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12 December 2020

Cerebral metabolism of 6-[18F]fluoro-L-3,4-dihydroxyphenylalanine in the primate

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12 December 2020

In vivo [3H]spiperone binding: evidence for accumulation in corpus striatum by agonist-mediated receptor internalization

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12 December 2020

Dopamine D2 Receptor Imaging with SPECT: Studies in Different Neuropsychiatric Disorders

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12 December 2020

Mouse brain distribution of a carbon-11 labeled vesamicol derivative: presynaptic marker of cholinergic neurons

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12 December 2020

76Br-bromospiroperidol: A new tool for quantitative in-vivo imaging of neuroleptic receptors

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12 December 2020

In vivo study of central serotoninergic receptors in man using positron tomography

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12 December 2020

Brain dopamine metabolism in patients with Parkinson's disease measured with positron emission tomography

1 reference

12 December 2020

SPECT studies of brain tumors with L-3-[123I] iodo-alpha-methyl tyrosine: comparison with PET, 124IMT and first clinical results

1 reference

12 December 2020

Synthesis and biological evaluation of [125I]- and [123I]-4-iododexetimide, a potent muscarinic cholinergic receptor antagonist

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12 December 2020

Measurement of human cerebral monoamine oxidase type B (MAO-B) activity with positron emission tomography (PET): a dose ranging study with the reversible inhibitor Ro 19-6327

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12 December 2020

Synthesis and biodistribution of 18F-labeled fluoronitroimidazoles: potential in vivo markers of hypoxic tissue

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12 December 2020

Iodophenylpentadecanoic acid-myocardial blood flow relationship during maximal exercise with coronary occlusion

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12 December 2020

Noninvasive evaluation of sympathetic nervous system in human heart by positron emission tomography

1 reference

12 December 2020

Positron labeled muscarinic acetylcholine receptor antagonist: 2- and 4-[18F]fluorodexetimide. Syntheses and biodistribution

1 reference

12 December 2020

Synthesis of high specific activity (+)- and (-)-6-[18F]fluoronorepinephrine via the nucleophilic aromatic substitution reaction

1 reference

12 December 2020

A new route for the synthesis of [18F]fluoroaromatic substituted amino acids: no carrier added L-p-[18F]fluorophenylalanine

1 reference

12 December 2020

Positron emission tomography in assessment of regional stereospecificity of drugs

1 reference

12 December 2020

Beta-methyl[1-11C]heptadecanoic acid: a new myocardial metabolic tracer for positron emission tomography.

1 reference

12 December 2020

Comparison of L-[1-11C]methionine and L-methyl-[11C]methionine for measuring in vivo protein synthesis rates with PET

1 reference

12 December 2020

[123I]-2 beta-carbomethoxy-3 beta-(4-iodophenyl)tropane: high-affinity SPECT radiotracer of monoamine reuptake sites in brain

1 reference

12 December 2020

Potential antipsychotic agents. 9. Synthesis and stereoselective dopamine D-2 receptor blockade of a potent class of substituted (R)-N-[(1-benzyl-2-pyrrolidinyl)methyl]benzamides. Relations to other side chain congeners

1 reference

12 December 2020

In vitro and in vivo characterization of 4-[125I]iododexetimide binding to muscarinic cholinergic receptors in the rat heart

1 reference

12 December 2020

Evaluation of quaternized and neutral muscarinic receptor ligands in normal and DES-treated rat

1 reference

12 December 2020

A strategy for the study of cerebral amino acid transport using iodine-123-labeled amino acid radiopharmaceutical: 3-iodo-alpha-methyl-L-tyrosine

1 reference

12 December 2020

Central serotonergic S2 binding in Papio anubis measured in vivo with N-omega-[18F]fluoroethylketanserin and PET.

1 reference

12 December 2020

3-N-(2-[18F]-fluoroethyl)-spiperone: a novel ligand for cerebral dopamine receptor studies with pet

1 reference

12 December 2020

Biodistribution and radiation dosimetry of radioiodinated-SCH 23982, a potential dopamine D-1 receptor imaging agent

1 reference

12 December 2020

Effects of inhibition of fatty acid oxidation on myocardial kinetics of 11C-labeled palmitate

1 reference

12 December 2020

Production of 6-[18F]fluoro-l-DOPA and its metabolism in vivo—a critical review

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12 December 2020

Structurally modified fatty acids: clinical potential as tracers of metabolism

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12 December 2020

Preparation of 11C-labelled SCH 23390 for the in vivo study of dopamine D-1 receptors using positron emission tomography

1 reference

12 December 2020

Dopamine visualized in the basal ganglia of living man.

1 reference

12 December 2020

Preparation of [1-11C]acetate--an agent for the study of myocardial metabolism by positron emission tomography

1 reference

12 December 2020

Metabolic fate of radioiodinated heptadecanoic acid in the normal canine heart

1 reference

12 December 2020

C-11 palmitate for the noninvasive evaluation of regional myocardial fatty acid metabolism with positron computed tomography. III. In vivo demonstration of the effects of substrate availability on myocardial metabolism

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12 December 2020

Synthesis and evaluation of radioiodinated derivatives of 1-azabicyclo[2.2.2]oct-3-yl alpha-hydroxy-alpha-(4-iodophenyl)-alpha- phenylacetate as potential radiopharmaceuticals

1 reference

12 December 2020

Imaging dopamine receptors in the human brain by positron tomography

1 reference

12 December 2020

Omega-halofatty acids: a probe for mitochondrial membrane integrity. In vitro investigations in normal and ischaemic myocardium

1 reference

12 December 2020

The nigrostriatal dopaminergic system assessed in vivo by positron emission tomography in healthy volunteer subjects and patients with Parkinson's disease

1 reference

12 December 2020

The estimated density of D2 striatal receptors in schizophrenia. A study with positron emission tomography and 76Br-bromolisuride

1 reference

12 December 2020

Remote, semiautomated production of 6-[18F]fluoro-L-dopa for human studies with PET.

1 reference

12 December 2020

Carbon-11 labelling of eticlopride in two different positions--a selective high-affinity ligand for the study of dopamine D-2 receptors using PET

1 reference

12 December 2020

Brain and brain tumor uptake of L-3-[123I]iodo-alpha-methyl tyrosine: competition with natural L-amino acids

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12 December 2020

Amino acids for the measurement of protein synthesis in vivo by PET

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12 December 2020

Efflux of metabolized and nonmetabolized fatty acid from canine myocardium. Implications for quantifying myocardial metabolism tomographically

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12 December 2020

In vitro binding properties and autoradiographic imaging of 3-iodobenzamide ([125I]-IBZM): a potential imaging ligand for D-2 dopamine receptors in SPECT.

1 reference

12 December 2020

11C-labelling of Ro 15-1788 in two different positions, and also 11C-labelling of its main metabolite Ro 15-3890, for PET studies of benzodiazepine receptors

1 reference

12 December 2020

The preparation of fluorine-18 labelled radiopharmaceuticals

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12 December 2020

Myocardial imaging and metabolic studies with [17-123I]iodoheptadecanoic acid

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12 December 2020

Routine determination of [18F]-L-6-fluorodopa and its metabolites in blood plasma is essential for accurate positron emission tomography studies

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12 December 2020

Comparison in animal models of 18F-spiroperidol and 18F-haloperidol: potential agents for imaging the dopamine receptor

1 reference

12 December 2020

Mapping human brain monoamine oxidase A and B with 11C-labeled suicide inactivators and PET

1 reference

12 December 2020

Turnover of brain monoamine oxidase measured in vivo by positron emission tomography using L-[11C]deprenyl

1 reference

12 December 2020

In vivo and in vitro characteristics of the N-methyl derivative of [125I]3-quinuclidinyl 4-iodobenzilate

1 reference

12 December 2020

Copper-62-labeled pyruvaldehyde bis(N4-methylthiosemicarbazonato)copper(II): synthesis and evaluation as a positron emission tomography tracer for cerebral and myocardial perfusion.

1 reference

12 December 2020

Selective, irreversible in vivo binding of [11C]clorgyline and [11C]-L-deprenyl in mice: potential for measurement of functional monoamine oxidase activity in brain using positron emission tomography

1 reference

12 December 2020

Muscarinic acetylcholine receptors in Alzheimer's disease. In vivo imaging with iodine 123-labeled 3-quinuclidinyl-4-iodobenzilate and emission tomography

1 reference

12 December 2020

Cardiac beta-adrenergic receptor density measured in vivo using PET, CGP 12177, and a new graphical method.

1 reference

12 December 2020

Kinetics of in vivo binding of antagonist to muscarinic cholinergic receptor in the human heart studied by positron emission tomography

1 reference

12 December 2020

Characterization of radiolabeled fluoromisonidazole as a probe for hypoxic cells

1 reference

12 December 2020

[Amino acid uptake in brain tumors using positron emission tomography as an indicator for evaluating metabolic activity and malignancy]

1 reference

12 December 2020

Kinetics and displacement of [11C]RO 15-1788, a benzodiazepine antagonist, studied in human brain in vivo by positron tomography.

1 reference

12 December 2020

Biochemical concept and synthesis of a radioiodinated phenylfatty acid for in vivo metabolic studies of the myocardium

1 reference

12 December 2020

Imaging of brain tumors with L-3-[123I]iodo-alpha-methyl tyrosine and SPECT.

1 reference

12 December 2020

Duration of occupancy of opiate receptors by naltrexone

1 reference

12 December 2020

15-(p[75Br]bromophenyl)pentadecanoic acid: pharmacokinetics and potential as heart agent.

1 reference

12 December 2020

Tracer kinetics of 15-(ortho-123/131I-phenyl)-pentadecanoic acid (oPPA) and 15-(para-123/131I-phenyl)-pentadecanoic acid (pPPA) in animals and man

1 reference

12 December 2020

Tyrosine hydroxylase inhibitors.

1 reference

12 December 2020

The metabolism of [18F]6-fluoro-L-3,4-dihydroxyphenylalanine in the hooded rat.

1 reference

12 December 2020

New, potent cocaine analogs: ligand binding and transport studies in rat striatum

1 reference

12 December 2020

PET study of methionine accumulation in glioma and normal brain tissue: competition with branched chain amino acids.

1 reference

12 December 2020

Asymmetric synthesis of a precursor for the automated radiosynthesis of S-(3'-t-butylamino-2'-hydroxypropoxy)-benzimidazol-2-[11C]one (S-[11C]CGP 12177) as a preferred radioligand for beta-adrenergic receptors

1 reference

12 December 2020

In vivo characterization of myocardium muscarinic receptors by positron emission tomography

1 reference

12 December 2020

Noninvasive quantitation of regional myocardial oxygen consumption in vivo with [1-11C]acetate and dynamic positron emission tomography

1 reference

12 December 2020

The clinical role of metabolic imaging of the heart by positron emission tomography.

1 reference

12 December 2020

Regional cerebral opioid receptor studies with [11C]diprenorphine in normal volunteers

1 reference

12 December 2020

4-[18F]fluoro-L-m-tyrosine: an L-3,4-dihydroxyphenylalanine analog for probing presynaptic dopaminergic function with positron emission tomography

1 reference

12 December 2020

Fluorine-18-altanserin: a radioligand for the study of serotonin receptors with PET: radiolabeling and in vivo biologic behavior in rats

1 reference

12 December 2020

PET radioligands for dopamine receptors and re-uptake sites: chemistry and biochemistry

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12 December 2020

Cerebral muscarinic receptors in primary degenerative dementia as evaluated by SPECT with iodine-123-labeled QNB.

1 reference

12 December 2020

In-vivo demonstration of reduced benzodiazepine receptor binding in human epileptic foci

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12 December 2020

Accumulation of radioiodinated tyrosine derivatives in the adrenal medulla and in melanomas

1 reference

12 December 2020

Long-chain F-18 fatty acids for the study of regional metabolism in heart and liver; odd-even effects of metabolism in mice

1 reference

12 December 2020

Accumulation of radioiodinated L-alpha-methyltyrosine in pancreas of mice: concise communication

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12 December 2020

PET analysis of human dopamine receptor subtypes using 11C-SCH 23390 and 11C-raclopride

1 reference

12 December 2020

Neuronal mapping of the heart with 6-[18F]fluorometaraminol

1 reference

12 December 2020

Biochemical and autoradiographic study of cerebral protein synthesis with [18F]-and [14C]fluorophenylalanine

1 reference

12 December 2020

Routine synthesis of L-[18F]6-fluorodopa with fluorine-18 acetyl hypofluorite

1 reference

12 December 2020

Preparation and biodistribution of [125I]IBZM: a potential CNS D-2 dopamine receptor imaging agent

1 reference

12 December 2020

Radiopharmaceuticals for studying cardiac metabolism

1 reference

12 December 2020

New fast preparation of 123I labelled radiopharmaceuticals

1 reference

12 December 2020

11C-Ro15-1788 and 11C-flunitrazepam, two coordinates for the study by positron emission tomography of benzodiazepine binding sites

1 reference

12 December 2020

Radiopharmaceuticals. 12. A new rapid synthesis of carbon-11 labeled norepinephrine hydrochloride.

1 reference

12 December 2020

Kinetics of in vitro decarboxylation and the in vivo metabolism of 2-18F- and 6-18F-fluorodopa in the hooded rat.

1 reference

12 December 2020

Single photon emission tomography imaging of myocardial oxidative metabolism with 15-(p-[123I]iodophenyl) pentadecanoic acid in patients with coronary artery disease and aorto-coronary bypass graft surgery

1 reference

12 December 2020

Cerebral metabolism of L-[2-18F]fluorotyrosine, a new PET tracer of protein synthesis

1 reference

12 December 2020

Altered metabolism of [18F]-6-fluorodopa in the hooded rat following inhibition of catechol-O-methyltransferase with U-0521.

1 reference

12 December 2020

Carbon-11 labelled tyrosine to study tumor metabolism by positron emission tomography (PET)

1 reference

12 December 2020

New radioiodinated methyl-branched fatty acids for cardiac studies.

1 reference

12 December 2020

Determination of plasma [18F]-6-fluorodopa during positron emission tomography: elimination and metabolism in carbidopa treated subjects

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12 December 2020

A radiosynthesis of fluorine-18 fluoromisonidazole

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12 December 2020

6-[18F]fluorometaraminol: a radiotracer for in vivo mapping of adrenergic nerves of the heart

1 reference

12 December 2020

Ligands and tracers for PET studies of the 5-HT system--current status

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12 December 2020

Syntheses and specific activity determinations of no-carrier-added (NCA) F-18-labeled butyrophenone neuroleptics--benperidol, haloperidol, spiroperidol, and pipamperone.

1 reference

12 December 2020

New labelled ligand for in-vivo studies of opioid physiology

1 reference

12 December 2020

Comparative in vivo metabolism of 6-[18F]fluoro-L-dopa and [3H]L-dopa in rats

1 reference

12 December 2020

(-)-S-[3H]CGP-12177 and its use to determine the rate constants of unlabeled beta-adrenergic antagonists

1 reference

12 December 2020

Myocardial kinetics of fluorine-18 misonidazole: a marker of hypoxic myocardium

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12 December 2020

Synthesis of no-carrier-added N-([18F]fluoroalkyl)spiperone derivatives

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12 December 2020

Synthesis of [11C]SCH 23390 for dopamine D1 receptor studies

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12 December 2020

A method of studying pharmacokinetics in man at picomolar drug concentrations

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12 December 2020

External imaging of cerebral muscarinic acetylcholine receptors

1 reference

12 December 2020

Imaging muscarinic cholinergic receptors in human brain in vivo with Spect, [123I]4-iododexetimide, and [123I]4-iodolevetimide

1 reference

12 December 2020

Stereoselective binding of 11C-raclopride in living human brain--a search for extrastriatal central D2-dopamine receptors by PET.

1 reference

12 December 2020

The distribution of the muscarinic acetylcholine receptor antagonists, quinuclidinyl benzilate and quinuclidinyl benzilate methiodide (both tritiated), in rat, guinea pig, and rabbit

1 reference

12 December 2020

Positron tomography. A new method for in vivo brain studies of benzodiazepine, in animal and in man

1 reference

12 December 2020

Radioiodinated beta-methyl phenyl fatty acids as potential tracers for myocardial imaging and metabolism

1 reference

12 December 2020

Evaluation of 75Br-labelled butyrophenone neuroleptics for imaging cerebral dopaminergic receptor areas using positron emission tomography

1 reference

12 December 2020

Metabolic fate of radiolabeled palmitate in ischemic canine myocardium: implications for positron emission tomography.

1 reference

12 December 2020

Synthesis, rodent biodistribution, dosimetry, metabolism, and monkey images of carbon-11-labeled (+)-2 alpha-tropanyl benzilate: a central muscarinic receptor imaging agent

1 reference

12 December 2020

In vivo cerebral protein synthesis rates with leucyl-transfer RNA used as a precursor pool: determination of biochemical parameters to structure tracer kinetic models for positron emission tomography

1 reference

12 December 2020

[125I] 3-quinuclidinyl 4-iodobenzilate: a high affinity, high specific activity radioligand for the M1 and M2-acetylcholine receptors

1 reference

12 December 2020

In vivo SPECT imaging of CNS D-2 dopamine receptors: initial studies with iodine-123-IBZM in humans.

1 reference

12 December 2020

In vitro and in vivo evaluation of iodine-123-Ro 16-0154: a new imaging agent for SPECT investigations of benzodiazepine receptors

1 reference

12 December 2020

Synthesis of an (iodovinyl)misonidazole derivative for hypoxia imaging.

1 reference

12 December 2020

Radiolabeled meta-iodobenzylguanidine: pharmacology and clinical studies

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12 December 2020

Positron tomography of a radio-brominated analog of the D1/DA1 antagonist, SCH 23390.

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12 December 2020

Pharmacological implications for neuroreceptor imaging

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12 December 2020

Visualisation of 11C-flunitrazepam displacement in the brain of the live baboon

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12 December 2020

A radiotracer for mapping cholinergic neurons of the brain

1 reference

12 December 2020

Comparative evaluation of fatty acids labeled with C-11, Cl-34m, Br-77, and I-123 for metabolic studies of the myocardium: concise communication

1 reference

12 December 2020

[Myocardial scintigraphy with iodine 123-labeled fatty acids]

1 reference

12 December 2020

[76Br]bromolisuride: a new tool for quantitative in vivo imaging of D-2 dopamine receptors

1 reference

12 December 2020

A Comparative PET-study of five carbon-11 or fluorine-18 labelled salicylamides. Preparation and in vitro dopamine D-2 receptor binding

1 reference

12 December 2020

Radioiodinated 15-(p-iodophenyl)-3,3-dimethylpentadecanoic acid: a useful new agent to evaluate myocardial fatty acid uptake

1 reference

12 December 2020

PET measurement of D2 and S2 receptor binding of 3-N-[( 2'-18F]fluoroethyl)spiperone in baboon brain

1 reference

12 December 2020

Estimation of local cerebral glucose utilization by positron emission tomography: comparison of [18F]2-fluoro-2-deoxy-D-glucose and [18F]2-fluoro-2-deoxy-D-mannose in patients with focal brain lesions

1 reference

12 December 2020

In vivo labeling of the dopamine D2 receptor with N-11C-methyl-benperidol

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12 December 2020

14(R,S)-[18F]fluoro-6-thia-heptadecanoic acid (FTHA): evaluation in mouse of a new probe of myocardial utilization of long chain fatty acids

1 reference

12 December 2020

[18F]setoperone: a new high-affinity ligand for positron emission tomography study of the serotonin-2 receptors in baboon brain in vivo

1 reference

12 December 2020

Nigrostriatal function in humans studied with positron emission tomography

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12 December 2020

Synthesis, affinity and specificity of 18F-setoperone, a potential ligand for in-vivo imaging of cortical serotonin receptors

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12 December 2020

Effects of atropine treatment on in vitro and in vivo binding of 4-[125I]-dexetimide to central and myocardial muscarinic receptors

1 reference

12 December 2020

Comparison of high specific activity (-) and (+)-6-[18F]fluoronorepinephrine and 6-[18F]fluorodopamine in baboons: heart uptake, metabolism and the effect of desipramine

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12 December 2020

Identifiers

DOI

10.1007/BF00185860

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13 August 2017

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